Results 11 to 20 of about 121,280 (344)

Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2021
Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity.
Jin Won Kim   +12 more
doaj   +1 more source

Sex Difference in Cisplatin-Induced Nephrotoxicity: Laboratory and Clinical Findings

open access: yesJournal of Toxicology, 2022
Cisplatin (CP) as the most important anticancer drug has limited usage due to a lot of side effects such as nephrotoxicity. Additionally, nephrotoxicity is gender/sex-related.
Fatemeh Eshraghi-Jazi, Mehdi Nematbakhsh
doaj   +1 more source

A Potentially Less Nephrotoxicity of Carboplatin Over Cisplatin as Radiosensitizer in Head-neck Cancer

open access: yesAsian Pacific Journal of Cancer Biology, 2022
Introduction: Head and neck cancers are the common cancers in developing countries, especially in Southeast Asia. Concurrent chemoradiation is the treatment of choice for locally advanced stage III to IVB squamous cell carcinoma of head and neck ...
Mahfujul Ahmed Riad
doaj   +1 more source

Lithium nephrotoxicity [PDF]

open access: yesInternational Journal of Bipolar Disorders, 2015
AbstractReports of toxic effects on the kidney of lithium treatment emerged very soon after lithium therapy was introduced. Lithium-induced nephrogenic diabetes insipidus is usually self-limiting or not clinically dangerous. Some reports of irreversible chronic kidney disease and renal failure were difficult to attribute to lithium treatment since ...
Azab, Abed N.   +5 more
openaire   +2 more sources

Unveiling the mechanisms of nephrotoxicity caused by nephrotoxic compounds using toxicological network analysis

open access: yesMolecular Therapy: Nucleic Acids, 2023
Billions of people worldwide have experienced irreversible kidney injuries, which is mainly attributed to the complexity of drug-induced nephrotoxicity.
Kexing Xi   +5 more
doaj   +1 more source

Comparison of Myelotoxicity and Nephrotoxicity Between Daily Low-Dose Cisplatin With Concurrent Radiation and Cyclic High-Dose Cisplatin in Non-Small Cell Lung Cancer Patients

open access: yesFrontiers in Pharmacology, 2020
AimAntineoplastic effect of cisplatin, the first line treatment in non-small cell lung cancer (NSCLC), is hindered by its nephrotoxicity and myelotoxicity. Both low-dose and high-dose regimens are used in the management of NSCLC. The aim of this study is
Zulfan Zazuli   +9 more
doaj   +1 more source

Atazanavir nephrotoxicity [PDF]

open access: yesClinical Kidney Journal, 2015
Atazanavir is commonly used as one of the key drugs in combination antiretroviral therapy for human immunodeficiency virus (HIV). However, atazanavir has the potential to yield its crystalline precipitation in urine and renal interstitial tissues, leading to crystalluria, urolithiasis, acute kidney injury (AKI) or chronic kidney disease (CKD).
Hara, Masaki   +5 more
openaire   +2 more sources

Inhibition of gentamicin–induced renal tubular cell necrosis [PDF]

open access: yesJournal of Nephropathology, 2012
Gentamicin nephrotoxicity limit its usage against gram negative bacteria. Most researches showed that antioxidant agents improved gentamicin nephrotoxicity.
Majid Tavafi
doaj   +1 more source

Bibliometric and visual analysis of nephrotoxicity research worldwide

open access: yesFrontiers in Pharmacology, 2022
Background: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs.
Tianmu He   +9 more
doaj   +1 more source

Prospective observational study of the impact of plasma colistin levels in patients with carbapenem-resistant Acinetobacter baumannii pneumonia

open access: yesJournal of Global Antimicrobial Resistance, 2021
: Objectives: Colistin, an important drug to treat carbapenem-resistant Acinetobacter baumannii (CRAB) infections, has a narrow therapeutic window with nephrotoxicity.
Yun-Jeong Jeong   +5 more
doaj   +1 more source

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