MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System
Cells, 2021 Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries +11 more
doaj +1 more source
Stimulation of neural regeneration in the mouse retina [PDF]
Proceedings of the National Academy of Sciences, 2008 Müller glia can serve as a source of new neurons after retinal damage in both fish and birds. Investigations of regeneration in the mammalian retina in vitro have provided some evidence that Müller glia can proliferate after retinal damage and generate new rods; however, the evidence that this occurs in ...
Michael Karl +5 more
openalex +5 more sources
Biomedicines, 2022 We studied the phenotypes in an oligodendrocyte genesis site at the acute stage of spinal cord injury, when we observed regenerated ascending neurites. Pan-oligodendrocyte marker OLIG2+ cells were more in fibroblast growth factor (FGF)-1-treated rats (F ...
Meng-Jen Lee +9 more
doaj +1 more source
The various routes to functional regeneration in the central nervous system [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Echeverri, K.
Echeverri, Karen
core +1 more source
Advances in Electrospun Nerve Guidance Conduits for Engineering Neural Regeneration
Pharmaceutics, 2022 Injuries to the peripheral nervous system result in devastating consequences with loss of motor and sensory function and lifelong impairments. Current treatments have largely relied on surgical procedures, including nerve autografts to repair damaged ...
S. Behtaj, J. Ekberg, J. S. St John
semanticscholar +1 more source
Recent advances in the application of MXenes for neural tissue engineering and regeneration
Neural Regeneration Research, 2023 Transition metal carbides and nitrides (MXenes) are crystal nanomaterials with a number of surface functional groups such as fluorine, hydroxyl, and oxygen, which can be used as carriers for proteins and drugs.
Menghui Liao +9 more
semanticscholar +1 more source
Machine‐Assisted Discovery of Chondroitinase ABC Complexes toward Sustained Neural Regeneration
Advanced Healthcare Materials, 2022 Among the many molecules that contribute to glial scarring, chondroitin sulfate proteoglycans (CSPGs) are known to be potent inhibitors of neuronal regeneration.
Shashank Kosuri +12 more
semanticscholar +1 more source
Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. [PDF]
, 2020 One million estimated cases of spinal cord injury (SCI) have been reported in the United States and repairing an injury has constituted a difficult clinical challenge.
Anderson, Aileen J +8 more
core +1 more source
Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]
, 2020 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
core +1 more source
Journal of Biomedical Science, 2017 Background Olfactory ensheathing cells (OEC), specialized glia that ensheathe bundles of olfactory nerves, have been reported as a favorable substrate for axonal regeneration.
May-Jywan Tsai +14 more
doaj +1 more source