Results 81 to 90 of about 311,832 (302)

DLX5 regulates the osteogenic differentiation of spinal ligaments cells derived from ossification of the posterior longitudinal ligament patients via NOTCH signaling

JOR Spine, 2023
Background Ossification of the posterior longitudinal ligaments (OPLL) is common disorder characterized by heterotopic ossification of the spinal ligaments. Mechanical stimulation (MS) plays an important role in OPLL.
Tao Tang, Zhengya Zhu, Zhongyuan He, Fuan Wang, Hongkun Chen, Shengkai Liu, Mingbin Zhan, Jianmin Wang, Wei Tian, Dafu Chen, Xinbao Wu, Xizhe Liu, Zhiyu Zhou, Shaoyu Liu   +13 more
doaj   +1 more source

Identification of Regulatory Factors and Prognostic Markers in Amyotrophic Lateral Sclerosis

Antioxidants, 2022
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle atrophy, paralysis and even death.
Hualin Sun, Ming Li, Yanan Ji, Jianwei Zhu, Zehao Chen, Lilei Zhang, Chunyan Deng, Qiong Cheng, Wei Wang, Yuntian Shen, Dingding Shen   +10 more
doaj   +1 more source

Medical implantable devices for the controlled release of anti-TGF-beta1 in the repair of peripheral nerve injuries [PDF]

, 2004
The development of novel bioartificial nerve grafts which release soluble therapeutic agents, shows great promises guiding the extension of the injured axons and optimizing and improving the degree and specificity of neural outgrowth.
Brown, R.A., Caneva Soumetz, F., Giacomini, M., Phillips, J.B., Ruggiero, C.   +4 more
core  

Rare Complications of Cervical Spine Surgery: Pseudomeningocoele. [PDF]

, 2017
STUDY DESIGN: This study was a retrospective, multicenter cohort study. OBJECTIVES: Rare complications of cervical spine surgery are inherently difficult to investigate.
Ailon, Tamir, Arnold, Paul M., Buser, Zorica, Chou, Dean, Corriveau, Mark, Fehlings, Michael G., Fish, David E., Hilibrand, Alan S., Hsu, Wellington K., Lee, Sungho, Lord, Elizabeth L L., Massicotte, Eric M., Mroz, Thomas E., Mummaneni, Praveen V., Nassr, Ahmad, Pace, Jonathan, Riew, K. Daniel, Sasso, Rick C., Sebastian, Arjun S., Shaffrey, Christopher, Smith, Gabriel A., Smith, Justin S., Smith, Zachary A., Steinmetz, Michael P., Than, Khoi D., Traynelis, Vincent C., Wang, Jeffrey C.   +26 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Flavonoids: a natural remedy in the prevention and management of diverse diseases

Frontiers in Medicine
BackgroundFlavonoids, which fall into the polyphenol family as secondary metabolites, can be widely found in traditional Chinese herbal medicines. Owing to their multi-target characteristics, low toxicity levels, and diverse sources, flavonoids have ...
Bo Yu, Jin Zhang, Mengxuan Zhu, Zongwu Li, Liqun Ren, Fan Zhang, Cuizhe Liu, Lin Zhang   +7 more
doaj   +1 more source

Vagus nerve stimulation paired with tactile training improved sensory function in a chronic stroke patient [PDF]

, 2018
Background: Recent studies indicate that vagus nerve stimulation (VNS) paired with rehabilitation can enhance neural plasticity in the primary sensory and motor cortices, improve forelimb function after stroke in animal models and improve motor function ...
Alexander, Jen, Dawson, Jesse, Kilgard, Michael P., Rennaker, Robert L.   +3 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons [PDF]

, 2003
Transplantation of olfactory ensheathing cells into spinal cord lesions promotes regeneration of cut axons into terminal fields and functional recovery.
Li, D., Li, Y., Lund, R.D., Raisman, G., Sauvé, Y.   +4 more
core  

ATP Released by Injured Neurons Activates Schwann Cells [PDF]

, 2016
Injured nerve terminals of neuromuscular junctions (NMJs) can regenerate. This remarkable and complex response is governed by molecular signals that are exchanged among the cellular components of this synapse: motor axon nerve terminal (MAT ...
Cesare eMontecucco, Cesare eMontecucco, Elisa eDuregotti, Elisanna eBergamin, Kees eJalink, Michela eRigoni, Michele eScorzeto, Samuele eNegro, Umberto eRodella   +8 more
core   +2 more sources