Results 1 to 10 of about 446,122 (242)

Tinnitus: Network pathophysiology-network pharmacology [PDF]

Frontiers in Systems Neuroscience, 2012
Tinnitus, the phantom perception of sound, is a prevalent disorder. One in 10 adults has clinically significant subjective tinnitus, and for 1 in 100, tinnitus severely affects their quality of life. Despite the significant unmet clinical need for a safe
Ana Belen eElgoyhen, Berthold eLangguth, Sven eVanneste, Dirk eDe Ridder   +3 more
doaj   +5 more sources

Network pharmacology: a crucial approach in traditional Chinese medicine research [PDF]

Chinese Medicine
Network pharmacology plays a pivotal role in systems biology, bridging the gap between traditional Chinese medicine (TCM) theory and contemporary pharmacological research.
Yiyan Zhai, Liu Liu, Fanqin Zhang, Xiaodong Chen, Haojia Wang, Jiying Zhou, Keyan Chai, Jiangying Liu, Huiling Lei, Peiying Lu, Meiling Guo, Jincheng Guo, Jiarui Wu   +12 more
doaj   +2 more sources

Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model [PDF]

npj Science of Food
Research indicated that berberine (BBR) plays a protective role in modulating Alzheimer’s disease (AD). This study aimed to explore the target genes of BBR associated with AD therapy using a network pharmacology study.
Yaoyi Zhang, Shuai Lv, Pinyuan Huang, Lingmin Xiao, Nan Lin, En Huang   +5 more
doaj   +2 more sources

Research trends and hotspots of neurodegenerative diseases employing network pharmacology: A bibliometric analysis

Frontiers in Pharmacology, 2023
Background: Employing network pharmacology in neurodegenerative diseases (NDs) has been extensively studied recently. However, no comprehensive study has conducted on this subject employing bibliometrics so far.
Jie Zhu, Qingchun Liang, Siyi He, Chen Wang, Xiafei Lin, Duozhi Wu, Guanwen Lin, Zhihua Wang   +7 more
doaj   +1 more source

Progress and Prospects of Research Ideas and Methods in the Network Pharmacology of Traditional Chinese Medicine

Journal of Pharmacy & Pharmaceutical Sciences, 2022
In recent years, the emerging network pharmacology has been extensively applied to the field of traditional Chinese medicine and has made great contributions to the modernization of TCM.
Zhongzhu Yuan, Yingying Pan , Tian Leng, Yu Chu, Haojie Zhang, Jingru Ma, Xiaoju Ma   +6 more
doaj   +1 more source

Network pharmacology: a bright guiding light on the way to explore the personalized precise medication of traditional Chinese medicine

Chinese Medicine, 2023
Network pharmacology can ascertain the therapeutic mechanism of drugs for treating diseases at the level of biological targets and pathways. The effective mechanism study of traditional Chinese medicine (TCM) characterized by multi-component, multi ...
Ling Li, Lele Yang, Liuqing Yang, Chunrong He, Yuxin He, Liping Chen, Qin Dong, Huaiying Zhang, Shiyun Chen, Peng Li   +9 more
doaj   +1 more source

Mechanism of Action of Hawthorn Leaves against Hyperlipidemia Based on Network Pharmacology and Preliminary Validation Study

Shipin gongye ke-ji, 2022
Objective: Network pharmacology was used to predict potential compounds, targets and pathways of action in hawthorn leaves for the treatment of hyperlipidaemia, and the network pharmacology predictions were validated in conjunction with target enzyme and
Xuegui LIU, Zhiming LI, Changfeng LIU, Jingyao ZHOU, Yaoyao WANG, Pinyi GAO, Danqi LI   +6 more
doaj   +1 more source

Application of network pharmacology in the study of mechanism of Chinese medicine in the treatment of ulcerative colitis: A review

Frontiers in Bioinformatics, 2022
Network pharmacology is a research method based on a multidisciplinary holistic analysis of biological systems, which coincides with the idea of the holistic view of traditional Chinese medicine.
Shihao Zheng, Tianyu Xue, Bin Wang, Haolin Guo, Qiquan Liu, Qiquan Liu   +5 more
doaj   +1 more source

Effect of Fushengong Decoction on PTEN/PI3K/AKT/NF-κB Pathway in Rats With Chronic Renal Failure via Dual-Dimension Network Pharmacology Strategy

Frontiers in Pharmacology, 2022
Overview: The treatment of chronic renal failure (CRF) with traditional Chinese medicine has attracted much attention, but its mechanism is not clear. Network pharmacology is an effective strategy for exploring the interaction mechanisms between Chinese ...
Hongyu Luo, Munan Wang, Ke Xu, Qiyao Peng, Bo Zou, Shi Yin, Chao Yu, Lingyan Ren, Ping Li, Li Tang, Yongbo Peng, Xuekuan Huang   +11 more
doaj   +1 more source

Network pharmacology of JAK inhibitors [PDF]

Proceedings of the National Academy of Sciences, 2016
SignificanceJAK kinase inhibitors (JAKis) have advanced options for treatment of autoimmune diseases. Because JAKs are signaling hubs for several cytokine receptors, JAKis’ overall impact on the immune system and how they actually improve diseases like rheumatoid arthritis remain poorly understood.
Christophe Benoist, Natasha Asinovski, Sara Mostafavi, Diane Mathis, Devapregasan Moodley, Adriana Ortiz-Lopez, James D. Clark, Peter T. Symanowicz, Jean-Baptiste Telliez, Hideyuki Yoshida, Martin Hegen   +10 more
openaire   +2 more sources