Results 101 to 110 of about 2,544,571 (298)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Periocular motor neurotization: a systematic review of techniques and outcomes in orbicularis oculi reinnervation

open access: yesFrontiers in Ophthalmology
BackgroundPeriocular motor neurotization is a surgical approach that can be indicated for the restoration of dynamic eyelid function in patients with facial nerve palsy. The orbicularis oculi muscle, responsible for eyelid closure, can be the target of a
Abdelrahman Abu Osba   +3 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Sensory restoration of the critical border of the small finger by an emergency heterodigital nerve transfer after circular saw injury

open access: yesActa Marisiensis - Seria Medica
Traumatic nerve injuries involving the distal part of the upper extremity may significantly affect the function of the hand if left untreated. An alternative to nerve autografts for treating digital nerve injuries are nerve transfers.
Ioncioaia Bogdan   +2 more
doaj   +1 more source

Results of finger extension reconstruction in hemiplegic patients after stroke by transferring the flexor carpi radialis branch to the posterior interosseous nerve

open access: yesJournal of Plastic Surgery and Hand Surgery
Purpose: Contralateral C7 nerve transfer (CC7) surgery has demonstrated success in restoring upper limb motor function after central nervous system injuries. However, deficits in finger extension limit patient independence.
Sihan Hu   +7 more
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Investigation of heat transfer augmentation through use of internally finned and roughened tubes : final summary report [PDF]

open access: yes, 1970
This report summarizes a three-year program concerned with obtaining basic design information for tubes having a random roughness on the inside wall (RID) and tubing having continuous internal fins (Forge Fin).
Brown, G. S.   +4 more
core  

DETERMINANTS OF NERVE CONDUCTION RECOVERY AFTER NERVE INJURIES: COMPRESSION DURATION AND NERVE FIBER TYPES

open access: yes, 2017
Introduction: The aims of this study were to determine the influences of: (1) timing of nerve decompression; and (2) nerve fiber types on the patterns of nerve conduction studies (NCS) after nerve injury.
Tseng, To-Jung;Hsiao, Tin-Hsin;Hsieh, Sung-Tsang;Hsieh, Yu-Lin   +1 more
core   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

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