Results 31 to 40 of about 656,722 (293)

Neuropathophysiological potential of Guillain-Barré syndrome anti-ganglioside-complex antibodies at mouse motor nerve terminals [PDF]

, 2011
Objectives:  Anti-ganglioside antibodies are present in approximately half of Guillain–Barré syndrome (GBS) patients. Recently, it has been shown that a considerable proportion of these patients has serum antibodies against antigenic epitopes formed by a
Susumu Kusunoki, Tio-Gillen, Anne P., Plomp, J.J., Kusunoki, Susumu, Tio-Gillen, A.P., Willison, H.J., Broos, Ludo A.M., Ueda, M., Mark L. Kuijf, Ludo A. M. Broos, Kuijf, Mark L., Jacobs, B.C., Greenshields, Kay N., Jacobs, Bart C., Zitman, F.M.P., Hugh J. Willison, Anne P. Tio-Gillen, Masami Ueda, Kuijf, M.L., Jaap J. Plomp, Kusunoki, S., Greenshields, K.N., Plomp, Jaap J., Femke M. P. Zitman, Broos, L.A.M., Kay N. Greenshields, Ken-ichi Kaida, Willison, Hugh J., Bart C. Jacobs, Kaida, Ken Ichi, Kaida, K.I., Ueda, Masami, Zitman, Femke M.P.   +32 more
core   +1 more source

Sciatic nerve injury following analgesic drug injection in rats: A histopathological examination

İstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]Sciatic nerve neuropathy can be observed following intramuscular gluteal injections. The histopathological examination of sciatic nerve damage following intramuscular injection in the gluteal region for acute pain treatment is not feasible
Habib Bostan, Murat Çabalar, Serdar Altınay, Yıldıray Kalkan, Levent Tumkaya, Ayhan Kanat, Sabri Balık, Adem Erkut, Dudu Altuner, Ziya Salihoğlu, Abdulkadir Koçer   +10 more
doaj   +1 more source

Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration [PDF]

, 2010
Background: Microglia/macrophages and lymphocytes (T-cells) accumulate around motor and primary sensory neurons that are regenerating axons but there is little or no microglial activation or T-cell accumulation around axotomised intrinsic CNS neurons ...
Bernadette ZY Wong, Shokouhi, B.N., Lieberman, A.R., Tohyama, K., Wong Bernadette ZY, Campbell, G., Koujiro Tohyama, Anderson Patrick N, Gregor Campbell, Tohyama Koujiro, Campbell Gregor, Samir Siddiqui, Siddiqui, S., Patrick N Anderson, A Robert Lieberman, Bahman N Shokouhi, Wong, B.Z.Y., Shokouhi Bahman N, Anderson, P.N., Lieberman A Robert, Siddiqui Samir   +20 more
core   +1 more source

The Septum Inguinalis: A Clue to Hernia Genesis?

Journal of Investigative Surgery, 2020
Purpose: Double ipsilateral inguinal (“pantaloon”) hernias and also the more advanced “combined” inguinal hernia involve disruption of the inguinal floor.
Giuseppe Amato,, Piergiorgio Calò,, Vito Rodolico,, Roberto Puleio,, Antonino Agrusa,, Leonardo Gulotta,, Luca Gordini,, Giorgio Romano,   +7 more
doaj   +1 more source

Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging

Nature Communications, 2016
Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic ...
Feng Tian, Wenlong Yang, Daniel A. Mordes, Jin-Yuan Wang, Johnny S. Salameh, Joanie Mok, Jeannie Chew, Aarti Sharma, Ester Leno-Duran, Satomi Suzuki-Uematsu, Naoki Suzuki, Steve S. Han, Fa-Ke Lu, Minbiao Ji, Rosanna Zhang, Yue Liu, Jack Strominger, Neil A. Shneider, Leonard Petrucelli, X. Sunney Xie, Kevin Eggan   +20 more
doaj   +1 more source

6-Hydroxy flavone rescue ethanol-induced apoptotic neurodegeneration via activation of p-Akt signaling pathway in the developing mice brain

Khyber Medical University Journal
Objective: To investigate the potential use of 6-Hydroxyflavone (6-HF) activation of phosphorylated Akt (p-Akt) to reduce neurodegeneration induced by Ethanol in the developing mice brain of post-natal day 7 (PND-7) mice.
Mahia Tayyab, Rifat Jahan, Nousheen Bibi, Hafsa Nawaz, Amin Jan, Shahid Ali Shah   +5 more
doaj   +1 more source

CD82 protects against glaucomatous axonal transport deficits via mTORC1 activation in mice

Cell Death and Disease, 2021
Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by progressive optic nerve degeneration and retinal ganglion cell loss.
Meng Ye, Jingqiu Huang, Qianxue Mou, Jing Luo, Yuanyuan Hu, Xiaotong Lou, Ke Yao, Bowen Zhao, Qiming Duan, Xing Li, Hong Zhang, Yin Zhao   +11 more
doaj   +1 more source

Enhanced sciatic nerve regeneration by relieving iron-overloading and organelle stress with the nanofibrous P(MMD-co-LA)/DFO conduits

Materials Today Bio, 2022
Wallerian degeneration after peripheral nerve injury (PNI), that is, the autonomous degeneration of distal axons, leads to an imbalance of iron homeostasis and easily induces oxidative stress caused by iron overload.
Lei Han, Xianzhen Dong, Tong Qiu, Zhaona Dou, Lin Wu, Honglian Dai   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source