Results 21 to 30 of about 15,009 (224)

Antidiabetes, antidyslipidemia, hemoprotective, nehproprotective and hepatoprotective effect of ethanol extract of Jatropha tanjorensis leaf against alloxan induced diabetes in rats

open access: yesJournal of Herbal Drugs, 2022
Background & Aim: Management/ treatment of illness and maintenance of well-being using herbal medicines is the oldest and most popular form of healthcare practice known to humankind that has been practiced by all cultures in all ages throughout the ...
Chika Cecilia Unegbu   +5 more
doaj   +1 more source

Nephroprotective Effect of <i>Sansevieria trifasciata</i>. [PDF]

open access: yesInt J Mol Sci
Kidney diseases represent an increasingly significant global public health challenge, with an estimated prevalence of around 10% among adults and a rising trend influenced by factors such as population aging and exposure to nephrotoxic agents. Given the limitations of conventional treatments, which often only slow disease progression and may cause ...
Ramos Islas J   +11 more
europepmc   +3 more sources

SGLT2 Inhibitors and the Diabetic Kidney [PDF]

open access: yes, 2016
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression ...
Busetto, Luca   +4 more
core   +1 more source

Protective Effects of Traditional Polyherbs on Cisplatin-Induced Acute Kidney Injury Cell Model by Inhibiting Oxidative Stress and MAPK Signaling Pathway

open access: yesMolecules, 2020
Acute kidney injury (AKI) is a disease caused by sudden renal dysfunction, which is an important risk factor for chronic renal failure. However, there is no effective treatment for renal impairment.
VinayKumar Dachuri   +4 more
doaj   +1 more source

Involvement of heparanase in the pathogenesis of acute kidney injury: Nephroprotective effect of PG545 [PDF]

open access: yes, 2017
Despite the high prevalence of acute kidney injury (AKI) and its association with increased morbidity and mortality, therapeutic approaches for AKI are disappointing. This is largely attributed to poor understanding of the pathogenesis of AKI. Heparanase,
Abassi, Zaid   +16 more
core   +1 more source

Ameliorative effect of cotreatment with the methanolic leaf extract of Urtica dioica on acute kidney injury induced by gentamicin in rats [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2020
Objective: Effects of cotreatment with Urtica dioica (UD) methanolic leaf extract on gentamicin (GM)-induced acute kidney injury were evaluated in rats. Materials and Methods: Male Wistar rats (n=32) were separated into four groups. Gentamicin (100 mg/kg/
Saeed Hajihashemi   +3 more
doaj   +1 more source

Leonotis ocymifolia (Burm.f.) Iwarsson aerial parts aqueous extract mitigates cisplatin-induced nephrotoxicity via attenuation of inflammation, and DNA damage

open access: yesFrontiers in Pharmacology, 2023
Herein, we explored the protective effect of Leonotis ocymifolia (Burm.f.) Iwarsson aerial parts extract (LO) against cisplatin (CP)-induced nephrotoxicity in rats and profiled their phytocontents.
Afoua Mufti   +7 more
doaj   +1 more source

Sphingosine 1-phosphate in renal diseases [PDF]

open access: yes, 2013
Because of its highly bioactive properties sphingosine 1-phosphate (S1P) is an attractive target for the treatment of several diseases. Since the expression of sphingosine kinases as well as S1P receptors was demonstrated in the kidney, questions about ...
Huwiler, Andrea   +2 more
core   +2 more sources

The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]

open access: yes, 2013
The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves   +3 more
core   +1 more source

Silymarin inhibits cisplatin-mediated apoptosis via inhibition of hydrogen peroxide and hydroxyl radical generation [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2015
Cisplatin mediated nephrotoxicity has been continuously reported and recognized as a major obstacle for cisplatinbased chemotherapy. The present study aimed to demonstrate the potential use of silymarin, an extract from the seed of Silybum marianum L.,
Angkana Tantituvanont   +7 more
doaj  

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