Results 1 to 10 of about 1,942,100 (397)

The gut metabolite indole-3 propionate promotes nerve regeneration and repair

open access: yesNature, 2022
The regenerative potential of mammalian peripheral nervous system neurons after injury is critically limited by their slow axonal regenerative rate1. Regenerative ability is influenced by both injury-dependent and injury-independent mechanisms2.
, Guiping Kong, Luming Zhou
exaly   +2 more sources

Facial Nerve Repair following Acute Nerve Injury

open access: yesArchives of Plastic Surgery, 2022
Abstract Background Acute facial nerve iatrogenic or traumatic injury warrants rapid management with the goal of reestablishing nerve continuity within 72 hours. However, reconstructive efforts should be performed up to 12 months from the time of injury since facial musculature may still be viable and thus facial tone and function may be ...
Ehud Fliss   +7 more
openaire   +4 more sources

Protecting the Nerve Coaptation: Connector-Assisted Nerve Repair in Complex Injuries. [PDF]

open access: goldJ Hand Surg Glob Online
Zoghoul Alsmadi N   +5 more
europepmc   +3 more sources

Insights Into the Role and Potential of Schwann Cells for Peripheral Nerve Repair From Studies of Development and Injury

open access: yesFrontiers in Molecular Neuroscience, 2021
Peripheral nerve injuries arising from trauma or disease can lead to sensory and motor deficits and neuropathic pain. Despite the purported ability of the peripheral nerve to self-repair, lifelong disability is common. New molecular and cellular insights
Anjali Balakrishnan   +6 more
semanticscholar   +1 more source

Design and Fabrication of Polymeric Hydrogel Carrier for Nerve Repair

open access: yesPolymers, 2022
Nerve regeneration and repair still remain a huge challenge for both central nervous and peripheral nervous system. Although some therapeutic substances, including neuroprotective agents, clinical drugs and stem cells, as well as various growth factors ...
Xiaoyu Ma   +9 more
semanticscholar   +1 more source

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach

open access: yesJournal of Analytical Methods in Chemistry, 2022
Diosgenin, a steroidal sapogenin, has attracted attention worldwide owing to its pharmacological properties, including antitumor, cardiovascular protective, hypolipidemic, and anti-inflammatory effects.
Pei Liu   +10 more
doaj   +1 more source

Characterization of circular RNAs in dorsal root ganglia after central and peripheral axon injuries

open access: yesFrontiers in Cellular Neuroscience, 2022
In central nervous system, axons fail to regenerate after injury while in peripheral nervous system, axons retain certain regenerative ability. Dorsal root ganglion (DRG) neuron has an ascending central axon branch and a descending peripheral axon branch
Hong-Jun Cao   +4 more
doaj   +1 more source

The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration

open access: yesMolecular Medicine, 2023
Background Myelin sheath is a crucial accessory to the functional nerve-fiber unit, its disruption or loss can lead to axonal degeneration and subsequent neurodegenerative diseases (NDs).
Jinghui Xu   +13 more
doaj   +1 more source

Progress in methods for evaluating Schwann cell myelination and axonal growth in peripheral nerve regeneration via scaffolds

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Peripheral nerve injury (PNI) is a neurological disorder caused by trauma that is frequently induced by accidents, war, and surgical complications, which is of global significance.
Jue Ling   +8 more
doaj   +1 more source

Pure-silk fibroin hydrogel with stable aligned micropattern toward peripheral nerve regeneration

open access: yesNanotechnology Reviews, 2021
Successful repair of long-distance peripheral nerve injuries remains a challenge in the clinic. Rapid axon growth is a key to accelerate nerve regeneration.
Gu Xinyi   +6 more
doaj   +1 more source

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