TTNPB Promotes Human Pluripotent Stem Cell-to-Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S-(5'-adenosyl)-L-homocysteine/Choline Metabolic Network. [PDF]
Du R +17 more
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A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
Molecular Encoding of Ischemic Stroke and its Resolution after Human Neural Stem Cell Therapy by Extracellular Vesicles. [PDF]
Chang C, Wang Y, Liang X, Wang R, Bao X.
europepmc +1 more source
Neural stem cell-delivered oncolytic virus via intracerebroventricular administration enhances glioblastoma therapy and immune modulation. [PDF]
Chai H +13 more
europepmc +1 more source
How neural stem cell therapy promotes brain repair after stroke. [PDF]
Weber RZ, Rust R, Tackenberg C.
europepmc +1 more source
Healthy young human plasma-derived exosomes enhance neural stem cell therapy by suppressing pyroptosis via TXNIP/NLRP3 after intracerebral hemorrhage. [PDF]
Chen J +11 more
europepmc +1 more source
PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation. [PDF]
He L, Wen J, Dai Q.
europepmc +1 more source
Neural stem cell epigenomes and fate bias are temporally coordinated during corticogenesis
Shapira Y +6 more
europepmc +1 more source
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Neural stem/progenitor cell (NPC) cultures are a tool to study the differentiation of neuronal cells and can be used to model disease conditions in studies investigating the pathological mechanisms affecting the development and cellular plasticity of the central nervous system.
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Hormesis and neural stem cells
Free Radical Biology and Medicine, 2022This paper provides a detailed identification and assessment of hormetic dose responses in neural stem cells (NSCs) as identified in a number of animal models and human tissues, with particular emphasis on cell proliferation and differentiation. Hormetic dose responses were commonly observed following administration of a number of agents, including ...
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