Results 101 to 110 of about 39,090 (270)

Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte‐mediated etiology of epileptic cortical thinning

Epilepsia Open, EarlyView.
Abstract Objective Focal epilepsy is characterized by progressive cortical thinning, particularly within limbic structures; however, whether this atrophy reflects acquired seizure‐induced damage or shared genetic predisposition remains unresolved. Methods We integrated genome‐wide association study (GWAS) summary statistics from the ILAE Consortium ...
Dingyuan Zhang, Qianqian Zhang, Guangming Li, Lingting Yu, Yanling Ma, Xiaoli Hong, Yujie Kui, Shanshan Cai, Jianguang Sun, Zechao Zhu   +9 more
wiley   +1 more source

Ataxia with oculomotor apraxia type 2: a clinical, pathologic, and genetic study [PDF]

, 2006
BACKGROUND: Ataxia with oculomotor apraxia type 2 (AOA2) is characterized by onset between age 10 and 22 years, cerebellar atrophy, peripheral neuropathy, oculomotor apraxia (OMA), and elevated serum alpha-fetoprotein (AFP) levels. Recessive mutations in
BANFI S, BARBIERI, FABRIZIO, CASALI C., CHESSA L, CRISCUOLO C, DE MICHELE, GIUSEPPE, DI GIANDOMENICO S, FILLA, ALESSANDRO, GALLOSTI L, GRIECO GS, MANCINI P, PIANE M, PIERELLI F, RIZZUTO N, SACCA', FRANCESCO, SANTORELLI FM   +15 more
core  

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

On axoplasmic pressure waves and their possible role in nerve impulse propagation

, 2010
It is suggested that the propagation of the action potential is accompanied by an axoplasmic pressure pulse propagating in the axoplasm along the axon length.
Rvachev, Marat M.
core   +1 more source

Gut microbiota regulates optic nerve fiber myelination

Frontiers in Cell and Developmental Biology
IntroductionRecent evidence supports the hypothesis of an association between gut microbiota and the pathogenesis of retinal and eye diseases, suggesting the existence of a gut-eye axis. However, no data are available on the possible effect of the gut microbiota on the optic nerve fiber maturation and myelin development.MethodsWe investigated the ...
Giulia Ronchi, Davide Pellegrino, Marwa El Soury, Olga Amato, Francesco Gaia, Sajjad Farzin, Raffaele Nuzzi, Marijana Basic, Silvia Bolsega, Stefano Geuna, Matilde Cescon, Kirsten Haastert-Talini, Kirsten Haastert-Talini, Giovanna Gambarotta   +13 more
openaire   +4 more sources

Exploration of a Multimodal Machine Learning Model Integrating Ultrasound and Clinical Indicators for the Diagnosis of Diabetic Peripheral Neuropathy

Journal of Ultrasound in Medicine, EarlyView.
Objectives Based on ultrasound technology and clinical indicators, this study intends to develop multiple risk prediction models for diabetic peripheral neuropathy (DPN), conduct comparative analyses of these models, and further evaluate and validate the diagnostic efficacy of the optimal model for DPN as well as its potential in clinical application ...
Bo‐yu She, Meng‐lu Song, Wen‐bin Chen, Kun‐bin Wu, Zhen‐han Lai   +4 more
wiley   +1 more source

Structural reorganization of the sciatic, peroneal, and tibial nerves during osteosynthesis of lower leg fracture and after fracture consolidation (an experimental study)

Анналы клинической и экспериментальной неврологии, 2017
The study purpose was to identify histological changes in the peripheral nerves and determine functional significance of subclinical neuropathy in experimental simulation of lower leg fractures.
T. N. Varsegova, N. A. Shchudlo, M. M. Shchudlo, M. A. Stepanov, M. S. Sayfutdinov   +4 more
doaj   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

A quantitative evaluation of gross versus histologic neuroma formation in a rabbit forelimb amputation model: potential implications for the operative treatment and study of neuromas

Journal of Brachial Plexus and Peripheral Nerve Injury, 2011
Background Surgical treatment of neuromas involves excision of neuromas proximally to the level of grossly "normal" fascicles; however, proximal changes at the axonal level may have both functional and therapeutic implications with regard to amputated ...
Kuiken Todd A, Ding Xianzhong, O'Shaughnessy Kristina D, Kim Peter S, Ko Jason H, Dumanian Gregory A   +5 more
doaj   +1 more source

Outcomes and Innervation of Gracilis for Pediatric Facial Paralysis: A Systematic Review

The Laryngoscope, EarlyView.
This systematic review compares innervation techniques for gracilis free muscle transfer in pediatric facial paralysis. Masseteric innervation produced the greatest commissure excursion, cross‐facial nerve grafting enabled spontaneous smiles, and dual innervation balanced both with high satisfaction and low complication rates across techniques ...
Kaiwen Chen, Shaun A. Nguyen, Warren B. Chun, Charles M. Henry, Matthew H. Cheung, Cory Hyun‐su Kim, Michelle S. Hwang   +6 more
wiley   +1 more source