Results 71 to 80 of about 18,915,503 (310)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Primer on the autonomic nervous system /

, 2004
The Primer on the Autonomic Nervous System presents, in a readable and accessible format, key information about how the autonomic nervous system controls the body, particularly in response to stress.
Robertson, David
core  

Drugs and the peripheral nervous system [PDF]

, 2017
Contents\ud \ud 7.1. Drugs and the sympathetic nervous system\ud \ud - 7.1.1 The sympathetic nervous system\ud \ud \ud - 7.1.2 Effects of the sympathetic nervous system\ud \ud \ud - 7.1.3 Sympathomimetics\ud \ud \ud - 7.1.4 Selective α1-adrenoceptor ...
Doggrell, Sheila
core  

Glutathione in the nervous system: Roles in neural function and health and implications for neurological disease

, 2007
The chapter, "Glutathione in the nervous system: Roles in neural function and health and implications for neurological disease" was written by the listed authors including Reyniel Cruz-Aguado (Douglas College Faculty).

core   +1 more source

Factors affecting diagnosis of primary pediatric central nervous system neoplasias in a developing country

, 2020
Understand the variables that could interfere with diagnosis and prompt treatment in CNS childhood cancer in Brazil, a developing country with continental dimensions.MethodsFrom 2005 to 2010, we retrospectively evaluated factors, which could represent a ...
Aguiar, Simone dos Santos, Morcillo, Andre Moreno, Tedeschi, Helder, Ghizoni, Enrico, Gilli, Isadora Olenscki, Joaquim, Andrei Fernandes   +5 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Pseudoneoplasms of the Nervous System

Archives of Pathology & Laboratory Medicine, 2010
Abstract Context. —Pseudoneoplasms of the nervous system vary greatly in nature. Ranging from inflammatory to autoimmune, infectious, malformative, reactive, degenerative, and radiation induced, they all mimic true tumors.
Kliment, Donev, Bernd W, Scheithauer
openaire   +2 more sources

Acute disseminated encephalomyelitis with delayed onset and feasibility of the Miethke shunt and sensor reservoir system : a case report

, 2021
Acute disseminated encephalomyelitis (ADEM) is an immune-mediated demyelinating central nervous system disorder with predilection for early childhood.
Grabowska, A, Petursdottir, Dyrleif, Rostami, E,, Ehrstedt, Christoffer, Grabowska, Anna, Liminga, Gunnar, Ehrstedt, Christoffer,, Petursdottir, D, Grabowska, Anna,, Rostami, Elham,, Ehrstedt, C, Cesarini, KG, Cesarini, Kristina G,, Liminga, Gunnar,, Rostami, Elham, Cesarini, Kristina G, Petursdottir, Dyrleif,, Liminga, G   +17 more
core   +1 more source

TSPO deficiency promotes the progression of malignant peripheral sheath tumors by regulating the G2/M phase of the cell cycle via CDK1

Scientific Reports
Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive Schwann cell-derived sarcomas that are sporadic or associated with Neurofibromatosis 1 (NF1) gene mutations. Traditional therapies are usually ineffective for treating MPNSTs, so new
Xingnan Zhang, Chenhao Hu, Shengqiao Sun, Chao Guo, Yakun Bu, Zicong Wang, Zewei Liu, Xiaoli Zhang, Dezhi Li, Song Liu   +9 more
doaj   +1 more source