Results 21 to 30 of about 344,220 (168)

Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule

open access: yesScientific Reports, 2017
Human pluripotent stem cells (hPSCs) play important role in studying the function of human glutamatergic neurons and related disease pathogenesis. However, the current hPSC-derived cortical system produced a significant number of inhibitory GABAergic ...
Shi-Ying Cao   +8 more
doaj   +1 more source

Evolution of abilities to regenerate neurons in central nervous systems [PDF]

open access: yes, 1980
This work was supported by a Kappa Kappa Gamma Graduate Fellowship Award to C. E. H. and NIH grant NS-11861 and RCDA NS-00070 to G. D.
Bittner, George D., Hulsebosch, C.E.
core   +1 more source

Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish

open access: yesMediators of Inflammation, 2019
As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts   +6 more
doaj   +1 more source

The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox

open access: yesCells, 2022
The chronic character of chemogenetics has been put forward as one of the assets of the technique, particularly in comparison to optogenetics. Yet, the vast majority of chemogenetic studies have focused on acute applications, while repeated, long-term ...
Marie Claes, Lies De Groef, Lieve Moons
doaj   +1 more source

The various routes to functional regeneration in the central nervous system [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Echeverri, K.
Echeverri, Karen
core   +1 more source

Defending Against Universal Attacks Through Selective Feature Regeneration [PDF]

open access: yesCVPR 2020, 2019
Deep neural network (DNN) predictions have been shown to be vulnerable to carefully crafted adversarial perturbations. Specifically, image-agnostic (universal adversarial) perturbations added to any image can fool a target network into making erroneous predictions.
arxiv   +1 more source

Interfacing peripheral nerve with macro-sieve electrodes following spinal cord injury [PDF]

open access: yes, 2017
Macro-sieve electrodes were implanted in the sciatic nerve of five adult male Lewis rats following spinal cord injury to assess the ability of the macro-sieve electrode to interface regenerated peripheral nerve fibers post-spinal cord injury. Each spinal
Birenbaum, Nathan K   +2 more
core   +6 more sources

Large-Scale Integration of Single-Cell RNA-Seq Data Reveals Astrocyte Diversity and Transcriptomic Modules across Six Central Nervous System Disorders

open access: yesBiomolecules, 2023
The dysfunction of astrocytes in response to environmental factors contributes to many neurological diseases by impacting neuroinflammation responses, glutamate and ion homeostasis, and cholesterol and sphingolipid metabolism, which calls for ...
Zhenwei Qian   +4 more
doaj   +1 more source

Regenerating Soft Robots through Neural Cellular Automata [PDF]

open access: yesarXiv, 2021
Morphological regeneration is an important feature that highlights the environmental adaptive capacity of biological systems. Lack of this regenerative capacity significantly limits the resilience of machines and the environments they can operate in.
arxiv  

Spinal Progenitor-Laden Bridges Support Earlier Axon Regeneration Following Spinal Cord Injury. [PDF]

open access: yes, 2018
Impact statementSpinal cord injury (SCI) results in loss of tissue innervation below the injury. Spinal progenitors have a greater ability to repair the damage and can be injected into the injury, but their regenerative potential is hampered by their ...
Anderson, Aileen J   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy