Results 31 to 40 of about 17,342 (262)
Frontiers in Pharmacology, 2022 Network pharmacology was rapidly developed based on multidisciplinary holistic analysis of biological systems, which has become a popular tool in traditional Chinese medicine (TCM) research in recent years.
Shihao Zheng +5 more
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Bioscience Reports, 2022 Abstract Objective: Andrographis paniculata (Burm.f.) Nees is a medicinal plant that has been traditionally used as an anti-inflammatory and antibacterial remedy for several conditions. Andrographolide (AG), the active constituent of A. paniculata (Burm.f.) Nees, has anti-lipidic and anti-inflammatory properties as well as cardiovascular
Shuai Shi +8 more
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From single drug targets to synergistic network pharmacology in ischemic stroke [PDF]
, 2019 Drug discovery faces an efficacy crisis to which ineffective mainly single-target and symptom-based rather than mechanistic approaches have contributed. We here explore a mechanism-based disease definition for network pharmacology.
Guney, Emre +12 more
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Application progress of network pharmacology in the related research of diet therapy nursing
Huli yanjiu, 2022 Network pharmacology is a new subject based on the theory of systems biology，and has developed rapidly in recent years，especially in clinical and pharmacy applications.In this paper，on the basis of reading and sorting out previous studies related to ...
HAN Shifan +7 more
doaj
, 2023 This study aimed to explore the liver protective effects of a fourth-generation glycyrrhizic acid product (magnesium isoglycyrrhizinate injection, MII) in the treatment of mice with drug-induced liver injury—specifically, to determine its effects ...
Shigang Shen +7 more
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Network Pharmacology‐Based Analysis of the Pharmacological Mechanisms of Aloperine on Cardiovascular Disease [PDF]
Evidence-Based Complementary and Alternative Medicine, 2020 Background. Aloperine is an active component of Sophora alopecuroides Linn, which has been extensively applied for the treatment of cardiovascular disease (CVD). However, our current understanding of the molecular mechanisms supporting the effects of aloperine on CVD remains unclear. Methods.
Bingwu Huang +4 more
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Boolean network modeling in systems pharmacology [PDF]
Journal of Pharmacokinetics and Pharmacodynamics, 2018 Quantitative systems pharmacology (QSP) is an emerging discipline that aims to discover how drugs modulate the dynamics of biological components in molecular and cellular networks and the impact of those perturbations on human pathophysiology. The integration of systems-based experimental and computational approaches is required to facilitate the ...
Peter Bloomingdale +3 more
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Systematically Deciphering the Pharmacological Mechanism of Fructus Aurantii via Network Pharmacology [PDF]
Evidence-Based Complementary and Alternative Medicine, 2021 Fructus Aurantii (FA) is a traditional herbal medicine that has been widely used for thousands of years in China and possesses a variety of pharmacological effects. However, the active ingredients in FA and the potential mechanisms of its therapeutic effects have not been fully explored.
Qionglong Jin +5 more
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Frontiers in Plant Science, 2022 Anisodus tanguticus (Maxim.) Pascher, has been used for the treatment of septic shock, analgesia, motion sickness, and anesthesia in traditional Tibetan medicine for 2,000 years.
Chen Chen +6 more
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The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology
Biomolecules, 2019 Natural products, including traditional herbal medicine (THM), are known to exert their therapeutic effects by acting on multiple targets, so researchers have employed network pharmacology methods to decipher the potential mechanisms of THM.
Won-Yung Lee +3 more
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