Results 71 to 80 of about 1,193,059 (373)
The landscape of expression and alternative splicing variation across human traits
Cell Genomics, 2023 Summary: Understanding the consequences of individual transcriptome variation is fundamental to deciphering human biology and disease. We implement a statistical framework to quantify the contributions of 21 individual traits as drivers of gene ...
Raquel García-Pérez +15 more
doaj +1 more source
The Effect of Vincristine Sulphate on the Axoplasmic Flow of Proteins in Cultured Sympathetic Neurons [PDF]
, 1973 The effect of vincristine sulphate on the axoplasmic flow of labelled proteins in neurites of chick embryo sympathetic neurons growing in tissue culture was studied by autoradiography.
England, J. M. +2 more
core
Components of cell-matrix linkage as potential new markers for prostate cancer [PDF]
, 2011 Prostate cancer is one of the most common tumor diseases worldwide. Often being non-aggressive, prostate tumors in these cases do not need immediate treatment.
Eble, Johannes Andreas, Navdaev, Alexey
core +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal
Journal of Neuroscience, 1988 We used an antiserum against purified cholinergic synaptic vesicles from Torpedo and expression screening to isolate a cDNA clone encoding synuclein, a 143 amino acid neuron-specific protein.
L. Maroteaux, JT Campanelli, R. Scheller
semanticscholar +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The Ultrastructure of Tissue Damage by Amyloid Fibrils
Molecules, 2021 Amyloidosis is a group of diseases that includes Alzheimer’s disease, prion diseases, transthyretin (ATTR) amyloidosis, and immunoglobulin light chain (AL) amyloidosis.
Haruki Koike, Masahisa Katsuno
doaj +1 more source
Angiogenic and Neurotrophic Effects of Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium for Erectile Dysfunction [PDF]
, 2020 Department of Biomedical EngineeringA three-dimensional spheroid culture system to harvest conditioned medium (CM) from human bone marrow-derived mesenchymal stem cells (hBM-MSCs) with high efficiency were introduced and investigated the therapeutic ...
Kim, Seul Gi
core
Nondirected axonal growth on basal lamina from avian embryonic neural retina [PDF]
, 1987 The vitreous surface of the embryonic avian retinal neuroepithelium was isolated by mechanical disruption of the retina mounted between 2 adhesive substrata.
Halfter, W. +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source