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The role of neprilysin in musculoskeletal diseases
Tissue and CellNeprilysin (NEP) is a membrane-bound endopeptidase that degrades various substrates, including natriuretic peptide, bradykinin, and substance P. It is distributed in various organs such as the heart, kidneys, and brain, regulating multiple physiological processes.
Zuping Wu +4 more
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The Neprilysin Family in Health and Disease
2006The mammalian neprilysin (NEP) family comprises at least seven members: NEP itself, Kell blood group antigen (KELL), the endothelin-converting enzymes (ECE-1 and ECE-2), the enzyme PEX, associated with X-linked hypophosphataemia, "X-converting enzyme" (XCE) a CNS-expressed orphan peptidase and a soluble, secreted endopeptidase (SEP).
A J, Turner +3 more
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Soluble Neprilysin and Corin Concentrations in Relation to Clinical Outcome in Chronic Heart Failure
JACC: Heart Failure, 2021Priya Vart +2 more
exaly
Convoluted molecular maze of neprilysin
Diagnosis, 2022Eleftherios P. Diamandis +2 more
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Tumour suppression through modulation of neprilysin signaling: A comprehensive review
European Journal of Pharmacology, 2021Runali Sankhe, Anoop Kishore
exaly
Estrogen regulates neprilysin activity in rat brain
Neuroscience Letters, 2004, Rosemarie Booze, Christopher B Eckman
exaly

