Results 1 to 10 of about 387,435 (125)

Analysis of segmentation ontology reveals the similarities and differences in connectivity onto L2/3 neurons in mouse V1

open access: yesScientific Reports, 2021
Quantitatively comparing brain-wide connectivity of different types of neuron is of vital importance in understanding the function of the mammalian cortex.
Alexander P. Y. Brown   +5 more
doaj   +1 more source

Transient photocurrents in a subthreshold evidence accumulator accelerate perceptual decisions

open access: yesNature Communications, 2023
Perceptual decisions are complete when a continuously updated score of sensory evidence reaches a threshold. In Drosophila, αβ core Kenyon cells (αβc KCs) of the mushroom bodies integrate odor-evoked synaptic inputs to spike threshold at rates that ...
Timothy L. H. Wong   +2 more
doaj   +1 more source

Selective Regional Loss of Cortical Synapses Lacking Presynaptic Mitochondria in the 5xFAD Mouse Model

open access: yesFrontiers in Neuroanatomy, 2021
Synaptic loss in Alzheimer's disease (AD) is strongly correlated with cognitive impairment. Accumulating evidence indicates that amyloid pathology leads to synaptic degeneration and mitochondrial damage in AD. However, it remains unclear whether synapses
Na-young Seo   +7 more
doaj   +1 more source

A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord

open access: yeseLife, 2020
The Drosophila ventral nerve cord (VNC) receives and processes descending signals from the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory information from the periphery and sends ascending signals to the brain. We
Aaron M Allen   +6 more
doaj   +1 more source

Enhancement and contextual modulation of visuospatial processing by thalamocollicular projections from ventral lateral geniculate nucleus

open access: yesNature Communications, 2023
In the mammalian visual system, the ventral lateral geniculate nucleus (vLGN) of the thalamus receives salient visual input from the retina and sends prominent GABAergic axons to the superior colliculus (SC).
Zhong Li   +9 more
doaj   +1 more source

Emergence of local and global synaptic organization on cortical dendrites

open access: yesNature Communications, 2021
Synaptic inputs on neuronal dendrites exhibit remarkable organization at different spatial scales, which emerges during the early postnatal development.
Jan H. Kirchner, Julijana Gjorgjieva
doaj   +1 more source

Large-scale multielectrode recording and stimulation of neural activity [PDF]

open access: yes, 2007
Large circuits of neurons are employed by the brain to encode and process information. How this encoding and processing is carried out is one of the central questions in neuroscience.
Chichilnisky, E. J.   +10 more
core   +1 more source

The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning. [PDF]

open access: yes, 2017
Neuronal ApoE receptors are linked to learning and memory, but the pathways governing their abundance, and the mechanisms by which they affect the function of neural circuits are incompletely understood.
Achiro, Jennifer M   +9 more
core   +3 more sources

Developmental depression-to-facilitation shift controls excitation-inhibition balance

open access: yesCommunications Biology, 2022
Using computational modelling this study proposes that the commonly observed depression-to-facilitation shift across development controls excitation-inhibition balance in the brain.
David W. Jia   +2 more
doaj   +1 more source

Switched-Current Chaotic Neurons [PDF]

open access: yes, 1994
The Letter presents two nonlinear CMOS current-mode circuits that implement neuron soma equations for chaotic neural networks. They have been fabricated in a double-metal, single-poly 1.6µm CMOS technology.
Delgado Restituto, Manuel   +1 more
core   +1 more source

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