Results 101 to 110 of about 1,943 (161)

Investigating the Utility of Leukocyte Sialic Acid Measurements in Lysosomal Free Sialic Acid Storage Disorder

JIMD Reports
Lysosomal free sialic acid storage disorder (FSASD) is a rare, multisystem neurodegenerative disease caused by biallelic pathogenic variants in SLC17A5, encoding sialin.
Marya S. Sabir, Laura Pollard, Lynne Wolfe, David R. Adams, Carla Ciccone, Petcharat Leoyklang, Frances M. Platt, Marjan Huizing, William A. Gahl, May Christine V. Malicdan   +9 more
doaj   +1 more source

A New Synthesis of Neu5Ac from d-Glucono-δ-lactone

, 2016
A new route to Neu5Ac methyl ester (23) with a readily available sugar d-glucono-δ-lactone as starting material has been developed. A diastereoselective propargylation of α-acetamino aldehyde and a subsequent KMnO4 oxidation of the terminal alkyne served
Shi Yan (164233), Ke-Gang Liu (2681785), Zhu-Jun Yao (297585), Yu-Lin Wu (2714392)   +3 more
core   +1 more source

Assessment of Sialic Acid Content in Dairy Products from Buffalo’s and Goat’s Milk Compared to Cow’s Milk

Dairy
Sialic acids (SIAs) are bioactive compounds present in glycoproteins and glycolipids, playing key roles in human physiology. N-acetylneuraminic acid (Neu5Ac), the only sialic acid synthesized by humans, contributes to neurodevelopment and immune function,
Simona Rinaldi, Michela Contò, Carlo Boselli, Giuliano Palocci, Angelo Citro, Sebastiana Failla   +5 more
doaj   +1 more source

Synthesis of a novel CMP-Neu5Ac analogue : CMP-[a-Neu5Ac (2-8) -Neu5Ac].

Synthesis of a novel CMP-Neu5Ac analogue : CMP-[a-Neu5Ac (2-8) -Neu5Ac].
identifier:oai:t2r2.star.titech.ac.jp ...
openaire   +1 more source

The reversible condensation reaction between ManNAc and pyruvate giving Neu5Ac catalyzed by NAL.

, 2019
The reversible condensation reaction between ManNAc and pyruvate giving Neu5Ac catalyzed by NAL.
Inger Lin U. Ræder (6824228), Man Kumari Gurung (6824222), Arne O. Smalås (6824225), Bjørn Altermark (3399611), Ronny Helland (143018)   +4 more
core   +1 more source

Development and evaluation of an immunoassay for the quantification of N-acetylneuraminic acid (Neu5Ac) in foods and biosamples

Food Chemistry
N-acetylneuraminic acid is an active ingredient in tonic foods and an important additive in foods and biopharmaceuticals. To address the limitations of existing methods of N-acetylneuraminic acid quantification, we developed an immunoassay based on antibodies induced in hens using artificial antigen, showing high sensitivity and specificity with no ...
Longjiang, Wu, Qinqin, Deng, Murtala Bindawa, Isah, Mei, Dang, Xiaoying, Zhang   +4 more
openaire   +2 more sources

Variability of Sialic Acids in Beef Breeds and Nutritional Implications in Red Meat

Molecules
This study examines the variability of sialic acids, specifically N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc), in beef from seven cattle breeds (Holstein Friesian, Red Pied, Maremmana, Chianina, Charolais, Limousin, and ...
Michela Contò, Maria Miarelli, Sabrina Di Giovanni, Sebastiana Failla   +3 more
doaj   +1 more source

Preferential accumulation of ¹⁴C-Neu5Gc over ¹⁴C-Neu5Ac in the brain.

, 2015
Radioactivities in the brain (A), hippocampus (B), cerebellum (C) and blood (D) at 1, 3 and 24 hr after tail vein injection of 14C-Neu5Gc (n = 5) or 14C-Neu5Ac (n = 5–6) are shown as relative values to the radioactivities of injected-14C-Neu5Gc or 14C ...
Kiyoshi Ikeda (508348), Tadanobu Takahashi (235567), Tadamune Otsubo (508346), Yukino Matsuda (758835), Takashi Suzuki (8491), Akira Minami (474027), Risa Taguchi (508354)   +6 more
core   +1 more source

Anomalous Binding Profile of Phenylboronic Acid with N-Acetylneuraminic Acid (Neu5Ac) in Aqueous Solution with Varying pH

, 2016
Borates are known to interact with carbohydrate moieties expressed on the surface of biological membranes of a variety of cells, viruses, bacteria, and fungi.
Hidenori Otsuka (2502940), Eiichiro Uchimura (2988894), Hiroyuki Koshino (492625), Teruo Okano (111448), Kazunori Kataoka (281782)   +4 more
core   +1 more source

Binding of the L-lectin module to Neu5Ac.

, 2014
A) Superposition of the L-lectin module against P. sativum pea lectin (PDB 2BQP) and R. pseudoacacia bark lectin (PDB 1FNZ). The L-lectin module of SraPBR is colored in cyan, with the carbons of sucrose colored in yellow.
Yi-Hu Yang (573494), Na Li (6550), Cong-Zhao Zhou (32471), Yuxing Chen (381885), Xiao-Hui Bai (2571736), Shi-Jie Zhang (573495), Ting Xue (291379), Zhiyong Zhang (44058), Juan Zhang (48597), Lei Wang (6656), Jing-Ren Zhang (271032), Yide Mei (573498), Yong-Liang Jiang (381883), Yan-Min Ren (573496), Yong-Hui Zhang (573497), Qingguo Gong (520009)   +15 more
core   +1 more source