Results 41 to 50 of about 163,265 (345)
Selenium alleviates porcine nephrotoxicity of ochratoxin A by improving selenoenzyme expression in vitro. [PDF]
PLoS ONE, 2015 Ochratoxin A (OTA), a mycotoxin, is a potent nephrotoxin in humans and animals. Selenium (Se) is an essential micronutrient for humans and animals, and plays a key role in antioxidant defense.
Fang Gan +4 more
doaj +1 more source
Colistin-induced Nephrotoxicity: Experience from a University Hospital
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021 Introduction: Colistin has been widely used in the treatment of infections caused by multidrug-resistant bacteria. This study aimed to determine the frequency and risk factors of colistin-related nephrotoxicity.
Pınar BAKIR EKİNCİ +5 more
doaj +1 more source
Mechanisms of Cisplatin Nephrotoxicity
Toxins, 2010 Cisplatin is a widely used and highly effective cancer chemotherapeutic agent. One of the limiting side effects of cisplatin use is nephrotoxicity. Research over the past 10 years has uncovered many of the cellular mechanisms which underlie cisplatin ...
Ronald P. Miller +3 more
semanticscholar +1 more source
Efficient Drug Screening and Nephrotoxicity Assessment on Co-culture Microfluidic Kidney Chip
Scientific Reports, 2020 The function and susceptibility of various drugs are tested with renal proximal tubular epithelial cells; yet, replicating the morphology and kidneys function using the currently available in vitro models remains difficult.
L. Yin +6 more
semanticscholar +1 more source
Restrictive antibiotic stewardship associated with reduced hospital mortality in gram-negative infection [PDF]
, 2017 Introduction: Antimicrobial stewardship has an important role in the control of Clostridium difficile infection (CDI) and antibiotic resistance. An important component of UK stewardship interventions is the restriction of broad-spectrum beta-lactam ...
Helps, Alieen +5 more
core +1 more source
Role of probiotics in the management of cisplatin-induced nephrotoxicity
Medicine in MicroecologyNew research shows that gut microbes have a role in the management of cisplatin-induced nephrotoxicity, with underlying processes involving mucosal and/or systemic inflammation or metabolic abnormalities.
Serina Easmin +7 more
doaj +1 more source
Acute kidney injury in critically ill cancer patients : an update [PDF]
, 2016 Patients with cancer represent a growing group among actual ICU admissions (up to 20 %). Due to their increased susceptibility to infectious and noninfectious complications related to the underlying cancer itself or its treatment, these patients ...
Benoit, Dominique +3 more
core +2 more sources
Journal of Pharmaceutical Health Care and Sciences, 2022 Background Cisplatin (CDDP)-induced nephrotoxicity is the most important complication of CDDP treatment. 5-Hydroxytryptamine type 3 receptor antagonists (5-HT3RAs) are widely used to prevent chemotherapy-induced nausea and vomiting (CINV).
Miho Takemura +5 more
doaj +1 more source
Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System
Advanced Functional Materials, EarlyView.A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim +4 more
wiley +1 more source
Frontiers in Pharmacology, 2021 Background: Nosocomial pneumonia is a major health and economic burden globally. Multidrug-resistant (MDR) or extensively drug-resistant (XDR) Gram-negative bacteria are the most common causative pathogens in critically-ill patients.
Huihui Zeng +16 more
doaj +1 more source