Frontiers in Physiology, 2020 Although denervated muscle atrophy is common, the underlying molecular mechanism remains unelucidated. We have previously found that oxidative stress and inflammatory response may be early events that trigger denervated muscle atrophy. Isoquercitrin is a
Yuntian Shen +8 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2022 Objectives During French-door laminoplasty, a linear array transducer of IOUS was used to observe and record the spinal cord decompression. To acquire a higher-reliability method, and compare the in-observer and inter-observer reliability of two methods ...
Huachuan Wu +6 more
doaj +1 more source
Gpr126/Adgrg6 has Schwann cell autonomous and nonautonomous functions in peripheral nerve injury and repair [PDF]
, 2016 Schwann cells (SCs) are essential for proper peripheral nerve development and repair, although the mechanisms regulating these processes are incompletely understood.
Carlin, Dan +8 more
core +2 more sources
A United Kingdom survey of surgical technique and handling practice of inguinal canal structures during hernia surgery [PDF]
, 2006 Background: Recent trials have assessed the impact of elective nerve division on patient outcome after inguinal herniorrhaphy. The aim of this study was to establish UK surgical practice of handling of structures in the inguinal canal during ...
Bruce, Julie +4 more
core +1 more source
Frontiers in Physiology, 2018 Skeletal muscle atrophy occurs under various conditions, such as disuse, denervation, fasting, aging, and various diseases. Although the underlying molecular mechanisms are still not fully understood, skeletal muscle atrophy is closely associated with ...
Jiaying Qiu +10 more
doaj +1 more source
Axonal outgrowth is associated with increased ERK 1/2 activation but decreased caspase 3 linked cell death in Schwann cells after immediate nerve repair in rats [PDF]
, 2011 Background Extracellular-signal regulated kinase (ERK1/2) is activated by nerve damage and its activation precedes survival and proliferation of Schwann cells.
Yoshifumi Tsuda +2 more
core +2 more sources
Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation
Frontiers in Bioengineering and Biotechnology, 2022 Activation of mitophagy was considered to be a potential therapeutic strategy for intervertebral disc degeneration (IDD). There was evidence suggesting that hyaluronic acid (HA) can protect mitochondria from oxidative stress in chondrocytes, but its ...
Fu Zhang +11 more
doaj +1 more source
Visualizing peripheral nerve regeneration by whole mount staining. [PDF]
, 2015 Peripheral nerve trauma triggers a well characterised sequence of events both proximal and distal to the site of injury. Axons distal to the injury degenerate, Schwann cells convert to a repair supportive phenotype and macrophages enter the nerve to ...
A Erturk +31 more
core +3 more sources
The success of biomaterial-based tissue engineering strategies for peripheral nerve regeneration
Frontiers in Bioengineering and Biotechnology, 2022 Peripheral nerve injury is a clinically common injury that causes sensory dysfunction and locomotor system degeneration, which seriously affects the quality of the patients’ daily life.
Yuhui Jiang +7 more
doaj +1 more source
Estimations of topographically correct regeneration to nerve branches and skin after peripheral nerve injury and repair. [PDF]
, 2014 Peripheral nerve injury is typically associated with long-term disturbances in sensory localization, despite nerve repair and regeneration. Here, we investigate the extent of correct reinnervation by back-labeling neuronal soma with fluorescent tracers ...
Molander, Carl +2 more
core +2 more sources