Results 71 to 80 of about 375,080 (241)

TGF-beta(2)- and H2O2-Induced Biological Changes in Optic Nerve Head Astrocytes Are Reduced by the Antioxidant Alpha-Lipoic Acid [PDF]

, 2012
Background/Aims: The goal of the present study was to determine whether transforming growth factor-beta(2) (TGF-beta(2))- and oxidative stress-induced cellular changes in cultured human optic nerve head (ONH) astrocytes could be reduced by pretreatment ...
Abdul HM, Alice L. Yu, Aslan M, Bilska A, Buniatian GH, Cabell L, Carini M, Chong MS, Esposito G, Fuchshofer R, Fuchshofer R, Fukuchi T, Furuyoshi N, Gaitanaki C, Hatten ME, He S, Hernandez MR, Hernandez MR, Hernandez MR, Hernandez MR, Hodges NJ, Ihnat MA, Izzotti A, Jerome Moriniere, Kobayashi S, Kumar DM, Lambert W, Louhelainen M, Lutjen-Drecoll E, Malone PE, Markesbery WR, Meldrum B, Mozaffarieh M, Neufeld AH, Neumann C, Ohia SE, Oksala NK, Oksala NK, Pena JD, Picht G, Proell V, Ridet JL, Sacca SC, Salinthone S, Samali A, Sharp FR, Shin JH, Smith AR, Sturrock A, Tezel G, Tezel G, Tripathi RC, Ulrich Welge-Lussen, Valencia A, Veach J, Várkonyi T, Yang KL, Yang P, Yu AL, Yu AL, Zimmer DB   +60 more
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Studies on cultured Schwann cells: the induction of myelin synthesis, and the control of their proliferation by a new growth factor [PDF]

, 1981
We have recently described the use of immunological methods to identify and purify rat Schwann cells. In dissociated cultures of neonatal sciatic nerve, all of the cells can be identified by antigenic criteria as either Schwann cells or fibroblasts.
Brockes, J. P., Fryxell, K. J., Lemke, G. E.   +2 more
core  

Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability [PDF]

, 2018
Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum disorders, in which sensory dysfunction is increasingly recognized.
Bennett, David L., Buckley, Camilla, Carroll, Liam, Cervellini, Ilaria, Chisholm, Kim I., Clark, Alex J, Coutinho, Ester, Dawes, John M., Dickenson, Anthony H., Galino, Jorge, Giannoccaro, Maria Pia, Gutierrez-Mecinas, Maria, Iwagaki, Noboru, Jacobson, Leslie, Kuehn, Hannah, Kühnemund, Johannes, Lang, Bethan, Leite, M Isabel, Lewin, Gary R., McMahon, Stephen B., Menassa, David A., Middleton, Steven J., Patel, Ryan, Peck, Liam J., Peles, Elior, Pettingill, Philippa, Sanna, Maria D., Shakir, Akila, Sheridan, Joseph, Tewari, Damini, Themistocleous, Andreas C., Todd, Andrew J., Trendafilova, Teodora, Vincent, Angela, Walcher, Jan, Weir, Greg A., Werynska, Karolina, West, Steven J., Wildner, Hendrik, Zeilhofer, Hanns Ulrich   +39 more
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Expression and significance of Ninj1, IL-1β and PGP-9.5 in ectopic endometrial tissues of patients with endometriosis [PDF]

精准医学杂志
Objective To investigate the expression levels of nerve injury-induced protein 1 (Ninjl), interleukin-1β(IL-1β), and protein gene product 9.5 (PGP-9.5) in the ectopic endometrial tissues of patients with endometriosis (EMT) and their relationship with ...
ZHAO Li, LI Yuying, WANG Lei, JIAO Jinwen, SUN qi, HUANG Meisha, YUAN Fang
doaj   +1 more source

Research and application of stem cell-derived exosomes in regenerative medicine

口腔疾病防治, 2020
Stem cells are a class of undifferentiated cells with high self-renewal and rapid proliferative capabilities. Undercertain conditions, stem cells can induce differentiation into other tissue cells of the human body, such as skeletal muscle cells ...
YE Qingsong, HU Fengting, LUO Lihua, Maria Troulis   +3 more
doaj   +1 more source

Neurotoxicity [PDF]

, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust, Creeley, Feldman, Grandjean, Herken, Panzica, Parent, Pessah, Rice, Román, Spencer, Spencer, Tu, Vinken, Yasui, Zawia   +15 more
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Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior [PDF]

, 2006
The S100 family protein p11 (S100A10, annexin 2 light chain) is involved in the trafficking of the voltage-gated sodium channel Na(V)1.8, TWIK-related acid-sensitive K+ channel (TASK-1), the ligand-gated ion channels acid-sensing ion channel 1a (ASIC1a ...
Baker, MD, Dickenson, AH, Foulkes, T, Gerke, V, Lane, T, Matthews, EA, Nassar, MA, Okuse, K, Wood, JN   +8 more
core   +1 more source

Evaluating techniques in tissue clarification using CLARITY imaging and investigating where sodium is sensed in the body [PDF]

, 2016
OBJECTIVE: Previous studies have shown the significant contribution of sympathoinhibition in response to sodium loading to prevent increases in mean arterial blood pressure in salt resistant phenotypes.
Neal, Christopher Matthew
core   +1 more source

Melting transitions in biomembranes

, 2019
We investigated melting transitions in biological membranes in their native state that include their membrane proteins. These membranes originated from \textit{E. coli}, \textit{B.
Heimburg, Thomas, Konrad, Manfred, Madsen, Soren B., Music, Tea, Pollakowski, Denis, Tounsi, Fatma   +5 more
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Oral Inflammation, Tooth Loss, Risk Factors, and Association with Progression of Alzheimer’s Disease [PDF]

, 2014
Periodontitis is a polymicrobial chronic inflammatory disease of tooth-supporting tissues with bacterial etiology affecting all age groups, becoming chronic in a subgroup of older individuals.
Crean, Stjohn, Harding, Alice, Kesavalu, Lakshmyya, Robinson, Sarita Jane, Simmons, Tal, Singhrao, Simarjit Kaur   +5 more
core   +1 more source