Results 11 to 20 of about 1,193,059 (373)
Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms [PDF]
Frontiers in Molecular NeuroscienceIntroductionSciatica is a prevalent and highly debilitating condition that is clinically characterized by pain radiating along the distribution of the sciatic nerve.
Xingjuan Li +7 more
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Immunohistochemical localization of nerve injury-induced protein-1 in mouse tissues [PDF]
Anatomy & Cell Biology, 2019 Nerve injury-induced protein (Ninjurin)-1 is a cell adhesion molecule that is upregulated in neurons and Schwann cells after transection injury in rats. In this study, we investigated the localization of Ninjurin-1 in various tissues, including the cerebrum, sciatic nerve, spleen, lung, stomach, ileum, colon, liver, pancreas, kidney, testis, and skin ...
Poornima D. E. Weerasinghe-Mudiyanselage +4 more
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Translational MedicineBackground. For preclinical studies of drugs a relevant task is the selection of specific biochemical markers reflecting damage to the central nervous system, both in toxicological and pharmacological experiments. One of such markers may be protein S100b, the level of which will make it possible to assess the damage of the central nervous system of ...
V. A. Vavilova +5 more
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Recovery of sweet taste preference in adult rats following bilateral chorda tympani nerve transection [PDF]
PeerJ, 2022 Background Numerous studies have noted the effect of chorda tympani (CT) nerve transection on taste sensitivity yet very few have directly observed its effects on taste receptor and taste signaling protein expressions in the tongue tissue.
Andrew Padalhin +7 more
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Transection injury differentially alters the proteome of the human sural nerve
PLoS ONE, 2022 Regeneration after severe peripheral nerve injury is often poor. Knowledge of human nerve regeneration and the growth microenvironment is greatly lacking.
Monica J. Chau +7 more
doaj +2 more sources
Theranostics, 2023 Severe injuries or diseases affecting the peripheral and central nervous systems can result in impaired organ function and permanent paralysis. Conventional interventions, such as drug administration and cell-based therapy, exhibit limited effectiveness ...
semanticscholar +1 more source
Cell Transplantation, 2022 One promising strategy in cell therapies for Parkinson’s disease (PD) is to harness a patient’s own cells to provide neuroprotection in areas of the brain affected by neurodegeneration. No treatment exists to replace cells in the brain.
Monica J. Chau +6 more
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Induction of ectopic retina-like tissue by transgenic expression of neurogenin. [PDF]
PLoS ONE, 2015 Degeneration of retinal neurons is an underlying cause of several major types of blinding diseases, and effective therapies remain to be developed. The suppositive strategy of repopulating a degenerative retina with new cells generated onsite faces ...
Run-Tao Yan +3 more
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Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates [PDF]
, 2020 Perturbations in skeletal muscle metabolism have been reported for a variety of neuromuscular diseases. However, the role of metabolism after constriction injury to a nerve and the associated muscle atrophy is unclear.
Afzal, Shoaib +3 more
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Brain and Behavior, 2020 Introduction Posttraumatic scarring of peripheral nerves produces unwanted adhesions that block axonal growth. In the context of surgical nerve repair, the organization of the scar tissue adjacent to conduits used to span the gap between the stumps of ...
Jolanta Fertala +5 more
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