Results 11 to 20 of about 223,909 (214)

In vitro study of decellularized rat tissues for nerve regeneration

open access: yesFrontiers in Neurology, 2022
Peripheral nerve injuries cause an absence or destruction of nerves. Decellularized nerves, acting as a replacement for autografts, have been investigated in the promotion of nerve repair and regeneration, always being incorporated with stem cells or ...
Kai Ye   +16 more
doaj   +1 more source

A Review on Microfluidic Platforms Applied to Nerve Regeneration

open access: yesApplied Sciences, 2022
In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory ...
Chuankai Dai   +4 more
doaj   +1 more source

Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro

open access: yesNeural Regeneration Research, 2020
Neurotrophins play a major role in the regulation of neuronal growth such as neurite sprouting or regeneration in response to nerve injuries. The role of nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor in maintaining the ...
Michele Fornaro   +6 more
doaj   +1 more source

Polydopamine-modified chitin conduits with sustained release of bioactive peptides enhance peripheral nerve regeneration in rats

open access: yesNeural Regeneration Research, 2022
[INLINE:1] The introduction of neurotrophic factors into injured peripheral nerve sites is beneficial to peripheral nerve regeneration. However, neurotrophic factors are rapidly degraded in vivo and obstruct axonal regeneration when used at a ...
Ci Li   +7 more
doaj   +1 more source

Cavernous nerve reconstruction with autologous vein graft and platelet-derived growth factors

open access: yesAsian Journal of Andrology, 2017
In this study, we investigated the feasibility of using autologous vein graft and platelet-derived growth factors to bridge transected cavernous nerve in a rat model.
Xie-Gang Ding   +4 more
doaj   +1 more source

Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Treat Cutaneous Nerve Damage and Promote Wound Healing

open access: yesFrontiers in Cellular Neuroscience, 2022
Wound repair is a key step in the treatment of skin injury caused by burn, surgery, and trauma. Various stem cells have been proven to promote wound healing and skin regeneration as candidate seed cells.
Ziying Zhu   +8 more
doaj   +1 more source

Increased Brain-Derived Neurotrophic Factor Levels in Cerebrospinal Fluid During the Acute Phase in TBI-Induced Mechanical Allodynia in the Rat Model

open access: yesJournal of Pain Research, 2022
Wangseok Do,1 Jiseok Baik,1,2 Soeun Jeon,1 Chang-Min You,1 Dahyun Kang,1 Young-Hoon Jung,1 Jiyoon Lee,3 Hae-Kyu Kim1,2 1Department of Anesthesia and Pain Medicine and Biomedical Research Institute Pusan National University Hospital, Busan, Republic of ...
Do W   +7 more
doaj  

Nerve growth factors.

open access: yesNihon Naika Gakkai Zasshi, 1992
神経成長因子(nerve growth factor; NGF)は,知覚神経二ューロン,交感神経ニューロン,中枢の一部のコリン系ニューロンの分化・成熟を促し,生存・機能を維持し,突起伸展を引き起こす,分子量約26000の蛋白質である. NGFは,神経科学,発生学の分野において最も古くから実体の明らかにされていた分子のひとつで, NGFの研究で得られた膨大な知見から神経回路の形成過程や調節機構の概要が窺い知ることができるようになった.最近では, NGFを投与すると,末梢神経の軸索再生が促進されること,遅発性ニューロン死が抑制されること,老化による学習記憶能力低下が抑制されること,などが報告され,臨床応用への期待も高まってきている.
Furukawa S, Furukawa Y
openaire   +4 more sources

Neuropathological and Behavioral Consequences of Adeno-Associated Viral Vector-Mediated Continuous Intrastriatal Neurotrophin Delivery in a Focal Ischemia Model in Rats

open access: yesNeurobiology of Disease, 2002
Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) were continuously delivered to the striatum at biologically active levels via recombinant adeno-associated viral (rAAV) gene transfer 4–5 weeks prior to 30 min of middle cerebral ...
Gunnar Andsberg   +5 more
doaj   +1 more source

White Matter Tract Integrity in Alzheimer's Disease vs. Late Onset Bipolar Disorder and Its Correlation with Systemic Inflammation and Oxidative Stress Biomarkers

open access: yesFrontiers in Aging Neuroscience, 2017
Background: Late Onset Bipolar Disorder (LOBD) is the development of Bipolar Disorder (BD) at an age above 50 years old. It is often difficult to differentiate from other aging dementias, such as Alzheimer's Disease (AD), because they share cognitive and
Ariadna Besga   +12 more
doaj   +1 more source

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