Results 31 to 40 of about 4,728,401 (305)

Pharmacological mechanism of JiaWeiSiWu granule in the treatment of hypertension based on network pharmacology [PDF]

Annals of Palliative Medicine, 2021
JiaWeiSiWu granule (JWSWG) has been applied clinically for more than a decade, and the preliminary results show that blood pressure can be reduced while protecting the target organ at the same time. The purpose of this research is to study the pharmacological mechanism of JWSWG in treating hypertension using network pharmacology.The chief active ...
Lun, Chen, Tong, Zhu, Jia, Qi, Yufeng, Zhang, Zigang, Zhang, Haitao, Liu   +5 more
openaire   +2 more sources

Simultaneous clustering analysis with molecular docking in network pharmacology for type 2 antidiabetic compounds [PDF]

, 2017
The database of drug compounds and human proteins plays a very important role in identifying the protein target and the compound in drug discovery. Recently, a network pharmacology approach was established by updating the research paradigm from the ...
Afendi, Farit Mochamad, Farit Mochamad Afendi, I Made Sumertajaya, Sumertajaya, I Made, Nur Azizah Komara Rifai, Rifai, Nur Azizah Komara   +5 more
core   +1 more source

Application progress of network pharmacology in the related research of diet therapy nursing

Huli yanjiu, 2022
Network pharmacology is a new subject based on the theory of systems biology，and has developed rapidly in recent years，especially in clinical and pharmacy applications.In this paper，on the basis of reading and sorting out previous studies related to ...
HAN Shifan, ZHU Ruifang, CHEN Yulu, CAO Yan, FENG Yaoqing, ZHANG Qian, CHEN Junxiang, ZHANG Jun   +7 more
doaj  

A visual analysis of network pharmacology research trends

World Journal of Traditional Chinese Medicine, 2018
Objective: To understand the current situation of network pharmacology, and to analyze external and internal characteristics of literature, is of great significance for the development of network pharmacology in the future and its application in the ...
Shen Xiao, Fang-Qing Zhao, Qi-Ming Wang, Yun-Ru Dong, Shein-Chung Chow, Meng-Zhen Fan, Bo Xing, Fei Zhai, Rong-Wu Xiang   +8 more
doaj   +1 more source

Network Pharmacology‐Based Analysis of the Pharmacological Mechanisms of Aloperine on Cardiovascular Disease [PDF]

Evidence-Based Complementary and Alternative Medicine, 2020
Background. Aloperine is an active component of Sophora alopecuroides Linn, which has been extensively applied for the treatment of cardiovascular disease (CVD). However, our current understanding of the molecular mechanisms supporting the effects of aloperine on CVD remains unclear. Methods.
Bingwu Huang, Juncheng Xiong, Xuyong Zhao, Yihan Zheng, Ning Zhu   +4 more
openaire   +2 more sources

Boolean network modeling in systems pharmacology [PDF]

Journal of Pharmacokinetics and Pharmacodynamics, 2018
Quantitative systems pharmacology (QSP) is an emerging discipline that aims to discover how drugs modulate the dynamics of biological components in molecular and cellular networks and the impact of those perturbations on human pathophysiology. The integration of systems-based experimental and computational approaches is required to facilitate the ...
Peter Bloomingdale, Van Anh Nguyen, Jin Niu, Donald E. Mager   +3 more
openaire   +2 more sources

Guest editorial: Pharmacology of female sexual behavior [PDF]

, 2014
Female sexual behavior has been studied over the last decades from many perspectives, e.g. biological function, endocrinology and brain mechanisms, but is has never developed into a big research area. However, in the last decade an increasing interest in
Sub BasicPharmacology&Psychopharmacology, Waldinger, Marcel, Olivier, Berend, Pharmacology, Sub General Pharmacology   +4 more
core   +1 more source

Integrating Metabolomics and Network Pharmacology to Decipher the Hepatoprotective Effect Mechanisms of Magnesium Isoglycyrrhizinate Injection

, 2023
This study aimed to explore the liver protective effects of a fourth-generation glycyrrhizic acid product (magnesium isoglycyrrhizinate injection, MII) in the treatment of mice with drug-induced liver injury—specifically, to determine its effects ...
Shigang Shen, Yihua Zhang, Zhixin Jia, Dong Zhao, Ming Su, Xueli Liu, Hui Li, Qiang Wang   +7 more
core   +1 more source

Multivariate Statistical Analysis of Metabolites in Anisodus tanguticus (Maxim.) Pascher to Determine Geographical Origins and Network Pharmacology

Frontiers in Plant Science, 2022
Anisodus tanguticus (Maxim.) Pascher, has been used for the treatment of septic shock, analgesia, motion sickness, and anesthesia in traditional Tibetan medicine for 2,000 years.
Chen Chen, Chen Chen, Bo Wang, Bo Wang, Jingjing Li, Feng Xiong, Guoying Zhou   +6 more
doaj   +1 more source

Network Pharmacology-Based Strategy for the Investigation of the Anti-Obesity Effects of an Ethanolic Extract of Zanthoxylum bungeanum Maxim

Frontiers in Pharmacology, 2020
Network pharmacology is considered as the next paradigm in drug discovery. In an era when obesity has become global epidemic, network pharmacology becomes an ideal tool to discover novel herbal-based therapeutics with effective anti-obesity effects ...
Ying Wang, Song Hong Yang, Keying Zhong, Ting Jiang, Mi Zhang, Hiu Yee Kwan, Tao Su   +6 more
doaj   +1 more source