Results 11 to 20 of about 1,698,099 (352)

Biological characteristics of dynamic expression of nerve regeneration related growth factors in dorsal root ganglia after peripheral nerve injury

open access: yesNeural Regeneration Research, 2020
The regenerative capacity of peripheral nerves is limited after nerve injury. A number of growth factors modulate many cellular behaviors, such as proliferation and migration, and may contribute to nerve repair and regeneration.
Yin-Ying Shen   +5 more
doaj   +1 more source

Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects

open access: yesNeural Regeneration Research, 2023
Studies have shown that human hair keratin (HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secrete nerve growth factor, which ...
Han-Jun Qin   +7 more
doaj   +1 more source

In vitro study of decellularized rat tissues for nerve regeneration

open access: yesFrontiers in Neurology, 2022
Peripheral nerve injuries cause an absence or destruction of nerves. Decellularized nerves, acting as a replacement for autografts, have been investigated in the promotion of nerve repair and regeneration, always being incorporated with stem cells or ...
Kai Ye   +16 more
doaj   +1 more source

A Review on Microfluidic Platforms Applied to Nerve Regeneration

open access: yesApplied Sciences, 2022
In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory ...
Chuankai Dai   +4 more
doaj   +1 more source

Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro

open access: yesNeural Regeneration Research, 2020
Neurotrophins play a major role in the regulation of neuronal growth such as neurite sprouting or regeneration in response to nerve injuries. The role of nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor in maintaining the ...
Michele Fornaro   +6 more
doaj   +1 more source

Polydopamine-modified chitin conduits with sustained release of bioactive peptides enhance peripheral nerve regeneration in rats

open access: yesNeural Regeneration Research, 2022
[INLINE:1] The introduction of neurotrophic factors into injured peripheral nerve sites is beneficial to peripheral nerve regeneration. However, neurotrophic factors are rapidly degraded in vivo and obstruct axonal regeneration when used at a ...
Ci Li   +7 more
doaj   +1 more source

Cavernous nerve reconstruction with autologous vein graft and platelet-derived growth factors

open access: yesAsian Journal of Andrology, 2017
In this study, we investigated the feasibility of using autologous vein graft and platelet-derived growth factors to bridge transected cavernous nerve in a rat model.
Xie-Gang Ding   +4 more
doaj   +1 more source

Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Treat Cutaneous Nerve Damage and Promote Wound Healing

open access: yesFrontiers in Cellular Neuroscience, 2022
Wound repair is a key step in the treatment of skin injury caused by burn, surgery, and trauma. Various stem cells have been proven to promote wound healing and skin regeneration as candidate seed cells.
Ziying Zhu   +8 more
doaj   +1 more source

Neuropathological and Behavioral Consequences of Adeno-Associated Viral Vector-Mediated Continuous Intrastriatal Neurotrophin Delivery in a Focal Ischemia Model in Rats

open access: yesNeurobiology of Disease, 2002
Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) were continuously delivered to the striatum at biologically active levels via recombinant adeno-associated viral (rAAV) gene transfer 4–5 weeks prior to 30 min of middle cerebral ...
Gunnar Andsberg   +5 more
doaj   +1 more source

The role of growth factors in nerve regeneration.

open access: yesDrug Discoveries & Therapeutics, 2016
Nerve injuries result in functional loss in the innervated organ or body parts, and recovery is difficult unless surgical treatment has been done. Different surgical treatments have been suggested for nerve repair.
M. Önger   +5 more
semanticscholar   +1 more source

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