Results 111 to 120 of about 1,101,918 (298)

A causal examination of the correlation between hormonal and reproductive factors and low back pain

Frontiers in Endocrinology
BackgroundThe relationship between hormonal fluctuations in the reproductive system and the occurrence of low back pain (LBP) has been widely observed. However, the causal impact of specific variables that may be indicative of hormonal and reproductive ...
Dafu Chen, Jiaxiang Zhou, Chengkai Lin, Junhong Li, Zhengya Zhu, Xuezhi Rao, Jianmin Wang, Jianfeng Li, Hongkun Chen, Fuan Wang, Xianlong Li, Manman Gao, Manman Gao, Manman Gao, Manman Gao, Zhiyu Zhou, Zhiyu Zhou, Yongming Xi, Shufen Li   +18 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Outcomes of trigeminal nerve repair

, 2013
This chapter describes the outcomes of trigeminal nerve repair at two European centres, one in Sheffield, UK, and the other in Copenhagen, Denmark, and compares results with those reported in the published literature.
Peter P. Robinson, Keith G. Smith, Hillerup, Søren, Smith, Keith G., Søren Hillerup, Robinson, Peter P.   +5 more
core   +1 more source

Skin derived precursors induced Schwann cells mediated tissue engineering-aided neuroregeneration across sciatic nerve defect

Bioactive Materials
A central question in neural tissue engineering is how the tissue-engineered nerve (TEN) translates detailed transcriptional signals associated with peripheral nerve regeneration into meaningful biological processes.
Chengbin Xue, Hui Zhu, Hongkui Wang, Yaxian Wang, Xi Xu, Songlin Zhou, Dong Liu, Yahong Zhao, Tianmei Qian, Qi Guo, Jin He, Kairong Zhang, Yun Gu, Leilei Gong, Jian Yang, Sheng Yi, Bin Yu, Yongjun Wang, Yan Liu, Yumin Yang, Fei Ding, Xiaosong Gu   +21 more
doaj   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Progress of nerve bridges in the treatment of peripheral nerve disruptions

, 2016
Qiang Ao Department of Tissue Engineering, School of Fundamental Science, China Medical University, Shenyang, Liaoning, Peoples’ Republic of China Abstract: Clinical repair of a nerve defect is one of the most challenging surgical problems ...
Ao Q
core  

A Biological Tube Technique For The Repair Of Peripheral Nerve Defects Using ‘Stuffed Nerves’

, 2016
BACKGROUND: Presently described is research examining the "stuffed nerve" technique to repair peripheral nerve ...
Ergur, Bekir Ugur, Bacakoglu, Ali Abdulkadir, Capkin, Sercan, Akhisaroglu, Mustafa, Sercan ÇAPKIN   +4 more
core   +1 more source

A repeated strike loading organ culture model for studying compression-associated chronic disc degeneration

Biomolecules & Biomedicine
Mechanical stress has been viewed as one of the key risk factors in accelerating the intervertebral disc degeneration process. The goal of the present study was to employ a repeated strike loading bovine caudal disc system to elucidate the ...
Baoliang Li, Xu Chen, Hongkun Chen, Fu Zhang, Jianfeng Li, Zhengya Zhu, Tao Tang, Manman Gao, Nianhu Li, Liang Ma, Zhiyu Zhou   +10 more
doaj   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source