Results 11 to 20 of about 121,280 (344)

Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy [PDF]

The Korean Journal of Internal Medicine, 2021
Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity.
Jin Won Kim, Sun Ah Nam, Eunjeong Seo, Jong Young Lee, Dohui Kim, Ji Hyeon Ju, Sun Woo Lim, Hong Lim Kim, Hyung Wook Kim, Chul Woo Yang, Jin Kim, Dong Sung Kim, Yong Kyun Kim   +12 more
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Sex Difference in Cisplatin-Induced Nephrotoxicity: Laboratory and Clinical Findings

Journal of Toxicology, 2022
Cisplatin (CP) as the most important anticancer drug has limited usage due to a lot of side effects such as nephrotoxicity. Additionally, nephrotoxicity is gender/sex-related.
Fatemeh Eshraghi-Jazi, Mehdi Nematbakhsh
doaj   +1 more source

A Potentially Less Nephrotoxicity of Carboplatin Over Cisplatin as Radiosensitizer in Head-neck Cancer

Asian Pacific Journal of Cancer Biology, 2022
Introduction: Head and neck cancers are the common cancers in developing countries, especially in Southeast Asia. Concurrent chemoradiation is the treatment of choice for locally advanced stage III to IVB squamous cell carcinoma of head and neck ...
Mahfujul Ahmed Riad
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Lithium nephrotoxicity [PDF]

International Journal of Bipolar Disorders, 2015
AbstractReports of toxic effects on the kidney of lithium treatment emerged very soon after lithium therapy was introduced. Lithium-induced nephrogenic diabetes insipidus is usually self-limiting or not clinically dangerous. Some reports of irreversible chronic kidney disease and renal failure were difficult to attribute to lithium treatment since ...
Azab, Abed N., Shnaider, Alla, Osher, Yamima, Wang, Dana, Bersudsky, Yuly, Belmaker, R. H.   +5 more
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Unveiling the mechanisms of nephrotoxicity caused by nephrotoxic compounds using toxicological network analysis

Molecular Therapy: Nucleic Acids, 2023
Billions of people worldwide have experienced irreversible kidney injuries, which is mainly attributed to the complexity of drug-induced nephrotoxicity.
Kexing Xi, Mengqing Zhang, Mingrui Li, Qiang Tang, Qi Zhao, Wei Chen   +5 more
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Comparison of Myelotoxicity and Nephrotoxicity Between Daily Low-Dose Cisplatin With Concurrent Radiation and Cyclic High-Dose Cisplatin in Non-Small Cell Lung Cancer Patients

Frontiers in Pharmacology, 2020
AimAntineoplastic effect of cisplatin, the first line treatment in non-small cell lung cancer (NSCLC), is hindered by its nephrotoxicity and myelotoxicity. Both low-dose and high-dose regimens are used in the management of NSCLC. The aim of this study is
Zulfan Zazuli, Zulfan Zazuli, Renate Kos, Joris D. Veltman, Wilma Uyterlinde, Cristina Longo, Paul Baas, Rosalinde Masereeuw, Susanne J. H. Vijverberg, Anke-Hilse Maitland-van der Zee   +9 more
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Atazanavir nephrotoxicity [PDF]

Clinical Kidney Journal, 2015
Atazanavir is commonly used as one of the key drugs in combination antiretroviral therapy for human immunodeficiency virus (HIV). However, atazanavir has the potential to yield its crystalline precipitation in urine and renal interstitial tissues, leading to crystalluria, urolithiasis, acute kidney injury (AKI) or chronic kidney disease (CKD).
Hara, Masaki, Suganuma, Akihiko, Yanagisawa, Naoki, Imamura, Akifumi, Hishima, Tsunekazu, Ando, Minoru   +5 more
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Inhibition of gentamicin–induced renal tubular cell necrosis [PDF]

Journal of Nephropathology, 2012
Gentamicin nephrotoxicity limit its usage against gram negative bacteria. Most researches showed that antioxidant agents improved gentamicin nephrotoxicity.
Majid Tavafi
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Bibliometric and visual analysis of nephrotoxicity research worldwide

Frontiers in Pharmacology, 2022
Background: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs.
Tianmu He, Tianmu He, Jingwen Ao, Cancan Duan, Rong Yan, Xiaomei Li, Liu Liu, Jianyong Zhang, Xiaofei Li, Xiaofei Li   +9 more
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Prospective observational study of the impact of plasma colistin levels in patients with carbapenem-resistant Acinetobacter baumannii pneumonia

Journal of Global Antimicrobial Resistance, 2021
: Objectives: Colistin, an important drug to treat carbapenem-resistant Acinetobacter baumannii (CRAB) infections, has a narrow therapeutic window with nephrotoxicity.
Yun-Jeong Jeong, Namyi Gu, Won Gun Kwack, Yunseong Kang, Seong Yeon Park, Young-Soon Yoon   +5 more
doaj   +1 more source