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Chemical warfare agents: II. nerve agents
Annals of Emergency Medicine, 1992Nerve agents are highly potent and rapidly acting organophosphorus compounds that irreversibly bind and inactive acetylcholinesterase. Only rarely have they been used in warfare, but their great lethality and the threat that they pose have encouraged production and stockpiling in large quantities.
F R, Sidell, J, Borak
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Science, 2018
Urgent efforts are underway to find better countermeasures to the potent chemical weapons.
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Urgent efforts are underway to find better countermeasures to the potent chemical weapons.
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Toxicokinetics of Nerve Agents
2007This chapter presents the subjects as in the second edition, updated with the latest results on the toxicokinetics of VX, mainly obtained after improvement of the analytical methodology. Toxicokinetic studies, together with toxicodynamic studies of nerve agents, provide a quantitative basis for the design of new strategies against intoxication with ...
Marcel J. van der Schans +2 more
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Therapy for Nerve Agent Poisoning
Archives of Neurology, 2004Neurologists need to familiarize themselves with nerve agents, the most toxic of the chemical warfare agents. Their mode of action lies within the nervous system, and nonneurologists will look to neurologists for expert advice on therapy. These agents cause rapid-onset cholinergic crisis amenable to prompt treatment with specific antidotes.
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