Results 121 to 130 of about 4,703,918 (382)

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

A vital dye analysis of the timing and pathways of avian trunk neural crest cell migration [PDF]

open access: yes, 1989
To permit a more detailed analysis of neural crest cell migratory pathways in the chick embryo, neural crest cells were labelled with a nondeleterious membrane intercalating vital dye, DiI.
Bronner-Fraser, Marianne E.   +2 more
core  

Descending pathways from hypothalamus to dorsal motor vagus and ambiguus nuclei in the rat [PDF]

open access: yes, 1984
The anatomical pathways between the hypothalamus and cell groups of the lower medulla that are involved in the neural control of endocrine pancreas activity were investigated.
Bellinger   +44 more
core   +3 more sources

Neural pathways of embarrassment and their modulation by social anxiety [PDF]

open access: yesNeuroImage, 2015
While being in the center of attention and exposed to other's evaluations humans are prone to experience embarrassment. To characterize the neural underpinnings of such aversive moments, we induced genuine experiences of embarrassment during person-group interactions in a functional neuroimaging study.
Andreas Jansen   +10 more
openaire   +6 more sources

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

Understanding the Feedforward Artificial Neural Network Model From the Perspective of Network Flow [PDF]

open access: yesarXiv, 2017
In recent years, deep learning based on artificial neural network (ANN) has achieved great success in pattern recognition. However, there is no clear understanding of such neural computational models. In this paper, we try to unravel "black-box" structure of Ann model from network flow.
arxiv  

Sonic hedgehog medulloblastoma cancer stem cells mirnome and transcriptome highlight novel functional networks [PDF]

open access: yes, 2018
Molecular classification has improved the knowledge of medulloblastoma (MB), the most common malignant brain tumour in children, however current treatments cause severe side effects in patients.
Abballe, L.   +10 more
core   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Building the Border: Development of the Chordate Neural Plate Border Region and Its Derivatives

open access: yesFrontiers in Physiology, 2020
The paired cranial sensory organs and peripheral nervous system of vertebrates arise from a thin strip of cells immediately adjacent to the developing neural plate.
Ankita Thawani   +2 more
doaj   +1 more source

Rhombomere rotation reveals that multiple mechanisms contribute to the segmental pattern of hindbrain neural crest migration [PDF]

open access: yes, 1994
Hindbrain neural crest cells adjacent to rhombomeres 2 (r2), r4 and r6 migrate in a segmental pattern, toward the first, second and third branchial arches, respectively.
Bronner-Fraser, Marianne   +2 more
core  

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