Results 11 to 20 of about 1,869,384 (384)

Neurotrophic factors and corneal nerve regeneration [PDF]

open access: yesNeural Regeneration Research, 2017
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
M. Sacchetti, A. Lambiase
semanticscholar   +4 more sources

Optogenetic control of nerve growth [PDF]

open access: yesScientific Reports, 2015
Due to the limited regenerative ability of neural tissue, a diverse set of biochemical and biophysical cues for increasing nerve growth has been investigated, including neurotrophic factors, topography and electrical stimulation.
Seongjun Park   +6 more
semanticscholar   +3 more sources

Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects

open access: yesNeural Regeneration Research, 2023
Studies have shown that human hair keratin (HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secrete nerve growth factor, which ...
Han-Jun Qin   +7 more
doaj   +1 more source

In vitro study of decellularized rat tissues for nerve regeneration

open access: yesFrontiers in Neurology, 2022
Peripheral nerve injuries cause an absence or destruction of nerves. Decellularized nerves, acting as a replacement for autografts, have been investigated in the promotion of nerve repair and regeneration, always being incorporated with stem cells or ...
Kai Ye   +16 more
doaj   +1 more source

A Review on Microfluidic Platforms Applied to Nerve Regeneration

open access: yesApplied Sciences, 2022
In recent decades, microfluidics have significantly advanced nerve regeneration research. Microfluidic devices can provide an accurate simulation of in vivo microenvironment for different research purposes such as analyzing myelin growth inhibitory ...
Chuankai Dai   +4 more
doaj   +1 more source

Aligned PCL Fiber Conduits Immobilized with Nerve Growth Factor Gradients Enhance and Direct Sciatic Nerve Regeneration

open access: yesAdvanced Functional Materials, 2020
Topographical guidance and chemotaxis are crucial factors for peripheral nerve regeneration. This study describes the preparation of highly aligned poly(ε‐caprolactone) (PCL) fiber conduits coated with a concentration gradient of nerve growth factor (NGF)
Lei Zhu   +11 more
semanticscholar   +1 more source

Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels. [PDF]

open access: yes, 2011
Previous work has revealed robust dorsal root ganglia neurite growth in hydrogels of chondroitin sulfate. In the current work, it was determined whether addition of a synthetic bioactive peptide could augment neurite growth in these matrices via enhanced
Beier, Brooke L   +3 more
core   +1 more source

Polydopamine-modified chitin conduits with sustained release of bioactive peptides enhance peripheral nerve regeneration in rats

open access: yesNeural Regeneration Research, 2022
[INLINE:1] The introduction of neurotrophic factors into injured peripheral nerve sites is beneficial to peripheral nerve regeneration. However, neurotrophic factors are rapidly degraded in vivo and obstruct axonal regeneration when used at a ...
Ci Li   +7 more
doaj   +1 more source

Ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons [PDF]

open access: yes, 1989
Although evidence obtained with the PC12 cell line has suggested a role for the ras oncogene proteins in the signal transduction of nerve growth factor-mediated fiber outgrowth, little is known about the signal transduction mechanisms involved in the ...
Barde, Y. A.   +5 more
core   +2 more sources

Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro

open access: yesNeural Regeneration Research, 2020
Neurotrophins play a major role in the regulation of neuronal growth such as neurite sprouting or regeneration in response to nerve injuries. The role of nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor in maintaining the ...
Michele Fornaro   +6 more
doaj   +1 more source

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