Results 51 to 60 of about 3,155,450 (380)

Modeling of interstitial branching of axonal networks [PDF]

open access: yes1. J. Integr. Neurosci. 12, 1-14, (2013), 2013
A single axon can generate branches connecting with plenty synaptic targets. Process of branching is very important for making connections in central nervous system. The interstitial branching along primary axon shaft occurs during nervous system development. Growing axon makes pause in its movement and leaves active points behind its terminal. The new
arxiv   +1 more source

Tertiary lymphoid organs in central nervous system autoimmunity [PDF]

open access: yes, 2016
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy

open access: yesJournal of Nanobiotechnology
Background The Hippo pathway is a conserved tumour suppressor signalling pathway, and its dysregulation is often associated with abnormal cell growth and tumorigenesis.
Ji Qi   +11 more
doaj   +1 more source

Modeling the Nervous System as An Open Quantum System [PDF]

open access: yesarXiv, 2021
We propose a neural network model of multi-neuron interacting system that simulates neurons to interact each other through the surroundings of neuronal cell bodies. We physically model the neuronal cell surroundings, include the dendrites, the axons and the synapses as well as the surrounding glial cells, as a collection of all kinds of oscillating ...
arxiv  

The enteric nervous system [PDF]

open access: yesDevelopmental Biology, 2012
The enteric nervous system (ENS), the intrinsic innervation of the gastrointestinal tract, consists of numerous types of neurons, and glial cells, that are distributed in two intramuscular plexuses that extend along the entire length of the gut and control co-ordinated smooth muscle contractile activity and other gut functions.
Vassilis Pachnis   +2 more
openaire   +2 more sources

Researcher studies nervous system development [PDF]

open access: yes, 2016
Ashley Purdy, who recently finished a master’s degree in biology at VCU and is now pursuing her Ph.D., is studying nerve cells in zebrafish in hopes of unlocking secrets about the human nervous system.
Bellamy, Paige
core   +1 more source

Observation of experimental lathyrism in the rat [PDF]

open access: yes, 1959
The clinical manifestations, roentgenologic studies, and histopathologic findings of the central nervous system of rats with induced lathyrism were described.
Lee, HUN Jae
core   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Phase transition in the economically modeled growth of a cellular nervous system [PDF]

open access: yesProc. Natl. Acad. Sci. USA, 110 (19), 7880-7885 (2013), 2013
Spatially-embedded complex networks, such as nervous systems, the Internet and transportation networks, generally have non-trivial topological patterns of connections combined with nearly minimal wiring costs. However the growth rules shaping these economical trade-offs between cost and topology are not well understood.
arxiv   +1 more source

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