Results 91 to 100 of about 2,134,725 (245)

Nerve growth factor: from the early discoveries to the potential clinical use

Journal of Translational Medicine, 2012
The physiological role of the neurotrophin nerve growth factor (NGF) has been characterized, since its discovery in the 1950s, first in the sensory and autonomic nervous system, then in central nervous, endocrine and immune systems. NGF plays its trophic
L. Aloe, M. Rocco, P. Bianchi, L. Manni
semanticscholar   +1 more source

The evolution of nerve growth factor inhibition in clinical medicine

Nature Reviews Rheumatology, 2020
B. Wise, M. Seidel, N. Lane
semanticscholar   +1 more source

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

Journal of Cell Biology, 1988
We have developed an experimental paradigm to study the mechanism by which nerve growth factor (NGF) allows the survival of sympathetic neurons. Dissociated sympathetic neurons from embryonic day-21 rats were grown in vitro for 7 d in the presence of NGF.
David P. Martin, R. Schmidt, P. Distefano, O. H. Lowry, J. Carter, E. Johnson   +5 more
semanticscholar   +1 more source

Aberrant Expression of Histamine-independent Pruritogenic Mediators in Keratinocytes may be Involved in the Pathogenesis of Prurigo Nodularis

Acta Dermato-Venereologica, 2019
Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in ...
Weilong Zhong, Xia Wu, Wei Zhang, Jie Zhang, Xiaofan Chen, Shihong Chen, Haiyan Huang, Yong Yang, Bo Yu, Xia Dou   +9 more
doaj   +1 more source

Nerve growth factor with fibrin glue in end-to-side nerve repair in rats [PDF]

Acta Cirúrgica Brasileira, 2012
PURPOSE: To determine the effects of end-to-side nerve repair performed only with fibrin glue containing nerve growth in rats. METHODS: Seventy two Wistar rats were divided into six equal groups: group A was not submitted to nerve section; group B was ...
Daniel Nunes e Silva, Andréia Conceição Milan Brochado Antoniolli da Silva, Ricardo Dutra Aydos, Fausto Viterbo, Elenir Rose Jardim Cury Pontes, Danilo Nakao Odashiro, Rafael José de Castro, Diogo Gomes Augusto   +7 more
doaj   +1 more source

Mental disorders, functional impairment, and nerve growth factor

Psychology Research and Behavior Management, 2016
Fanny Helena Martins Salles,1 Pedro San Martin Soares,1 Carolina David Wiener,1 Thaise Campos Mondin,1 Paula Moraes da Silva,1 Karen Jansen,1–3 Luciano Dias de Mattos Souza,1 Ricardo Azevedo da Silva,1 Jean Pierre Oses1–3 1Translational ...
Salles FHM, Soares PSM, Wiener CD, Mondin TC, da Silva PM, Jansen K, de Mattos Souza LD, da Silva RA, Oses JP   +8 more
doaj  

Characterisation of ERK distribution and activity in rat pheochromocytoma cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Biology at Massey University [PDF]

, 1998
Nerve growth factor (NGF) binds to the NGF receptor, TrkA, at the tips of nerve cell axons, sending a signal that prevents programmed cell death and causes survival, growth, and differentiation of the nerve cell.
MacCormick, Matthew Edgar
core  

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

Proceedings of the National Academy of Sciences of the United States of America, 1976
L. Greene, A. Tischler
semanticscholar   +1 more source

Advances in sciatic nerve regeneration: A review of contemporary techniques

Regenerative Therapy
Sciatic nerve injury, affecting the longest and thickest nerve in the human body, often leads to severe pain, weakness, and impaired motor function in the lower extremities.
Sardar Ali, Ming Sun, Muhammad Nadeem Khan, Fang Qiang   +3 more
doaj   +1 more source

Nerve growth factor (NGF) in the central nervous system [PDF]

, 1990
Aguayo, A., Bandtlow, Christine, Bjorklund, A., Hengerer, Bastian, Heumann, Rolf, Lindholm, Dan, Meyer, Michael, Ottoson, D., Spranger, Matthias, Thoenen, Hans   +9 more
core   +1 more source