Results 11 to 20 of about 1,041,327 (245)

An organized 3D in vitro model for peripheral nerve studies [PDF]

, 2013
Three-dimensional cell cultures have been proposed to address the limitations in two-dimensional cell cultures (i.e. lack of relevant architectural features) and very few have developed 3D cell culture methods for peripheral nerve studies. Therefore, the
Daud, Muhammad Fauzi
core   +6 more sources

A United Kingdom survey of surgical technique and handling practice of inguinal canal structures during hernia surgery [PDF]

, 2006
Background: Recent trials have assessed the impact of elective nerve division on patient outcome after inguinal herniorrhaphy. The aim of this study was to establish UK surgical practice of handling of structures in the inguinal canal during ...
King, Peter M., Debnath, Debasish, Bruce, Julie, Poobalan, Amudha, Ravindran, Rajan   +4 more
core   +3 more sources

Analysis of the C/EBP family of transcription factors in neuronal repair [PDF]

, 2009
PhDNeurons within the peripheral nervous system (PNS) have a remarkable ability to repair themselves after injury; however, neurons within the central nervous system (CNS) do not spontaneously regenerate.
López de Heredia, Luis
core   +4 more sources

Mechanistic Role of Reactive Oxygen Species and Therapeutic Potential of Antioxidants in Denervation- or Fasting-Induced Skeletal Muscle Atrophy

Frontiers in Physiology, 2018
Skeletal muscle atrophy occurs under various conditions, such as disuse, denervation, fasting, aging, and various diseases. Although the underlying molecular mechanisms are still not fully understood, skeletal muscle atrophy is closely associated with ...
Jiaying Qiu, Qingqing Fang, Tongtong Xu, Changyue Wu, Lai Xu, Lingbin Wang, Xiaoming Yang, Shu Yu, Qi Zhang, Fei Ding, Hualin Sun   +10 more
doaj   +1 more source

The Effect of Schwann Cells/Schwann Cell-Like Cells on Cell Therapy for Peripheral Neuropathy

Frontiers in Cellular Neuroscience, 2022
Peripheral neuropathy is a common neurological issue that leads to sensory and motor disorders. Over time, the treatment for peripheral neuropathy has primarily focused on medications for specific symptoms and surgical techniques.
Qian Wang, Fang-Yu Chen, Zhuo-Min Ling, Wen-Feng Su, Ya-Yu Zhao, Gang Chen, Gang Chen, Gang Chen, Zhong-Ya Wei   +8 more
doaj   +1 more source

Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation

Frontiers in Bioengineering and Biotechnology, 2022
Activation of mitophagy was considered to be a potential therapeutic strategy for intervertebral disc degeneration (IDD). There was evidence suggesting that hyaluronic acid (HA) can protect mitochondria from oxidative stress in chondrocytes, but its ...
Fu Zhang, Fu Zhang, Songjuan Wang, Manman Gao, Baoliang Li, Zhongyuan He, Tao Tang, Zhengya Zhu, Shaoyu Liu, Shaoyu Liu, Zhiyu Zhou, Zhiyu Zhou   +11 more
doaj   +1 more source

The success of biomaterial-based tissue engineering strategies for peripheral nerve regeneration

Frontiers in Bioengineering and Biotechnology, 2022
Peripheral nerve injury is a clinically common injury that causes sensory dysfunction and locomotor system degeneration, which seriously affects the quality of the patients’ daily life.
Yuhui Jiang, Yuhui Jiang, Xiaoxuan Tang, Xiaoxuan Tang, Tao Li, Jue Ling, Yumin Yang, Yumin Yang   +7 more
doaj   +1 more source

Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells

Frontiers in Cellular Neuroscience, 2021
Reactive astrogliosis is a key hallmark of inflammatory responses in the pathogenesis of brain injury, including Parkinson’s disease (PD), but its role and regulatory mechanisms are not fully understood.
Zhuo-Min Ling, Zhuo-Min Ling, Qian Wang, Yu Ma, Peng Xue, Yun Gu, Mao-Hong Cao, Mao-Hong Cao, Zhong-Ya Wei   +8 more
doaj   +1 more source

Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis

Frontiers in Molecular Biosciences, 2023
Background: Intervertebral disc degeneration (IDD) is the leading cause of lower back pain, and an overall understanding of the molecular mechanisms related to IDD is still lacking. The purpose of this study was to explore gene signatures and immune cell
Tao Tang, Tao Tang, Zhongyuan He, Zhongyuan He, Zhengya Zhu, Fuan Wang, Fuan Wang, Hongkun Chen, Fu Zhang, Jiaxiang Zhou, Jianmin Wang, Baoliang Li, Baoliang Li, Xizhe Liu, Zhiyu Zhou, Zhiyu Zhou, Shaoyu Liu, Shaoyu Liu   +17 more
doaj   +1 more source

Neuron-autonomous transcriptome changes upon ischemia/reperfusion injury

Scientific Reports, 2017
Ischemic stroke and the following reperfusion, an acute therapeutic intervention, can cause irreversible brain damages. However, the underlying pathological mechanisms are still under investigation.
Jinlong Shi, Xia Chen, Haiying Li, Youjia Wu, Shouyan Wang, Wei Shi, Jian Chen, Yaohui Ni   +7 more
doaj   +1 more source