Gpr126/Adgrg6 has Schwann cell autonomous and nonautonomous functions in peripheral nerve injury and repair [PDF]
Schwann cells (SCs) are essential for proper peripheral nerve development and repair, although the mechanisms regulating these processes are incompletely understood.
Carlin, Dan +8 more
core +2 more sources
Skeletal muscle atrophy occurs under various conditions, such as disuse, denervation, fasting, aging, and various diseases. Although the underlying molecular mechanisms are still not fully understood, skeletal muscle atrophy is closely associated with ...
Jiaying Qiu +10 more
doaj +1 more source
Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation
Activation of mitophagy was considered to be a potential therapeutic strategy for intervertebral disc degeneration (IDD). There was evidence suggesting that hyaluronic acid (HA) can protect mitochondria from oxidative stress in chondrocytes, but its ...
Fu Zhang +11 more
doaj +1 more source
A United Kingdom survey of surgical technique and handling practice of inguinal canal structures during hernia surgery [PDF]
Background: Recent trials have assessed the impact of elective nerve division on patient outcome after inguinal herniorrhaphy. The aim of this study was to establish UK surgical practice of handling of structures in the inguinal canal during ...
Bruce, Julie +4 more
core +1 more source
A 3D‐Printed Self‐Adhesive Bandage with Drug Release for Peripheral Nerve Repair
Peripheral nerve injury is a common disease that often causes disability and challenges surgeons. Drug‐releasable biomaterials provide a reliable tool to regulate the nerve healing‐associated microenvironment for nerve repair.
Jiumeng Zhang +10 more
semanticscholar +1 more source
The success of biomaterial-based tissue engineering strategies for peripheral nerve regeneration
Peripheral nerve injury is a clinically common injury that causes sensory dysfunction and locomotor system degeneration, which seriously affects the quality of the patients’ daily life.
Yuhui Jiang +7 more
doaj +1 more source
Estimations of topographically correct regeneration to nerve branches and skin after peripheral nerve injury and repair. [PDF]
Peripheral nerve injury is typically associated with long-term disturbances in sensory localization, despite nerve repair and regeneration. Here, we investigate the extent of correct reinnervation by back-labeling neuronal soma with fluorescent tracers ...
Molander, Carl +2 more
core +2 more sources
Astrocyte Pannexin 1 Suppresses LPS-Induced Inflammatory Responses to Protect Neuronal SH-SY5Y Cells
Reactive astrogliosis is a key hallmark of inflammatory responses in the pathogenesis of brain injury, including Parkinson’s disease (PD), but its role and regulatory mechanisms are not fully understood.
Zhuo-Min Ling +8 more
doaj +1 more source
Polymer- and Hybrid-Based Biomaterials for Interstitial, Connective, Vascular, Nerve, Visceral and Musculoskeletal Tissue Engineering [PDF]
In this review, materials based on polymers and hybrids possessing both organic and inorganic contents for repairing or facilitating cell growth in tissue engineering are discussed.
Abalymov, Anatolii +2 more
core +1 more source
3D Printed Personalized Nerve Guide Conduits for Precision Repair of Peripheral Nerve Defects
The treatment of peripheral nerve defects has always been one of the most challenging clinical practices in neurosurgery. Currently, nerve autograft is the preferred treatment modality for peripheral nerve defects, while the therapy is constantly plagued
Kai Liu +6 more
semanticscholar +1 more source

