Results 101 to 110 of about 1,101,918 (298)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Bioactive Silk‐Based Nerve Guidance Conduits for Augmenting Peripheral Nerve Repair

, 2018
Repair of peripheral nerve injuries depends upon complex biology stemmingfrom the manifold and challenging injury-healing processes of the peripheralnervous system.
Adrián Magaz, Li, Xu, Faroni, Alessandro; id_orcid, Jonny J. Blaker, Julie E. Gough, Alessandro Faroni, Gough, Julie E.; id_orcid, Adam J. Reid, Reid, Adam J.; id_orcid, Blaker, Jonny J., Magaz, Adrián, Xu Li   +11 more
core   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

An in Vivo Study of Tricalcium Phosphate and Glutaraldehyde Crosslinking Gelatin Conduits in Peripheral Nerve Repair

, 2009
In order to modulate the mechanical properties of gelatin, we previously developed a biodegradable composite composed by tricalcium phosphate and glutaraldehyde crosslinking gelatin (GTG) feasible for surgical manipulation.
陳敏弘;陳美秀;謝松蒼;黃金山;林峰輝, CHEN, MING-HONG;CHEN, MEI-HSIU;HSIEH, SUNG-TSANG;HUANG, JING-SHAN;LIN, FENG- HUEI   +1 more
core  

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Advanced Nanoparticle-Engineered Platforms for Peripheral Nerve Repair: Multimodal Therapeutic Strategies and Clinical Translation [PDF]

Shaoyan Shi,1 Xingxing Yu,2 Xuehai Ou,1 Changming Zheng,1 Fei Xie,1 Yansheng Huang3 1Department of Hand Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, 710000, People’s Republic of China; 2Department of Laboratory Medicine, Xi’ an ...
Xie F, Huang Y, Shi S, Zheng C, Ou X, Yu X   +5 more
core  

Sense and Sensibility: Nerve Tape—A More Efficient Alternative for Nerve Repair in Breast Reconstruction?

Background:. Current methods of nerve coaptation, ranging from epineural microsuture to fibrin glue, are either technically challenging or inadequate in providing robust repair.
Lisa Gfrerer, MD, PhD, Hao Huang, MD, Malini Chinta, MD, Theresa Webster, MD   +3 more
core   +1 more source

Nerve Repair Chamber

, 2022
Peripheral nerve injury can lead to severe loss of motor control or sensory integration, posing a significant decrement to quality of life. Yet, using traditional approaches to repair, maximal recovery can take up to 2-3 years to achieve with fewer than ...
Bronk, Theodore, Campbell, Gracyn, Choudhury, Reeham, Xia, Yutong (Linda), Montagnese, Basile, De La Cruz, Joshua   +5 more
core  

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Correction: Comparative intra- and inter-observer reliability of two methods for evaluating intraoperative ultrasonography-based spinal cord hyperechogenicity intensity in degenerative cervical myelopathy

BMC Musculoskeletal Disorders, 2022
Huachuan Wu, Guoliang Chen, Xianlong Li, Zhengya Zhu, Zuofeng Xu, Xizhe Liu, Shaoyu Liu   +6 more
doaj   +1 more source