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Network pharmacology: a bright guiding light on the way to explore the personalized precise medication of traditional Chinese medicine

Chinese Medicine, 2023
Network pharmacology can ascertain the therapeutic mechanism of drugs for treating diseases at the level of biological targets and pathways. The effective mechanism study of traditional Chinese medicine (TCM) characterized by multi-component, multi ...
Ling Li, Lele Yang, Liuqing Yang, Chunrong He, Yuxin He, Liping Chen, Qin Dong, Huaiying Zhang, Shiyun Chen, Peng Li   +9 more
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Progress and Prospects of Research Ideas and Methods in the Network Pharmacology of Traditional Chinese Medicine

Journal of Pharmacy & Pharmaceutical Sciences, 2022
In recent years, the emerging network pharmacology has been extensively applied to the field of traditional Chinese medicine and has made great contributions to the modernization of TCM.
Zhongzhu Yuan, Yingying Pan , Tian Leng, Yu Chu, Haojie Zhang, Jingru Ma, Xiaoju Ma   +6 more
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Network Pharmacology Approach for Medicinal Plants: Review and Assessment

Pharmaceuticals, 2022
Natural products have played a critical role in medicine due to their ability to bind and modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive scaffolds for the treatment of multiple disorders.
Fatima Noor, Muhammad Tahir ul Qamar, Usman Ali Ashfaq, Aqel Albutti, Ameen S. S. Alwashmi, Mohammad Abdullah Aljasir   +5 more
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Analyzing the research landscape: Mapping frontiers and hot spots in anti-cancer research using bibliometric analysis and research network pharmacology

Frontiers in Pharmacology, 2023
Introduction: Network pharmacology has emerged as a forefront and hotspot in anti-cancer. Traditional anti-cancer drugs are limited by the paradigm of “one cancer, one target, one drug,” making it difficult to address the challenges of recurrence and ...
Qi Han, Qi Han, Zhongxun Li, Zhongxun Li, Yang Fu, Hongliang Liu, Hongliang Liu, Hongliang Liu, Hongliang Liu, Huina Guo, Huina Guo, Xiaoya Guan, Xiaoya Guan, Min Niu, Min Niu, Chunming Zhang, Chunming Zhang, Chunming Zhang   +17 more
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Network Pharmacology Databases for Traditional Chinese Medicine: Review and Assessment

Frontiers in Pharmacology, 2019
The research field of systems biology has greatly advanced and, as a result, the concept of network pharmacology has been developed. This advancement, in turn, has shifted the paradigm from a “one-target, one-drug” mode to a “network-target, multiple ...
Runzhi Zhang, Xue Zhu, Hong Bai, Kang Ning   +3 more
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Application of network pharmacology in the study of mechanism of Chinese medicine in the treatment of ulcerative colitis: A review

Frontiers in Bioinformatics, 2022
Network pharmacology is a research method based on a multidisciplinary holistic analysis of biological systems, which coincides with the idea of the holistic view of traditional Chinese medicine.
Shihao Zheng, Tianyu Xue, Bin Wang, Haolin Guo, Qiquan Liu, Qiquan Liu   +5 more
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TCM‐Suite: A comprehensive and holistic platform for Traditional Chinese Medicine component identification and network pharmacology analysis

iMeta, 2022
DNA‐based biological ingredient identification and downstream pharmacology network analysis are commonly used in research for Traditional Chinese Medicine preparations (TCM formulas).
Pengshuo Yang, Jidong Lang, Hongjun Li, Jinxiang Lu, Hanyang Lin, Geng Tian, Hong Bai, Jialiang Yang, Kang Ning   +8 more
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Application of network pharmacology in the study of the mechanism of action of traditional chinese medicine in the treatment of COVID-19

Frontiers in Pharmacology, 2022
Network pharmacology was rapidly developed based on multidisciplinary holistic analysis of biological systems, which has become a popular tool in traditional Chinese medicine (TCM) research in recent years.
Shihao Zheng, Tianyu Xue, Bin Wang, Haolin Guo, Qiquan Liu, Qiquan Liu   +5 more
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Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model [PDF]

npj Science of Food
Research indicated that berberine (BBR) plays a protective role in modulating Alzheimer’s disease (AD). This study aimed to explore the target genes of BBR associated with AD therapy using a network pharmacology study.
Yaoyi Zhang, Shuai Lv, Pinyuan Huang, Lingmin Xiao, Nan Lin, En Huang   +5 more
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Research trends and hotspots of neurodegenerative diseases employing network pharmacology: A bibliometric analysis

Frontiers in Pharmacology, 2023
Background: Employing network pharmacology in neurodegenerative diseases (NDs) has been extensively studied recently. However, no comprehensive study has conducted on this subject employing bibliometrics so far.
Jie Zhu, Qingchun Liang, Siyi He, Chen Wang, Xiafei Lin, Duozhi Wu, Guanwen Lin, Zhihua Wang   +7 more
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