Results 31 to 40 of about 441,743 (344)
An efficient platform for astrocyte differentiation from human induced pluripotent stem cells [PDF]
, 2017 Summary: Growing evidence implicates the importance of glia, particularly astrocytes, in neurological and psychiatric diseases. Here, we describe a rapid and robust method for the differentiation of highly pure populations of replicative astrocytes from ...
Abdelaal, Rawan +13 more
core +3 more sources
Hyaluronan, neural stem cells and tissue reconstruction after acute ischemic stroke. [PDF]
, 2013 Focal stroke is a disabling disease with lifelong sensory, motor and cognitive impairments. Given the paucity of effective clinical treatments, basic scientists are developing novel options for protection of the affected brain and regeneration of lost ...
Carmichael, S Thomas, Moshayedi, Pouria
core +1 more source
Stem Cell Reports, 2017 Age-related macular degeneration (AMD) is a common cause of central visual loss in the elderly. Retinal pigment epithelial (RPE) cell loss occurs early in the course of AMD and RPE cell transplantation holds promise to slow disease progression. We report
Richard J. Davis +18 more
doaj +1 more source
Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice
Molecular Brain, 2020 Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network.
Sarivin Vanan +13 more
doaj +1 more source
Proton MR Spectroscopy of Neural Stem Cells: Does the Proton-NMR Peak at 1.28 ppm Function As a Biomarker for Cell Type or State? [PDF]
, 2011 Recently, a peak at 1.28 ppm in proton magnetic resonance spectroscopy (^1H-MRS) of neural stem cells (NSCs) was introduced as a noninterventional biomarker for neurogenesis in vivo. This would be an urgently needed requisite for translational studies in
Brandt, Moritz +9 more
core +1 more source
The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes [PDF]
, 2005 The boundary cap (BC) is a transient neural crest-derived group of cells located at the dorsal root entry zone (DREZ) that have been shown to differentiate into sensory neurons and glia in vivo.
Cederberg, A +6 more
core +2 more sources
Introduction to Neural Stem Cells [PDF]
Stroke, 2007 Neural stem cells self-renew and give rise to neurons, astrocytes and oligodendrocytes. These cells hold great promise for neural repair after injury or disease. However, a great deal of information needs to be gathered before optimally using neural stem cells for neural repair.
openaire +2 more sources
Stem Cell Reports, 2014 Transplantation of the retinal pigment epithelium (RPE) is being developed as a cell-replacement therapy for age-related macular degeneration. Human embryonic stem cell (hESC) and induced pluripotent stem cell (iPSC)-derived RPE are currently translating
Boris V. Stanzel +10 more
doaj +1 more source
Stem Cell Research & Therapy, 2020 Background Significant developments in stem cell therapy for Parkinson’s disease (PD) have already been achieved; however, methods for reliable assessment of dopamine neuron maturation in vivo are lacking.
Julian L. Goggi +23 more
doaj +1 more source
Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]
, 2017 The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E +4 more
core +1 more source