Results 121 to 130 of about 41,897 (208)
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Although purinergic P2Y2 receptor can regulate neural stem cell (NSC) proliferation and neurogenesis in mammals, it is downregulated following spinal cord injury (SCI). It was previously unknown whether this receptor regulates these processes in the more‐regenerative zebrafish model, where the contribution of these responses allows near‐complete ...
Isaac J. Sullivan +7 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 33, 4 September 2026.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
The role of the intermediate filament (nanofilament) protein nestin in neural progenitor cell and astrocyte differentiation [PDF]
, 2014 Nestin, a class VI intermediate filament (nanofilament) protein, is commonly used as a marker for neural stem/progenitor cells (NSPCs), but its role in neurogenesis remains elusive. Nestin is also expressed in immature and reactive astrocytes.
Lebkuechner, Isabell
core
Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Role of nestin in tumor cell proliferation.
, 2014 (A) A549 or H460 cells stably expressing shRNA against nestin (shRNA1, shRNA2) were established and nestin knockdown, compared to A549 or H460 cells transfected with a scrambled shRNA sequence (control vector), confirmed with immunofluorescence staining (
Chunhua Su (518938) +12 more
core +1 more source
BMC Molecular and Cell BiologyBackground Dual leucine zipper kinase (DLK) is critical for neurite outgrowth in the developing nervous system and during nerve regeneration, but the underlying mechanisms remain largely unknown.
Guillaume St-Cyr +3 more
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 33, 4 September 2026.This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg +8 more
wiley +1 more source
Intermediate filament nestin expressions in human cord blood monocytes (HCMNCs)
, 2003 OBJECTS: Nestin is an intermediate protein and a well-known specific neural stem cell antigen. Some bone marrow stem cells can generate not only blood cells but also neurons and glial cells under specific culture conditions.
윤도흠, 김긍년
core +1 more source
Advanced Science, Volume 13, Issue 51, 14 September 2026.Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li +13 more
wiley +1 more source
Supplementary Figure S4 from Nestin Mediates Hedgehog Pathway Tumorigenesis
, 2016 Nestin knockdown in MB cells by Nestin ...
Renata E. Gordon (6989132) +12 more
core +1 more source