Results 61 to 70 of about 29,945 (263)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

E-Cadherin regulates neural stem cell self-renewal

, 2009
E-Cadherin, a cell adhesion protein, has been shown to take part in the compartmentalization, proliferation, survival, and differentiation of cells.
DeVeale, B., Willaime-Morawek, S., van der Kooy, D., Balenci, L., Karpowicz, P., Inoue, T.   +5 more
core   +1 more source

Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells [PDF]

, 2006
Embryonic cortical neural stem cells apparently have a transient existence, as they do not persist in the adult cortex. We sought to determine the fate of embryonic cortical stem cells by following Emx1(IREScre); LacZ/EGFP double-transgenic murine cells ...
Seaberg, R.M., Cindi M. Morshead, Morshead, C.M., Kevin R. Jones, Gorski, J.A., Raewyn M. Seaberg, Etienne Labbé, Jessica A. Gorski, Attisano, L., Jones, K.R., Sandrine Willaime-Morawek, Willaime-Morawek, S., Labbé, E., van der Kooy, D., Claudia Batista, Batista, C., Angela Kam, Liliana Attisano, Derek van der Kooy   +18 more
core   +1 more source

Neural Conduction Along Postretinal Visual Pathways in Glaucoma

Frontiers in Aging Neuroscience, 2021
Purpose: This study was conducted in order to evaluate retinal ganglion cell (RCG) function and the neural conduction along the postretinal large and small axons and its correlation with retinal nerve fiber layer thickness (RNFL-T) in open-angle glaucoma
Vincenzo Parisi, Lucia Ziccardi, Lucia Tanga, Gloria Roberti, Lucilla Barbano, Carmela Carnevale, Gianluca Manni, Francesco Oddone   +7 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

FRACTIONAL ANISOTROPY IN DEGENERATIVE CERVICAL STENOSIS SURGERY PROGNOSTIC: A SYSTEMATIC REVIEW [PDF]

Coluna/Columna
Cervical spondylotic myelopathy (CSM) is a common disease with an increased anticipated burden to health systems worldwide. Methods to predict outcomes in these patients are needed so physicians can provide more effective care. Fractional anisotropy (FA)
Leon Cleres Penido Pinheiro, Rodrigo Almeida Cunha, Eloy Rusafa Neto, Roger Schmidt Brock   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Parylene Technology for Neural Probes Applications [PDF]

, 2008
Neural probes are important tools in detecting and studying neuron activities. Although people have been working on neural probe development for a long time, the current neural probes (including metal-wire probes and silicon neural probes) are still far ...
Pang, Changlin
core   +1 more source

Brain-gut-microbiota axis: a review on the bidirectional regulatory mechanisms between gut microbiota and brain and their disease interactions

Frontiers in Microbiology
ObjectiveTo synthesize current evidence on the bidirectional regulatory mechanisms of the Brain-Gut-Microbiota Axis (BGMA), its perturbation by external factors, and its clinical implications for neurodegenerative, psychiatric, metabolic, and ...
Hui Shen, Hui Shen, Hui Shen, Si Yun Wang, Si Yun Wang, Yan Yan Zhao, Yan Yan Zhao, Jia Lin Zhou, Jie Zhao, Wei Kai Zhu   +9 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source