Results 221 to 230 of about 132,267 (353)

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

Advanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint‐Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick   +7 more
wiley   +1 more source

The domestication of the wolf larynx-testing the neural crest connection. [PDF]

R Soc Open Sci
Hansen J, Grunstra NDS, Fitch WT, Kitchener AC, Gumpenberger M, Lesch R.   +5 more
europepmc   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Loss of SPECC1L in cranial neural crest cells results in increased hedgehog signaling and frontonasal dysplasia. [PDF]

Front Physiol
Tran AJ, Hufft-Martinez BM, Thalman DN, Maili L, McKinney SA, Goering JP, Trainor PA, Saadi I.   +7 more
europepmc   +1 more source

Mouse Dac, a novel nuclear factor with homology toDrosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud [PDF]

, 1999
Xavier Caubit, Rajikala Thangarajah, Thomas Theil, Jutta Wirth, Hans Gerd Nothwang, Ulrich R�ther, Stefan Krauß   +6 more
openalex   +1 more source

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

Advanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani, Elena Mancinelli, Gabriele Tullii, Aleksandr Khudiakov, Cristiano Bortolotti, Shubham Tanwar, Peter J. Schwartz, Luca Sala, Maria Rosa Antognazza, Mario Caironi, Adrica Kyndiah   +10 more
wiley   +1 more source

Neural crest cell biology shapes lizard skull evolution across evolutionary time scales. [PDF]

Evol Lett
Horta-Lacueva Q, Uller T, Flecks M, Gabelaia M, Hipsley CA, Kirchner M, Müller J, Feiner N.   +7 more
europepmc   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Tracing the enteric neural crest cell pathway from origin to colonization: insights into Hirschsprung's disease. [PDF]

Mol Biol Rep
Lin H, You J, Hao L, Zheng Z, Zhou J, Xiao J, Feng J, Chen F.   +7 more
europepmc   +1 more source

Decision letter: SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance

, 2020
Grant A. McArthur, Patrícia A. Possik, Andrew G. Cox   +2 more
openalex   +1 more source