Results 11 to 20 of about 1,101,918 (298)

An organized 3D in vitro model for peripheral nerve studies [PDF]

, 2013
Three-dimensional cell cultures have been proposed to address the limitations in two-dimensional cell cultures (i.e. lack of relevant architectural features) and very few have developed 3D cell culture methods for peripheral nerve studies. Therefore, the
Daud, Muhammad Fauzi
core   +6 more sources

A United Kingdom survey of surgical technique and handling practice of inguinal canal structures during hernia surgery [PDF]

, 2006
Background: Recent trials have assessed the impact of elective nerve division on patient outcome after inguinal herniorrhaphy. The aim of this study was to establish UK surgical practice of handling of structures in the inguinal canal during ...
King, Peter M., Debnath, Debasish, Bruce, Julie, Poobalan, Amudha, Ravindran, Rajan   +4 more
core   +3 more sources

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach

Journal of Analytical Methods in Chemistry, 2022
Diosgenin, a steroidal sapogenin, has attracted attention worldwide owing to its pharmacological properties, including antitumor, cardiovascular protective, hypolipidemic, and anti-inflammatory effects.
Pei Liu, Lin Xu, Jing-han Guo, Jin-hua Chang, Xi-gang Liu, He-fei Xue, Ru-xing Wang, Zhong-si Li, Guang-xin Miao, Cui-zhe Liu, Jian-yu Zhou   +10 more
doaj   +1 more source

Characterization of circular RNAs in dorsal root ganglia after central and peripheral axon injuries

Frontiers in Cellular Neuroscience, 2022
In central nervous system, axons fail to regenerate after injury while in peripheral nervous system, axons retain certain regenerative ability. Dorsal root ganglion (DRG) neuron has an ascending central axon branch and a descending peripheral axon branch
Hong-Jun Cao, Li Huang, Meng-Ru Zheng, Tao Zhang, Ling-Chi Xu   +4 more
doaj   +1 more source

The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration

Molecular Medicine, 2023
Background Myelin sheath is a crucial accessory to the functional nerve-fiber unit, its disruption or loss can lead to axonal degeneration and subsequent neurodegenerative diseases (NDs).
Jinghui Xu, Bin Zhang, Jieyi Cai, Qianqian Peng, Junxia Hu, Parizat Askar, Jianghong Shangguan, Wenfeng Su, Changlai Zhu, Hualin Sun, Songlin Zhou, Gang Chen, Xiaoming Yang, Yun Gu   +13 more
doaj   +1 more source

Progress in methods for evaluating Schwann cell myelination and axonal growth in peripheral nerve regeneration via scaffolds

Frontiers in Bioengineering and Biotechnology, 2023
Peripheral nerve injury (PNI) is a neurological disorder caused by trauma that is frequently induced by accidents, war, and surgical complications, which is of global significance.
Jue Ling, Chang He, Shuxuan Zhang, Yahong Zhao, Meifeng Zhu, Xiaoxuan Tang, Qiaoyuan Li, Liming Xu, Yumin Yang   +8 more
doaj   +1 more source

Pure-silk fibroin hydrogel with stable aligned micropattern toward peripheral nerve regeneration

Nanotechnology Reviews, 2021
Successful repair of long-distance peripheral nerve injuries remains a challenge in the clinic. Rapid axon growth is a key to accelerate nerve regeneration.
Gu Xinyi, Chen Xiaoli, Tang Xiaoxuan, Zhou Zhihao, Huang Tingting, Yang Yumin, Ling Jue   +6 more
doaj   +1 more source

Light-Triggered Adhesive Silk-Based Film for Effective Photodynamic Antibacterial Therapy and Rapid Hemostasis

Frontiers in Bioengineering and Biotechnology, 2022
Successful control of massive hemorrhage in deep wounds with irregular shape and low elasticity still remains great challenges in the clinic. As the wound sites are usually at risk of bacterial infection, it is necessary to design an ideal hemostatic ...
Tingting Huang, Zhihao Zhou, Qiaoyuan Li, Xiaoxuan Tang, Xiaoxuan Tang, Xiaoli Chen, Yifan Ge, Jue Ling   +7 more
doaj   +1 more source

Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses

Journal of Neuroinflammation, 2022
Background Neuropathic pain is still a challenge for clinical treatment as a result of the comprehensive pathogenesis. Although emerging evidence demonstrates the pivotal role of glial cells in regulating neuropathic pain, the role of Schwann cells and ...
Qian Wang, Han-yang Li, Zhuo-min Ling, Gang Chen, Zhong-Ya Wei   +4 more
doaj   +1 more source

Regenerative Role of T Cells in Nerve Repair and Functional Recovery

Frontiers in Immunology, 2022
The immune system is essential in the process of nerve repair after injury. Successful modulation of the immune response is regarded as an effective approach to improving treatment outcomes.
Xiaoxuan Tang, Xiaoxuan Tang, Qiaoyuan Li, Tingting Huang, Han Zhang, Xiaoli Chen, Jue Ling, Yumin Yang   +7 more
doaj   +1 more source