Results 41 to 50 of about 3,455,773 (294)

Interpreting the neural code with formal concept analysis [PDF]

, 2012
This contribution is in volume 1 of 3 for this title.We propose a novel application of Formal Concept Analysis (FCA) to neural decoding: instead of just trying to figure out which stimulus was presented, we demonstrate how to explore the semantic ...
Endres, D, Foldiak, Peter
core   +2 more sources

Mapping the Landscape of Diaschisis in Traumatic Brain Injury: A Scoping Review

Neurotrauma Reports
Diaschisis is a phenomenon in which damage to one brain region leads to dysfunction in remote, yet functionally connected, areas. Although it has been well characterized in stroke, the complex, multifocal nature of traumatic brain injury (TBI) suggests ...
Madison Evans, Cigdem Tosun, Ruchira M. Jha, Prajwal Ciryam, Volodymyr Gerzanich, J. Marc Simard   +5 more
doaj   +1 more source

Leptin signaling and leptin resistance

Medical Review, 2022
With the prevalence of obesity and associated comorbidities, studies aimed at revealing mechanisms that regulate energy homeostasis have gained increasing interest. In 1994, the cloning of leptin was a milestone in metabolic research. As an adipocytokine,
Liu Jiarui, Lai Futing, Hou Yujia, Zheng Ruimao   +3 more
doaj   +1 more source

Parallel Development of Chromatin Patterns, Neuron Morphology, and Connections: Potential for Disruption in Autism

Frontiers in Neuroanatomy, 2018
The phenotype of neurons and their connections depend on complex genetic and epigenetic processes that regulate the expression of genes in the nucleus during development and throughout life.
Miguel Á García-Cabezas, Helen Barbas, Helen Barbas, Basilis Zikopoulos, Basilis Zikopoulos   +4 more
doaj   +1 more source

Neural and hormonal mechanisms of appetite regulation during eating

Frontiers in Nutrition
Numerous animal and clinical studies have demonstrated that the arcuate nucleus of the hypothalamus, a central regulator of appetite, plays a significant role in modulating feeding behavior.
Xurui Sun, Binghan Liu, Yuan Yuan, Ying Rong, Rui Pang, Qiu Li   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Connectomic Analysis of the Human Basal Ganglia Network

Frontiers in Neuroanatomy, 2017
The current model of basal ganglia circuits has been introduced almost two decades ago and has settled the basis for our understanding of basal ganglia physiology and movement disorders.
Alberto Cacciola, Alessandro Calamuneri, Demetrio Milardi, Demetrio Milardi, Enricomaria Mormina, Gaetana Chillemi, Silvia Marino, Antonino Naro, Giuseppina Rizzo, Giuseppe Anastasi, Angelo Quartarone, Angelo Quartarone   +11 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Regulation of Neural Circuitry under General Anesthesia: New Methods and Findings

Biomolecules, 2022
General anesthesia has been widely utilized since the 1840s, but its underlying neural circuits remain to be completely understood. Since both general anesthesia and sleep are reversible losses of consciousness, studies on the neural-circuit mechanisms ...
Kai Zhang, Jiacheng Pan, Yonghao Yu
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source