Results 21 to 30 of about 163,265 (345)
Türk Yoğun Bakim Derneği Dergisi, 2014 Objective: The aim of our study, is to determine the nephrotoxicity rates and risk factors for the development of nephrotoxicity by retrospective evaluation of patients who were given colistin therapy oncology hospital intensive care unit.
Menşure Kaya +6 more
doaj +1 more source
Protective effect of metalloporphyrins against cisplatin-induced kidney injury in mice. [PDF]
PLoS ONE, 2014 Oxidative and nitrative stress is a well-known phenomenon in cisplatin-induced nephrotoxicity. The purpose of this work is to study the role of two metalloporphyrins (FeTMPyP and MnTBAP), water soluble complexes, in cisplatin-induced renal damage and ...
Hao Pan +5 more
doaj +1 more source
Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
, 2018 Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Mechanism and reversal of drug-induced nephrotoxicity on a chip
Science Translational Medicine, 2021 Sensor-embedded spheroids-on-a-chip reveal the mechanisms of cisplatin- and cyclosporine-induced nephrotoxicity and identify a potential therapeutic.
Aaron Cohen +7 more
semanticscholar +1 more source
Nephrotoxicity in cancer treatment: An overview
World Journal of Clinical Oncology, 2020 Anticancer drug nephrotoxicity is an important and increasing adverse drug event that limits the efficacy of cancer treatment. The kidney is an important elimination pathway for many antineoplastic drugs and their metabolites, which occurs by glomerular ...
Maria Luísa Cordeiro Santos +4 more
semanticscholar +1 more source
Colistin Nephrotoxicity: Meta-Analysis of Randomized Controlled Trials
Open Forum Infectious Diseases, 2021 Background Nephrotoxicity is a known adverse effect of polymyxin antibiotics, including colistin. Although previous meta-analyses have aimed to characterize colistin-associated nephrotoxicity risk relative to other antibiotics, included studies were ...
K. Eljaaly +6 more
semanticscholar +1 more source
European Journal of Inflammation, 2019 The study aims at evaluating the protective effects of Ajwa dates extract against diclofenac sodium (DFS)-induced nephrotoxicity. A total of 30 male albino mice were divided into three groups. Group 1 received water per oral gavage for 14 days and saline
Heba M Eltahir +5 more
doaj +1 more source
Determination of colistin-related nephrotoxicity and risk factors in intensive care unit
İstanbul Kuzey Klinikleri, 2018 INTRODUCTION[|]Colistin is a cationic polypeptide antibiotic with a cyclic structure that belongs to the polymyxin group. It was banned from clinical use because of its significant renal side effects, such as nephrotoxicity.
Ayse Inci +4 more
doaj +1 more source
Experimental Cell Line Models for Nephrotoxicity Screening
Регуляторные исследования и экспертиза лекарственных средств, 2021 The aim of the study was to review literature data on cell models for experimental assessment of drug nephrotoxicity in vitro. Because of nephrotoxicity, 2% of new investigational medicinal products are discarded at the stage of preclinical in vivo ...
I. A. Mazerkina +4 more
doaj +1 more source
Journal of Biomedical Sciences, 2019 Cisplatin (cis-diamminedichloroplatinum II, CDDP) is one of the most effective chemotherapeutic agents. However, its clinical use is limited due to the severe side effects, including nephrotoxicity and acute kidney injury (AKI) which develop due to renal
V. Volarevic +6 more
semanticscholar +1 more source