Results 41 to 50 of about 1,827,011 (365)

From Single Neurons to Behavior in the Jellyfish Aurelia aurita [PDF]

eLife 2019;8:e50084, 2019
Jellyfish nerve nets provide insight into the origins of nervous systems, as both their taxonomic position and their evolutionary age imply that jellyfish resemble some of the earliest neuron-bearing, actively-swimming animals. Here we develop the first neuronal network model for the nerve nets of jellyfish.
arxiv   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Neurotrophins and neuropeptides as inflammatory mediators in case of chronic dermatosis

Vestnik Dermatologii i Venerologii, 2017
This literature review examines the role of neurotrophins and neuropeptides for the development of skin inflammatory reactions in case of chronic inflammatory dermatoses.
A. A. Kubanova, V. A. Smolyannikova, V. V. Chikin, A. E. Karamova   +3 more
doaj   +1 more source

Magnetic Nanoparticles for Neural Engineering [PDF]

Thanh, Nguyen TK (ed.). Clinical applications of magnetic nanoparticles: From Fabrication to Clinical Applications. CRC press, 2018
Magnetic nanoparticles (MNPs) are the foundation of several new strategies for neural repair and neurological therapies. The fact that a remote force can act on MNPs at the cytoplasmic space constitutes the essence of many new neurotherapeutic concepts. MNPs with a predesigned physicochemical characteristic can interact with external magnetic fields to
arxiv   +1 more source

The statistical mechanics of complex signaling networks : nerve growth factor signaling [PDF]

, 2004
It is becoming increasingly appreciated that the signal transduction systems used by eukaryotic cells to achieve a variety of essential responses represent highly complex networks rather than simple linear pathways. While significant effort is being made to experimentally measure the rate constants for individual steps in these signaling networks, many
arxiv   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Identification of adequate vehicles to carry nerve regeneration inducers using tubulisation

BMC Neuroscience, 2012
Background Axonal regeneration depends on many factors, such as the type of injury and repair, age, distance from the cell body and distance of the denervated muscle, loss of surrounding tissue and the type of injured nerve.
do Nascimento-Elias Adriana Helena, Fresnesdas Bruno César, Schiavoni Maria Cristina Lopes, de Almeida Natália Fernanda Gaspar, Santos Ana Paula, de Oliveira Ramos Jean, Junior Wilson Marques, Barreira Amilton Antunes   +7 more
doaj   +1 more source

Physical Stimulation Combined with Biomaterials Promotes Peripheral Nerve Injury Repair

Bioengineering, 2022
Peripheral nerve injury (PNI) is a clinical problem with high morbidity that can cause severe damage. Surgical suturing or implants are usually required due to the slow speed and numerous factors affecting repair after PNI.
Zhipeng Zeng, Yajing Yang, Junyong Deng, Muhammad Saif Ur Rahman, Chengmei Sun, Shanshan Xu   +5 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

The use of rh-NGF in the management of neurotrophic keratopathy

Frontiers in Ophthalmology
Neurotrophic keratitis or keratopathy (NK) is a degenerative corneal disease induced by impairment of the trigeminal nerve function. This condition may lead to persistent epithelial defects, corneal ulceration, and perforation.
Anna M. Roszkowska, Anna M. Roszkowska, Rosaria Spinella, Alessandro Calderone, Marianna Sindoni, Bogumił H. Wowra, Maciej Kozak, Katarzyna Sajak-Hydzik, Jorge Aliò   +8 more
doaj   +1 more source