Results 21 to 30 of about 93,309 (296)
Cell Reports, 2019 Summary: Under food deprivation conditions, Drosophila larvae exhibit increases in locomotor speed and synaptic bouton numbers at neuromuscular junctions (NMJs).
Keisuke Kamimura +4 more
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Scientific Reports, 2017 Human pluripotent stem cells (hPSCs) play important role in studying the function of human glutamatergic neurons and related disease pathogenesis. However, the current hPSC-derived cortical system produced a significant number of inhibitory GABAergic ...
Shi-Ying Cao +8 more
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Frontiers in Neuroscience, 2021 Background: The carotid body (CB) plays a critical role in oxygen sensing; however, the role of glutamatergic signaling in the CB response to hypoxia remains uncertain.
Chaohong Li +4 more
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Mediators of Inflammation, 2019 As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts +6 more
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Magnetic Composite Biomaterials for Neural Regeneration [PDF]
Frontiers in Bioengineering and Biotechnology, 2019 Nervous system damage caused by physical trauma or degenerative diseases can result in loss of sensory and motor function for patients. Biomaterial interventions have shown promise in animal studies, providing contact guidance for extending neurites or sustained release of various drugs and growth factors; however, these approaches often target only ...
Jessica L Funnell +2 more
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Acta Neuropathologica Communications, 2023 The multifaceted nature of neuroinflammation is highlighted by its ability to both aggravate and promote neuronal health. While in mammals retinal ganglion cells (RGCs) are unable to regenerate following injury, acute inflammation can induce axonal ...
Lien Andries +10 more
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Biotargets in neural regeneration
Biotarget, 2017 The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than the central nervous system (CNS). The main reason is that the neurons in PNS still have certain intrinsic capacity for regeneration and the Schwann cells in PNS provide a suitable regeneration microenvironment.
Songlin Zhou +4 more
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Nanomaterial-Based Approaches for Neural Regeneration [PDF]
Pharmaceutics, 2019 Mechanical, thermal, chemical, or ischemic injury of the central or peripheral nervous system results in neuron loss, neurite damage, and/or neuronal dysfunction, almost always accompanied by sensorimotor impairment which alters the patient’s life quality. The regenerative strategies for the injured nervous system are currently limited and mainly allow
Raluca Ioana Teleanu +5 more
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The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox
Cells, 2022 The chronic character of chemogenetics has been put forward as one of the assets of the technique, particularly in comparison to optogenetics. Yet, the vast majority of chemogenetic studies have focused on acute applications, while repeated, long-term ...
Marie Claes, Lies De Groef, Lieve Moons
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The Application of Brain Organoids in Assessing Neural Toxicity
Frontiers in Molecular Neuroscience, 2022 The human brain is a complicated and precisely organized organ. Exogenous chemicals, such as pollutants, drugs, and industrial chemicals, may affect the biological processes of the brain or its function and eventually lead to neurological diseases ...
Pan Fan +5 more
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