Results 51 to 60 of about 39,698 (257)

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Retrolental fibroplasias: What lies beneath?

GMS Ophthalmology Cases, 2020
A nine-month-old female baby with normal birth history presented with her mother complaining of a white spot in the baby’s right eye, which the mother had noticed at five months of age.
Sen, Parveen, Shah, Dhaivat
doaj   +1 more source

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

Advanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti, Edwige Rice, Franck Desmoulin, Maylis Combeau, Mélissa Parny, Lorenne Robert, Etienne Buscail, Barbara Bournet, Nathalie Vergnolle, Isabelle Raymond‐Letron, Isabelle Loubinoux, Carla Cirillo   +11 more
wiley   +1 more source

Polarimetric nerve fiber analysis in patients with peripapillary myelinated retinal nerve fibers [PDF]

Acta Ophthalmologica Scandinavica, 2001
ABSTRACT. Purpose: The aim of this study was to compare the RNFL thickness in eyes with myelinated retinal nerve fibers (MRNF) and age, sex‐matched controls using scanning laser polarimetry.Methods: Seventeen patients with MRNF underwent a comprehensive ophthalmological examination including automated visual field testing, and scanning laser ...
S, Tatlipinar, S, Gedik, M C, Mocan, M, Orhan, M, Irkeç   +4 more
openaire   +2 more sources

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Modulation of Calcitonin, Parathyroid Hormone, and Thyroid Hormone Secretion by Electrical Stimulation of Sympathetic and Parasympathetic Nerves in Anesthetized Rats

Frontiers in Neuroscience, 2017
The thyroid and parathyroid glands are dually innervated by sympathetic (cervical sympathetic trunk [CST]) and parasympathetic (superior laryngeal nerve [SLN]) nerve fibers.
Harumi Hotta, Akiko Onda, Harue Suzuki, Philip Milliken, Arun Sridhar   +4 more
doaj   +1 more source

Multi-electrode nerve cuff recording - model analysis of the effects of finite cuff length [PDF]

, 2005
The effect of finite cuff length on the signals recorded by electrodes at different positions along the nerve was analysed in a model study. Relations were derived using a one-dimensional model.
Buschman, H.P.J., Marani, Enrico, Tonis, T., Tönis, Thijs, Veltink, Petrus H., Wesselink, W.A.   +5 more
core   +1 more source

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source

Electrode geometry and preferential stimulation of spinal nerve fibers having different orientations: a modeling study [PDF]

, 1992
In a computer modeling study of epidural spinal cord stimulation using a longitudinal array of electrode contacts, the effect of contact geometry and contact combination on the threshold voltages for stimulation of dorsal column (DC) fibers and dorsal ...
Holsheimer, Jan, Struijk, Johannes J.
core   +2 more sources

Anodal Block Of Myelinated Nerve Fibers: A Modeling Study [PDF]

[1990] Proceedings of the Twelfth Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2005
Electrical stimulation of myelinated nerve fibers was analyzed, using point sources in a simple (homogeneous) volume conductor model and a dynamic model of mammalian nerve fiber properties. The stimulus conditions resulting in anodal block of a propagating action potential were calculated as a function of electrode position.
Holsheimer, Jan, van der Heide, G.G., Struijk, J.J.   +2 more
openaire   +2 more sources