Results 171 to 180 of about 1,609,891 (295)

r Mackay’s trading post

, 1871
Almost a century after Mackay’s trading post was built and abandoned, the agency for the Oto-Missouria tribes was in Gage County around Beatrice. Sketched by Agent A. L.
Agent A. L. Green
core  

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Enzyme-Inspired Hydrogen-Bonded Organic Frameworks for Synergistic Capture, Detection, and Degradation of Nerve Agent Simulants. [PDF]

Adv Sci (Weinh)
Liu J, Mo G, Gao X, Deng Y, Wang Y, Niu Q, Lei Y, Fei B, Yip J, Zhang Z, Wu J, Bi Y, Ma K, Li Z, Li P.   +14 more
europepmc   +1 more source

Current Progress for Retrospective Identification of Nerve Agent Biomarkers in Biological Samples after Exposure. [PDF]

Toxics, 2022
Wang J, Lu X, Gao R, Pei C, Wang H.
europepmc   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Efficient Decontamination of Organophosphate-Based Pesticides and Nerve Agent Simulants Mediated by N‑Containing Nucleophiles. [PDF]

ACS Omega
Darkwah EK, Aryal P, Todeti S, Kenik J, Insall S, Reddy VP, Sotiriou-Leventis C.   +6 more
europepmc   +1 more source

Targeted Metabolomics of Organophosphate Pesticides and Chemical Warfare Nerve Agent Simulants Using High- and Low-Dose Exposure in Human Liver Microsomes. [PDF]

Metabolites, 2023
Agarwal G, Tichenor H, Roo S, Lane TR, Ekins S, McElroy CA.   +5 more
europepmc   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Iperpolarizzazione degli assoni motori periferici indotta da mutazione della connessina 32

, 2005
G. M. Fabrizi, L. Bertolasi, N. Bresolin, B. Bossi, G. Ardolino, N. Rizzuto, S. Barbieri, D. Pareyson, A. Polo, T. Cavallaro, A. Priori   +10 more
core   +2 more sources

Steric hindrance-engineered porous fluorescent films for ultrafast and ultrasensitive detection of nerve agent simulants. [PDF]

Chem Sci
Liu Y, Qiao M, Liu J, Wang G, Wang S, Wen R, Zhai Y, Ding L, Zhu X, Fang Y.   +9 more
europepmc   +1 more source