Results 31 to 40 of about 166,926 (313)
Few regulatory metabolites coordinate expression of central metabolic genes in Escherichia coli
Molecular Systems Biology, 2017 Transcription networks consist of hundreds of transcription factors with thousands of often overlapping target genes. While we can reliably measure gene expression changes, we still understand relatively little why expression changes the way it does. How
Karl Kochanowski +5 more
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Frontiers in Genetics, 2017 Perturbation of biological networks is often observed during exposure to xenobiotics, and the identification of disturbed processes, their dynamic traits, and dose–response relationships are some of the current challenges for elucidating the mechanisms ...
Terezinha M. Souza +2 more
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Ensemble Inference and Inferability of Gene Regulatory Networks
PLoS ONE, 2014 The inference of gene regulatory network (GRN) from gene expression data is an unsolved problem of great importance. This inference has been stated, though not proven, to be underdetermined implying that there could be many equivalent (indistinguishable) solutions. Motivated by this fundamental limitation, we have developed new framework and algorithm,
Ud-Dean Minhaz, Gunawan Rudiyanto
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A systems‐level approach to mapping the telomere length maintenance gene circuitry
Molecular Systems Biology, 2008 The ends of eukaryotic chromosomes are protected by telomeres, nucleoprotein structures that are essential for chromosomal stability and integrity. Understanding how telomere length is controlled has significant medical implications, especially in the ...
Rafi Shachar +4 more
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Frontiers in Plant Science, 2019 Photoperiodic flowering, a plant response to seasonal photoperiod changes in the control of reproductive transition, is an important agronomic trait that has been a central target of crop domestication and modern breeding programs.
Faqiang Wu +6 more
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Frontiers in Genetics, 2023 Gene regulatory networks are graph models representing cellular transcription events. Networks are far from complete due to time and resource consumption for experimental validation and curation of the interactions.
Juan M. Escorcia-Rodríguez +9 more
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Network inference and biological dynamics [PDF]
The Annals of Applied Statistics, 2012 Published in at http://dx.doi.org/10.1214/11-AOAS532 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Oates, Chris. J., Mukherjee, Sach
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Blind Wireless Network Topology Inference
IEEE Transactions on Communications, 2021 This work proposes a framework to discover the topology of a non-collaborative packet-based wireless network using radio-frequency (RF) sensors. The methodology developed is blind, allowing topology sensing of a network whose key features (i.e., number of nodes, physical layer signals, and medium access control (MAC) and routing protocols) are unknown.
Testi, Enrico, Giorgetti, Andrea
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Frontiers in Microbiology, 2019 An intriguing aspect in microbial communities is that pairwise interactions can be influenced by neighboring species. This creates context dependencies for microbial interactions that are based on the functional composition of the community.
Hyun-Seob Song +10 more
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Network inference using informative priors [PDF]
Proceedings of the National Academy of Sciences, 2008 Recent years have seen much interest in the study of systems characterized by multiple interacting components. A class of statistical models called graphical models, in which graphs are used to represent probabilistic relationships between variables, provides a framework for formal inference regarding such systems.
Sach, Mukherjee, Terence P, Speed
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