Results 41 to 50 of about 233,849 (156)

Unaltered low nerve growth factor and high brain-derived neurotrophic factor levels in plasma from patients with fibromyalgia after a 15-week progressive resistance exercise

Journal of Rehabilitation Medicine, 2019
Background: The pathophysiology of fibromyalgia includes central and peripheral factors. Neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor, are involved in peripheral and central nervous system development of pain and ...
Anna Jablochkova, Emmanuel Bäckryd, Eva Kosek, Kaisa Mannerkorpi, Malin Ernberg, Björn Gerdle, Bijar Ghafouri   +6 more
doaj   +1 more source

Exenatide promotes regeneration of injured rat sciatic nerve

Neural Regeneration Research, 2017
Damage to peripheral nerves results in partial or complete dysfunction. After peripheral nerve injuries, a full functional recovery usually cannot be achieved despite the standard surgical repairs. Neurotrophic factors and growth factors stimulate axonal
Ersin Kuyucu, Bilal Gümüs, Oytun Erbas, Fatih Oltulu, Arslan Bora   +4 more
doaj   +1 more source

ADSC-Exos outperform BMSC-Exos in alleviating hydrostatic pressure-induced injury to retinal ganglion cells by upregulating nerve growth factors. [PDF]

World J Stem Cells, 2023
Zheng ZK, Kong L, Dai M, Chen YD, Chen YH.   +4 more
europepmc   +1 more source

Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms

Neural Regeneration Research, 2015
Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent a promising young-state stem cell source for cell-based therapy. hUCMSC transplantation into the transected sciatic nerve promotes axonal regeneration and functional recovery.
Zhi-yuan Guo, Xun Sun, Xiao-long Xu, Jiang Peng, Yu Wang   +4 more
doaj   +1 more source

The Physiologic Basis of Molecular Therapeutics for Peripheral Nerve Injury: A Primer

Journal of Hand Surgery Global Online
Peripheral nerve injuries affect a significant number of patients who experience trauma affecting the hand and upper extremity. Improving unsatisfactory outcomes from repair of these injuries remains a clinical challenge despite advancements in ...
Marie C. Spezia, MSc, Christopher J. Dy, MD, MPH, David M. Brogan, MD, MSc   +2 more
doaj   +1 more source

Platelet-rich plasma in peripheral nerve injury repair: a comprehensive review of mechanisms, clinical applications, and therapeutic potential

Experimental Biology and Medicine
Peripheral nerve injuries (PNIs) pose a significant clinical challenge, often leading to incomplete functional recovery despite current treatments. Platelet-rich plasma (PRP), which contains high levels of growth factors and bioactive molecules, has ...
Kai Shang, Yang Liu, Abdul Qadeer
doaj   +1 more source

Assessing the itching intensity using visual analogue scales in atopic dermatitis patients against the background of a therapy with calcineurin inhibitors

Vestnik Dermatologii i Venerologii, 2017
Goal. To assess the effect of topical treatment of atopic dermatitis patients with the 0.1% tacrolimus ointment on the itching intensity and skin expression level of growth factor proteins affecting the intensity of cutaneous innervation.
V. V. Chikin, V. A. Smolyannikova, D. V. Proshutinskaya, M. A. Nefedova   +3 more
doaj   +1 more source

Correlation Between Brain-Derived Neurotrophic Factor and Cognitive Function in Older Adults

Medicinski Glasnik
Aim Brain Derived Neurotrophic Factor (BDNF) plays a crucial role in supporting neuronal survival, promoting neurogenesis, and enhancing synaptic plasticity, all of which are vital for cognitive health.
Effi Rohani Nuzul Sari, Fasihah Irfani Fitri, Aldy Safruddin Rambe, Taufik Ashar   +3 more
doaj   +1 more source

The role of kinases in peripheral nerve regeneration: mechanisms and implications

Frontiers in Neurology
Peripheral nerve injury disease is a prevalent traumatic condition in current medical practice. Despite the present treatment approaches, encompassing surgical sutures, autologous nerve or allograft nerve transplantation, tissue engineering techniques ...
Xu Zhang, Xu Zhang, Xuchu Duan, Xiaoyu Liu   +3 more
doaj   +1 more source

Conductive Nerve Conduits With Orientated Topological Structures From Ice‐Templating Technology

Smart Medicine
Artificial nerve conduits hold significant promise for treating nerve injuries, with researchers focusing on simplifying techniques to harness microstructures and functions to improve their therapeutic outcomes.
Hui Zhang, Kaichen Wang, Dongyu Xu, Shuangshuang Miao, Yanhong Dai, Panmiao Liu, Huan Wang   +6 more
doaj   +1 more source