Results 111 to 120 of about 41,897 (208)
Immunohistochemical Detection of Nestin in Pediatric Brain Tumors
Nestin is an intermediate filament protein (IFP) expressed in undifferentiated cells during CNS development and in CNS tumors. Previous studies have arrived at different conclusions in terms of which types of CNS tumors express nestin. In this report we
Urban Lendahl +4 more
core +1 more source
Bmal1 regulates astrocyte extracellular matrix (ECM) gene expression. Bmal1 deletion in astrocytes disrupts normal circadian rhythms in perineuronal nets (PNN) and reduces PNN content in the hippocampus. In parallel with loss of PNNs, deletion of the core circadian clock gene Bmal1 in astrocytes alters behavior and synaptic function in vivo.
Philip C. Smith +6 more
wiley +1 more source
Role of Nestin in Mouse Development
Although nestin has served as a marker of neural stem/progenitor cells for close to twenty years, its function is still poorly understood. During development, this intermediate filament protein is expressed in many different progenitors including those ...
Mohseni, Paria
core
Cytoskeletal Dynamics in Cancer: From Pathogenesis to Treatment
This review systematically addresses the fundamental roles of the cytoskeleton (actin filaments, microtubules, and intermediate filaments) in cancer progression. We focus on how cytoskeletal dynamics regulate tumor proliferation, metastasis, and programmed cell death, while also modulating the immune microenvironment. Understanding these mechanisms may
Jie Chen +9 more
wiley +1 more source
Human Cortical Neural Progenitor Cells
Cell Proliferation, EarlyView.
An‐Xin Wang +29 more
wiley +1 more source
Immunohistochemical analysis of nestin expression in UCB.
The photographs are representative tumor cells that were negative (A) and positive (B) for nestin. Nestin expression was also observed in the cytoplasm of vascular endothelial cells and fibroblasts in tumor stroma in each case (Figure 1A, B).
Sho Minami (558737) +8 more
core +1 more source
【目的】 了解Nestin在小鼠正常和损伤心脏组织中的表达及分布特征,探讨Nestin能否作为心肌干细胞的标志物。【方法】 通过倒置荧光显微镜观察、RT-PCR和实时荧光定量PCR检测,分析Nestin在胚胎期13.5 d、出生后1 d、7 d、1月、3月的Nestin-GFP转基因小鼠心脏组织中的表达情况;建立小鼠心肌梗死模型,观察损伤后心肌组织中Nestin的表达情况;利用免疫荧光染色法检测小鼠心脏组织中Nestin与多种干细胞标记物的共表达关系。【结果】 胚胎13.5 d ...
doaj
Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
Hyperplastic dental follicles (HDFs) represent odontogenic hamartomatous lesions originating from the pericoronal tissues and are often associated with impacted or embedded teeth.
Hiromasa Hasegawa +3 more
doaj +1 more source
ABSTRACT Peripheral nerve injury (PNI) is one of the common life‐altering disabilities resulting in various degrees of impairment in movement and sensation alongside apraxia and long‐lasting pain. The gold standard for restoring the transected nerves is bridging the distal and proximal ends of disrupted autologous nerve using neurosurgical sutures ...
Giovanna Casili +8 more
wiley +1 more source

