Results 101 to 110 of about 395,346 (230)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Harmony in the brain: A narrative review on the shared neural substrates of emotion regulation and creativity

Brain Organoid and Systems Neuroscience Journal
The contribution of creativity in overall well-being through regulating emotions has sparkled research interest in employing artistic interventions recently for the improvement of mental health.
A.I. Ladas, T. Gravalas, C. Katsoridou, C.A. Frantzidis   +3 more
doaj   +1 more source

Bypassing stroke-damaged neural pathways via a neural interface induces targeted cortical adaptation

Nature Communications, 2019
Monkeys were trained to use an artificial cortico-muscular connection (ACMC) to regain control over a paralyzed hand following subcortical stroke. Control over the paralyzed hand was accompanied by the appearance of localized high-gamma modulation in the 
Kenji Kato, Masahiro Sawada, Yukio Nishimura   +2 more
doaj   +1 more source

Neural pathways that control the glucose counterregulatory response

Frontiers in Neuroscience, 2014
Glucose is an essential metabolic substrate for all bodily tissues. The brain depends particularly on a constant supply of glucose to satisfy its energy demands.
Tony eVerberne, Azadeh eSabetghadam, Willian eKorim   +2 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Parallel Excitatory and Inhibitory Neural Circuit Pathways Underlie Reward-Based Phasic Neural Responses

Complexity, 2018
Phasic activity of dopaminergic (DA) neurons in the ventral tegmental area or substantia nigra compacta (VTA/SNc) has been suggested to encode reward-prediction error signal for reinforcement learning. Recent studies have shown that the lateral habenula (
Huanyuan Zhou, KongFatt Wong-Lin, Da-Hui Wang   +2 more
doaj   +1 more source

Cortical Models for Movement Control [PDF]

, 2000
Defense Advanced Research Projects Agency and Office of Naval Research (N0014-95-l-0409)
Bullock, Daniel
core   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Central Neural Pathways Controlling Skeletal Muscle Shivering

Revista Cubana de Investigaciones Biomédicas, 2020
Introduction: Skeletal muscle shivering is the most important source of thermogenesis in the human cold-defensive maintenance of core body temperature (Tcore) and the elevated Tcore during fever. The thermoregulatory reflex pathway through which skin and
Shaun F. Morrison, Ellen Paula Santos da Conceição   +1 more
doaj  

Neural pathways mediating cross education of motor function

Frontiers in Human Neuroscience, 2013
Cross education is the process whereby training of one limb gives rise to enhancements in the performance of the opposite, untrained limb. Despite interest in this phenomenon having been sustained for more than a century, a comprehensive explanation of ...
Kathy L. Ruddy, Kathy L. Ruddy, Richard G. Carson, Richard G. Carson   +3 more
doaj   +1 more source