Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM) [PDF]
, 2015 Background Trypanosoma cruzi, causative agent of Chagas disease, displays high intraspecific genetic diversity: six genetic lineages or discrete typing units (DTUs) are currently recognized, termed TcI through TcVI.
Bhattacharyya, T. +7 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Jurnal Veteriner, 2017 Legionella pneumophila is a Gram-negative bacillus that causes nosocomial and community-acquired pneumonia. The aim of this research was to detect the presence of bacteria of L.
Eduardus Bimo Aksono +2 more
doaj +1 more source
Molecular characterization of dengue viruses during an outbreak in Kolkata: A hospital-based study
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023 Context: Dengue, a mosquito-borne viral infection in the tropical regions of the world, has recently become a major public health concern. In West Bengal, several outbreaks of dengue fever occurred in the past few years.
Kheya Mukherjee +5 more
doaj +1 more source
Identifikasi Coxiella Brunetii Menggunakan Pengujian Polymerase Chain Reaction pada Kambing di Kota Kupang [PDF]
, 2014 Identification of Coxiella brunetii using polymerase chain reaction method in goats in Kupang area at Nusa Tenggara Timur had been done. Coxiella burnetii as causative of Q fever zoonosis in human and livestock and become public health problem.
Detha, A. I. (Annytha)
core
Multiple human herpesvirus-8 infection [PDF]
, 2003 In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM +7 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Allelic forms of merozoite surface protein-3 in Plasmodium falciparum isolates from southeast of Iran [PDF]
, 2014 Background: Genetic diversity has provided Plasmodium falciparum with the potential capacity of avoiding the immune response, and possibly supported the natural selection of drug or vaccine-resistant parasites.
Ebrahimzadeh, A. +2 more
core +8 more sources
Integrated DNA walking system to characterize a broad spectrum of GMOs in food/feed matrices [PDF]
, 2015 Background: In order to provide a system fully integrated with qPCR screening, usually used in GMO routine analysis, as well as being able to detect, characterize and identify a broad spectrum of GMOs in food/feed matrices, two bidirectional DNA walking ...
De Loose, Marc +6 more
core +6 more sources
Rapid detection of Salmonella in field samples by nested polymerase chain reaction [PDF]
Letters in Applied Microbiology, 1999 A simple and universal protocol for the rapid detection of Salmonella spp. in various samples using nested polymerase chain reaction (PCR) was developed. The protocol takes advantage of the rapid purification and concentration of Salmonella by centrifugation onto a layer of 60% sucrose solution.
I, Rychlík +5 more
openaire +2 more sources