Results 141 to 150 of about 41,897 (208)

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen, Jiayi Wang, Jimin Yu, Yiran Zhou, Lihai Liu, Jing Liu, Liang Wang   +6 more
wiley   +1 more source

Transcriptional Profiling of Growth Hormone–Secreting Pituitary Adenoma Stem‐Like Cells: Unveiling the Significant Role of CXCR4 in Tumorigenesis and Clinical Applications

MedComm, Volume 7, Issue 9, September 2026.
Growth hormone–secreting pituitary adenomas harbor hPASCs (human pituitary adenoma stem‐like cells). Genetic profiling of hPASCs identified CXCR4 as a significant gene orchestrating a regulatory network in the self‐renewal and differentiation of hPASCs, as well as the modulation of tumor cells and the microenvironment.
LinHao Yuan, Hao Yang, BaoWang Li, Huimin Sui, Peiliang Li, Xu Wang, Jiang Li, Guijun Jia, Zhaohui Zhu, Deling Li, Wang Jia, Peng Kang   +11 more
wiley   +1 more source

Stress‐Adaptive Biomaterials With Tunable Yielding Architectures Regulate Organoid Morphogenesis

Small, Volume 22, Issue 50, 7 September 2026.
Granular hydrogels are developed to tune the yield stress levels at which 3D tissue culture matrices undergo plastic deformation. We use these materials to regulate growth‐induced stresses, with demonstrable effects on cancer spheroid invasion and brain organoid morphogenesis.
James P. W. Reeves, Sabra Rostami, Mostafa Rammal, Andrei Bocan, Paula Lépine, Matthew J. Harrington, Thomas M. Durcan, Christopher Moraes   +7 more
wiley   +1 more source

Patient‐Derived iPSC‐MSC Modelling Reveals Reversible GSK3‐Mediated Suppression of Mesenchymal Lineage Differentiation in Legg‐Calvé‐Perthes Disease

Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Legg‐Calvé‐Perthes disease (LCPD) is an idiopathic paediatric osteonecrosis characterized by avascular injury to the femoral head, resulting in structural collapse and early osteoarthritis. Although mesenchymal stem cell (MSC) dysfunction has been implicated, the underlying mechanisms remain unclear due to the absence of human disease models ...
Binna Seol, Hyung Jin Lim, Cho Lok Song, Jungwoon Lee, Yee Sook Cho   +4 more
wiley   +1 more source

Evidence for a Neural Stem Cell Niche in the Postnatal Rat Vestibular Ganglion: An In Vitro Study. [PDF]

Stem Cells Int
Sommerer S, Rak K, Spahn B, Hackenberg S, Voelker J, Engert J.   +5 more
europepmc   +1 more source

Protocol for functional characterization of adult hippocampal neural precursor cells under demyelinating injury conditions in mice. [PDF]

STAR Protoc
Nemati S, Karimi-Abdolrezaee S.
europepmc   +1 more source

Nestin expression in normal adrenal gland and adrenocortical tumors

, 2005
Human adrenocortical cells have been shown to express cytokeratins and vimentin. Nestin is an intermediate filament protein that is mainly expressed in the developing nervous system and that has been recently reported in rat adrenal gland as well.
BARTOLOMMEI, S., FONZI, Luciano, OCCHINI, Rossella, REGOLI, Marì, TOTI, Paolo, NESI, G., BERTELLI, Eugenio   +6 more
core  

Engineered Nestin⁺ TSPC-Derived Exosomes Promote Tendon Repair Via Metabolic Reprogramming. [PDF]

J Extracell Vesicles
Cheng L, Guo J, Zhang J, Zheng Q, Zhang Z, Chen J, Zhang J, Chen X, Yin Z.   +8 more
europepmc   +1 more source

Nestin as a Vascular Marker of Angiogenesis in Non-Melanoma Skin Cancer. [PDF]

Cancers (Basel)
Nowogrodzka K, Tota M, Piotrowska A, Bieniek A, Dzięgiel P, Jankowska-Konsur A.   +5 more
europepmc   +1 more source