Results 31 to 40 of about 339,960 (301)

A visual analysis of network pharmacology research trends

open access: yesWorld Journal of Traditional Chinese Medicine, 2018
Objective: To understand the current situation of network pharmacology, and to analyze external and internal characteristics of literature, is of great significance for the development of network pharmacology in the future and its application in the ...
Shen Xiao   +8 more
doaj   +1 more source

Cost-Utility Analysis of Venous Thromboembolism Prophylaxis Strategies for People Undergoing Elective Total Hip and Total Knee Replacement Surgeries in the English National Health Service [PDF]

open access: yes, 2018
Background: Major orthopedic surgery, such as elective total hip replacement (eTHR) and elective total knee replacement (eTKR), are associated with a higher risk of venous thromboembolism (VTE) than other surgical procedures.
Anderson   +53 more
core   +4 more sources

Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer's Precision Medicine and Pharmacology. [PDF]

open access: yes, 2019
Systems biology studies have demonstrated that different (epi)genetic and pathophysiological alterations may be mapped onto a single tumor's clinical phenotype thereby revealing commonalities shared by cancers with divergent phenotypes.
Goetzl, Edward J   +4 more
core   +2 more sources

Clinical Pharmacology & Therapeutics: Past, Present, and Future. [PDF]

open access: yes, 2017
Clinical Pharmacology & Therapeutics (CPT), the definitive and timely source for advances in human therapeutics, transcends the drug discovery, development, regulation, and utilization continuum to catalyze, evolve, and disseminate discipline ...
Terzic, Andre, Waldman, Scott A.
core   +2 more sources

The Scientific Competitiveness of Nations [PDF]

open access: yes, 2014
We use citation data of scientific articles produced by individual nations in different scientific domains to determine the structure and efficiency of national research systems.
Cimini, Giulio   +2 more
core   +3 more sources

Boolean network modeling in systems pharmacology [PDF]

open access: yesJournal of Pharmacokinetics and Pharmacodynamics, 2018
Quantitative systems pharmacology (QSP) is an emerging discipline that aims to discover how drugs modulate the dynamics of biological components in molecular and cellular networks and the impact of those perturbations on human pathophysiology. The integration of systems-based experimental and computational approaches is required to facilitate the ...
Peter Bloomingdale   +3 more
openaire   +2 more sources

Multivariate Statistical Analysis of Metabolites in Anisodus tanguticus (Maxim.) Pascher to Determine Geographical Origins and Network Pharmacology

open access: yesFrontiers in Plant Science, 2022
Anisodus tanguticus (Maxim.) Pascher, has been used for the treatment of septic shock, analgesia, motion sickness, and anesthesia in traditional Tibetan medicine for 2,000 years.
Chen Chen   +6 more
doaj   +1 more source

Network Pharmacology and Pharmacological Mechanism of CV-3 in Atrial Fibrillation

open access: yesEvidence-Based Complementary and Alternative Medicine, 2022
The high fatality and disability rate of atrial fibrillation (AF) strongly promote the development of pathogenesis and treatment of AF that is of great value. The present research attempted to clarify potential mechanisms of Mujiangzi oil (CV-3) in treating AF by constructing an AF cardiomyocytes model and using a network pharmacology approach.
Zundong Wang   +5 more
openaire   +2 more sources

Network Pharmacology-Based Strategy for the Investigation of the Anti-Obesity Effects of an Ethanolic Extract of Zanthoxylum bungeanum Maxim

open access: yesFrontiers in Pharmacology, 2020
Network pharmacology is considered as the next paradigm in drug discovery. In an era when obesity has become global epidemic, network pharmacology becomes an ideal tool to discover novel herbal-based therapeutics with effective anti-obesity effects ...
Ying Wang   +6 more
doaj   +1 more source

Andrographolide in atherosclerosis: integrating network pharmacology and in vitro pharmacological evaluation

open access: yesBioscience Reports, 2022
Abstract Objective: Andrographis paniculata (Burm.f.) Nees is a medicinal plant that has been traditionally used as an anti-inflammatory and antibacterial remedy for several conditions. Andrographolide (AG), the active constituent of A. paniculata (Burm.f.) Nees, has anti-lipidic and anti-inflammatory properties as well as cardiovascular
Shuai Shi   +8 more
openaire   +2 more sources

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