Results 111 to 120 of about 112,561 (244)

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang, Guangmin Zheng, Xiaoyong Hu, Feng Tian, Tuo Li, Zheng Zhang, Kan Gong, Shiwei Chen, Lin Yuan, Yu Qi, Lin Li, Daofu Cheng, Liu Liu, Fuqiang Liu, Yujing Sun, Xiangdong Fang, Ruxing Zhao, Bing Liu, Chao Zhang   +18 more
wiley   +1 more source

Exploring the Latent Information in Spatial Transcriptomics Data via Multi‐View Graph Convolutional Network Based on Implicit Contrastive Learning

Advanced Science, EarlyView.
STMIGCL is an implicit contrastive learning‐based multi‐view graph convolutional network framework designed for downstream tasks such as spatial domain recognition, trajectory inference, and spatially variable gene identification. By combining multi‐view learning with contrastive learning and employing contrastive learning methods that enhance contrast
Sheng Ren, Xingyu Liao, Farong Liu, Jie Li, Xin Gao, Bin Yu   +5 more
wiley   +1 more source

Improving Adult Vision Through Pathway‐Specific Training in Augmented Reality

Advanced Science, EarlyView.
Traditional perceptual training approaches are limited by stimulus specificity, treatment efficacy, and patient compliance. A novel altered reality (AR) method is developed to enhance pathway‐specific functions in human adults while performing everyday activities.
Yige Gao, Yulian Zhou, Qing He, Wen Wen, Peng Zhang   +4 more
wiley   +1 more source

HOXD1 regulates neural crest cells differentiation and polycerate development in sheep. [PDF]

Sci Rep
Zhang C, Zhang S, Xu H, Wang G, Zhang H, Di T, Tian L, Chang M, Gao F, Li M, Yang G.   +10 more
europepmc   +1 more source

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

Advanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu, Yuxiao Feng, Mathilde Lepoitevin, Meng Yu, Christian Serre, Jun Ge, Yuan Huang   +6 more
wiley   +1 more source

Erratum: Placode and neural crest origins of congenital deafness in mouse models of Waardenburg-Shah syndrome. [PDF]

iScience
Tan J, Duron A, Sucov HM, Makita T.
europepmc   +1 more source

Residual Stresses and Micro‐voids Propel Metal Diffusion for Filament‐Based Memristors

Advanced Science, EarlyView.
Introducing non‐reactive nitrogen during silver sputtering enables low‐voltage (<60 mV) switching in memristors via nano‐void formation and residual stresses in the gigapascal range. This promotes sub‐micron filamentation and neuromorphic behaviors, including multi‐peak synaptic responses.
Joel Y.Y. Loh, Jason Yuan, Samuel Moor‐Smith, Adam Glustein, Gloria Vytas, Will Taylor, Andres Lombo, Richard J. Curry, Nazir Pyarali Kherani   +8 more
wiley   +1 more source

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

Advanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi, Pan Duan, Mengmeng Zhu, Rong Zhang, Zihua Zhao, Xin Nie, Hanhou He, Li Hou, Xianhui Wang   +8 more
wiley   +1 more source

Manipulation of Oxygen Tension in Damaged Regions via Hypoxia‐Induced IPN Hydrogel Microspheres for Intervertebral Disc Regeneration

Advanced Science, EarlyView.
A novel interpenetrating network hydrogel microsphere (NSC‐Exos@HIMS) is developed to manipulate oxygen tension in damaged regions and recruit endogenous stem cells. In vitro and in vivo results show that NSC‐Exos@HIMS maintains the hypoxia microenvironment for up to 5 days, which triggers nucleus pulposus cell‐like differentiation and enhanced ECM ...
Xingdie Zhou, Zhendong Lv, Zehao Chen, Yiming Xu, Chao Lin, Li Liu, Hao Chen, Bing Niu, Wenguo Cui, Yuhui Zhang   +9 more
wiley   +1 more source

Disturbance‐Aware On‐Chip Training with Mitigation Schemes for Massively Parallel Computing in Analog Deep Learning Accelerator

Advanced Science, EarlyView.
This study proposes novel operational schemes to solve the write disturbance issues in oxide‐semiconductor and capacitor‐based synaptic devices (6T1C devices). These schemes effectively neutralize disturbances, enabling high‐performance on‐chip training of convolutional neural networks and reducing capacitor size over 100 times.
Jaehyeon Kang, Jongun Won, Narae Han, Sangjun Hong, Jee‐Eun Yang, Sangwook Kim, Sangbum Kim   +6 more
wiley   +1 more source