Results 31 to 40 of about 29,945 (263)

On Model Explanations with Transferable Neural Pathways

CoRR, 2023
Neural pathways as model explanations consist of a sparse set of neurons that provide the same level of prediction performance as the whole model. Existing methods primarily focus on accuracy and sparsity but the generated pathways may offer limited interpretability thus fall short in explaining the model behavior.
Xinmiao Lin, Wentao Bao, Qi Yu 0001, Yu Kong 0001   +3 more
openaire   +2 more sources

Leptin signaling and leptin resistance

Medical Review, 2022
With the prevalence of obesity and associated comorbidities, studies aimed at revealing mechanisms that regulate energy homeostasis have gained increasing interest. In 1994, the cloning of leptin was a milestone in metabolic research. As an adipocytokine,
Liu Jiarui, Lai Futing, Hou Yujia, Zheng Ruimao   +3 more
doaj   +1 more source

Strengthening functionally specific neural pathways with transcranial brain stimulation [PDF]

, 2018
Cortico-cortical paired associative stimulation (ccPAS) is a recently established offline dual-coil transcranial magnetic stimulation (TMS) protocol 1, 2, 3 based on the Hebbian principle of associative plasticity and designed to transiently enhance ...
Hibbard, P.B., Hibbard, Paul B., Avenanti, A., Silvanto, Juha, Romei, Vincenzo, Avenanti, Alessio, Romei, V., Hibbard, Paul B, Chiappini, E., Chiappini, Emilio, Silvanto, J.   +10 more
core   +1 more source

Brain-based correlates of depression and traumatic brain injury: a systematic review of structural and functional magnetic resonance imaging studies

Frontiers in Neuroimaging
IntroductionDepression is prevalent after traumatic brain injury (TBI). However, there is a lack of understanding of the brain-based correlates of depression post-TBI.
Vanessa A. Baltazar, Ilya Demchenko, Ilya Demchenko, Vanessa K. Tassone, Vanessa K. Tassone, Rachel L. Sousa-Ho, Tom A. Schweizer, Tom A. Schweizer, Tom A. Schweizer, Venkat Bhat, Venkat Bhat, Venkat Bhat, Venkat Bhat   +12 more
doaj   +1 more source

Neural stem cells in Drosophila : molecular genetic mechanisms underlying normal neural proliferation and abnormal brain tumor formation [PDF]

, 2012
Neural stem cells in Drosophila are currently one of the best model systems for understanding stem cell biology during normal development and during abnormal development of stem cell-derived brain tumors.
Heinrich Reichert, Reichert, Heinrich, Saini, Nidhi, Nidhi Saini   +3 more
core   +1 more source

The role of zebrafish (Danio rerio) in dissecting the genetics and neural circuits of executive function [PDF]

, 2013
Zebrafish have great potential to contribute to our understanding of behavioural genetics and thus to contribute to our understanding of the aetiology of psychiatric disease.
Brock, AJ, Walton, Robert T., Walton, RT, Caroline Helen Brennan, Robert T. Walton, Matthew O Parker, Alistair J Brock, Parker, Matthew O., Brennan, Caroline H., Alistair J. Brock, Brennan, CH, Parker, MO, Robert T Walton, Brock, Alistair J., Matthew O. Parker, Caroline H. Brennan   +15 more
core   +1 more source

Chemical Memory in Primitive Organisms: Evolutionary Insights and Mechanistic Perspectives

Exon
Memory, the cornerstone of adaptive behavior, has been extensively studied within the confines of neural systems. A comprehensive literature review was conducted using key academic databases such as PubMed, Web of Science, and Google Scholar.
Saad Ahmed, Haris Ishtiaq Kiani, Muhammad Fahad Shabbir   +2 more
doaj   +1 more source

Parallel Development of Chromatin Patterns, Neuron Morphology, and Connections: Potential for Disruption in Autism

Frontiers in Neuroanatomy, 2018
The phenotype of neurons and their connections depend on complex genetic and epigenetic processes that regulate the expression of genes in the nucleus during development and throughout life.
Miguel Á García-Cabezas, Helen Barbas, Helen Barbas, Basilis Zikopoulos, Basilis Zikopoulos   +4 more
doaj   +1 more source

Mapping the Landscape of Diaschisis in Traumatic Brain Injury: A Scoping Review

Neurotrauma Reports
Diaschisis is a phenomenon in which damage to one brain region leads to dysfunction in remote, yet functionally connected, areas. Although it has been well characterized in stroke, the complex, multifocal nature of traumatic brain injury (TBI) suggests ...
Madison Evans, Cigdem Tosun, Ruchira M. Jha, Prajwal Ciryam, Volodymyr Gerzanich, J. Marc Simard   +5 more
doaj   +1 more source

Regulation of Neural Circuitry under General Anesthesia: New Methods and Findings

Biomolecules, 2022
General anesthesia has been widely utilized since the 1840s, but its underlying neural circuits remain to be completely understood. Since both general anesthesia and sleep are reversible losses of consciousness, studies on the neural-circuit mechanisms ...
Kai Zhang, Jiacheng Pan, Yonghao Yu
doaj   +1 more source