Results 91 to 100 of about 157,358 (309)

Peripheral Facial Nerve Axotomy in Mice Causes Sprouting of Motor Axons Into Perineuronal Central White Matter: Time Course and Molecular Characterization

, 2010
Generation of new axonal sprouts plays an important role in neural repair In the current study, we examined the appearance, composition and effects of gene deletions on intrabrainstem sprouts following peripheral facial nerve axotomy Axotomy was followed
Werner, A, Galiano, Mathias, Ruff, Crystal, Mathias Galiano, Werner, A., Gonitel, R, Werner, Alexander, Anderson, P., Raivich, G., Patrick N. Anderson, Prakasham Rumajogee, Pararajasingam, A, Bohatschek, M, Behrens, A, Galiano, M., Cuthill, Dan, Bohatschek, M., Acosta-Saltos, A, Makwana, Milan, Dan Cuthill, Rumajogee, P., Anderson, Patrick N., Wallace, A. S., Ulrike Mayer, Acosta-Saltos, Alejandro, Anderson, PN, Behrens, Axel, Raivich, Gennadij, Pararajasingham, A, Gonitel, R., Anderson, P. N., Rumajogee, Prakasham, Ruff, C., Ruff, C, Rumajogee, P, Wallace, AS, Acosta-Saltos, A., Alejandro Acosta‐Saltos, Marion Bohatschek, Axel Behrens, Makwana, M, Wallace, Adam S., Bohatschek, Marion, Gennadij Raivich, Mayer, U, Mayer, Ulrike, Wallace, A., Alexander Werner, Adam S. Wallace, Pararajasingham, Abirami, Behrens, A., Abirami Pararajasingham, Makwana, M., Cuthill, D., Crystal Ruff, Cuthill, D, Galiano, M, Gonitel, Roman, Roman Gonitel, Mayer, U., Milan Makwana, Pararajasingham, A., Raivich, G   +62 more
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Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Melatonin and sciatic nerve injury repair: a current perspective

, 2018
Berrin Zuhal Altunkaynak,1 Burcu Delibaş,2 Gamze Altun,2 Ömür Gülsüm Deniz2 1Department of Histology and Embryology, Medical Faculty, Okan University, Istanbul; Turkey; 2Department of Histology and Embryology, Medical Faculty, Ondokuz
Altun G, Altunkaynak BZ, Deniz ÖG, Delibaş B   +3 more
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Outcomes of trigeminal nerve repair

, 2013
This chapter describes the outcomes of trigeminal nerve repair at two European centres, one in Sheffield, UK, and the other in Copenhagen, Denmark, and compares results with those reported in the published literature.
Peter P. Robinson, Keith G. Smith, Hillerup, Søren, Smith, Keith G., Søren Hillerup, Robinson, Peter P.   +5 more
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Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Hand function after nerve repair [PDF]

, 2020
Treatment of injuries to major nerve trunks in the hand and upper extremity remains a major and challenging reconstructive problem. Such injuries may cause long-lasting disabilities in terms of lost fine sensory and motor functions.

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Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells

Frontiers in Molecular Neuroscience, 2018
Although there are available therapies as surgery, chemotherapy and radiation, glioblastoma (GBM) still has been considered as the most common and overwhelming primary tumor of brain. In GBM, the brain glioma stem cells (BGSCs) were identified and played
Hui Zhu, Hui Zhu, Hongkui Wang, Qingfeng Huang, Qianqian Liu, Qianqian Liu, Yibing Guo, Jingjing Lu, Xiaohong Li, Chengbin Xue, Chengbin Xue, Qianqian Han   +11 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Analysis of the C/EBP family of transcription factors in neuronal repair

, 2009
PhDNeurons within the peripheral nervous system (PNS) have a remarkable ability to repair themselves after injury; however, neurons within the central nervous system (CNS) do not spontaneously regenerate.
López de Heredia, Luis
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