Results 111 to 120 of about 2,544,571 (298)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

The influence of return bends on the downstream pressure drop and condensation heat transfer in tubes [PDF]

, 1971
The influence of return bends on the downstream pressure drop and heat transfer coefficient of condensing refrigerant R-12 was studied experimentally. Flow patterns in glass return bends of 1/2 to 1 in. radius and 0.315 in. I. D.
Traviss, Donald P., Rohsenow, Warren M.
core  

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Utilidad de la transposición nerviosa en el tetrapléjico: Caso clinico

Revista Iberoamericana de Cirugía de la Mano
La lesión medular espinal tiene una incidencia de 40 casos nuevos por millón de habitantes, siendo las regiones más afectadas la columna cervical y lumbar.
Lidia Ledesma Galey, José Manuel Méndez López   +1 more
doaj   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Morphometric analysis of myelinated fibre composition in the optic nerve of adult C57BL and CBA strain mice and (C57BL x CBA) F1 hybrid:a comparison of interstrain variation [PDF]

, 1995
In a study involving 50 optic nerves isolated from 3 different strains of adult male mice, C57BL, CBA and (C57BL x CBA) F1 hybrids, and from adult female CBA strain mice, we observed that the mouse had a lower mean total myelinated nerve fibre count than
Dangata, Y Y, Findlater, G S, Kaufman, M H   +2 more
core  

Chapter 28 future perspective in peripheral nerve reconstruction.

, 2009
Nerve injuries induce severe disability and suffering for patients. Profound alterations in nerve trunks, neurons, and the central nervous system are induced rapidly after injury.
Dahlin, Lars, Martin Kanje, Lars Dahlin, Charlotta Lindwall, Lindwall, Charlotta, Fredrik Johansson, Kanje, Martin, Lindwall, Charlotta,, Johansson, Fredrik   +8 more
core   +1 more source

The role of nerve transfers in chronic nerve compression syndromes

International Orthopaedics
Abstract Purpose Compression neuropathy is a common problem that results in impaired axonal conduction, and with time, numbness, tingling and weakness from muscle atrophy. Supercharge reverse end-to-side (SETS) nerve transfers have emerged as a novel approach to augment function in chronic nerve compression syndromes ...
Kennedy, Patrick J., Nag, Shayoni, Otto-Moudry, Reade, Moore, Amy M.   +3 more
openaire   +2 more sources

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source