Results 21 to 30 of about 100,520 (190)
Cardiac Neural Crest and Cardiac Regeneration
Cells, 2022 Neural crest cells (NCCs) are a vertebrate-specific, multipotent stem cell population that have the ability to migrate and differentiate into various cell populations throughout the embryo during embryogenesis. The heart is a muscular and complex organ whose primary function is to pump blood and nutrients throughout the body.
Shannon Erhardt, Jun Wang
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hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding. [PDF]
, 2013 This work builds upon our findings that proteins secreted by hESCs exhibit pro-regenerative activity, and determines that hESC-conditioned medium robustly enhances the proliferation of both muscle and neural progenitor cells.
CONBOY, Irina M +7 more
core +2 more sources
Polymer- and Hybrid-Based Biomaterials for Interstitial, Connective, Vascular, Nerve, Visceral and Musculoskeletal Tissue Engineering [PDF]
, 2020 In this review, materials based on polymers and hybrids possessing both organic and inorganic contents for repairing or facilitating cell growth in tissue engineering are discussed.
Abalymov, Anatolii +2 more
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Redirecting regeneration [PDF]
Nature Reviews Neuroscience, 2015 In zebrafish, components of the extracellular matrix help to direct regenerating motor axons to their original targets.
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Neural Regeneration in Caenorhabditis elegans [PDF]
Annual Review of Genetics, 2012 Axon regeneration is a medically relevant process that can repair damaged neurons. This review describes current progress in understanding axon regeneration in the model organism Caenorhabditis elegans. Factors that regulate axon regeneration in C. elegans have broadly similar roles in vertebrate neurons. This means that using C.
Marc Hammarlund, Rachid El Bejjani
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FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source
PTPσ inhibitors promote hematopoietic stem cell regeneration. [PDF]
, 2019 Receptor type protein tyrosine phosphatase-sigma (PTPσ) is primarily expressed by adult neurons and regulates neural regeneration. We recently discovered that PTPσ is also expressed by hematopoietic stem cells (HSCs).
Chute, John P +17 more
core +1 more source
Harnessing migraines for neural regeneration
Neural Regeneration Research, 2018 The success of naturalistic or therapeutic neuroregeneration likely depends on an internal milieu that facilitates the survival, proliferation, migration, and differentiation of stem cells and their assimilation into neural networks. Migraine attacks are an integrated sequence of physiological processes that may protect the brain from oxidative stress ...
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Networking for regeneration [PDF]
Nature Reviews Neuroscience, 2016 A large collaborative study provides a comprehensive analysis of the core molecular networks that are modulated during peripheral axon regrowth after injury.
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source