The stem cells of the neural crest [PDF]
Cell Cycle, 2008 In the vertebrate embryo, the neurectodermal neural crest cells (NCC) have remarkably broad potencies, giving rise, after a migratory phase, to neurons and glial cells in the peripheral nervous system, and to skin melanocytes, being all designated here as "neural" derivatives.
Nicole M. Le Douarin +2 more
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Stem Cell Reports, 2017 Age-related macular degeneration (AMD) is a common cause of central visual loss in the elderly. Retinal pigment epithelial (RPE) cell loss occurs early in the course of AMD and RPE cell transplantation holds promise to slow disease progression. We report
Richard J. Davis +18 more
doaj +1 more source
Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice
Molecular Brain, 2020 Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network.
Sarivin Vanan +13 more
doaj +1 more source
Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]
, 2017 The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E +4 more
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Physiological Plasticity of Neural-Crest-Derived Stem Cells in the Adult Mammalian Carotid Body [PDF]
, 2017 Adult stem cell plasticity, or the ability of somatic stem cells to cross boundaries and differentiate into unrelated cell types, has been amatter of debate in the last decade.
Annese, Valentina +3 more
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Proton MR Spectroscopy of Neural Stem Cells: Does the Proton-NMR Peak at 1.28 ppm Function As a Biomarker for Cell Type or State? [PDF]
, 2011 Recently, a peak at 1.28 ppm in proton magnetic resonance spectroscopy (^1H-MRS) of neural stem cells (NSCs) was introduced as a noninterventional biomarker for neurogenesis in vivo. This would be an urgently needed requisite for translational studies in
Brandt, Moritz +9 more
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Hyaluronan, neural stem cells and tissue reconstruction after acute ischemic stroke. [PDF]
, 2013 Focal stroke is a disabling disease with lifelong sensory, motor and cognitive impairments. Given the paucity of effective clinical treatments, basic scientists are developing novel options for protection of the affected brain and regeneration of lost ...
Carmichael, S Thomas, Moshayedi, Pouria
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Neural stemness contributes to cell tumorigenicity [PDF]
Cell & Bioscience, 2020 Abstract Background Previous studies demonstrated the dependence of cancer on nerve. Recently, a growing number of studies reveal that cancer cells share the property and regulatory network with neural stem/progenitor cells. However, relationship between the property of neural stemness and cell tumorigenicity is unknown.
Liyang Xu +7 more
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Stem Cell Reports, 2014 Transplantation of the retinal pigment epithelium (RPE) is being developed as a cell-replacement therapy for age-related macular degeneration. Human embryonic stem cell (hESC) and induced pluripotent stem cell (iPSC)-derived RPE are currently translating
Boris V. Stanzel +10 more
doaj +1 more source
The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes [PDF]
, 2005 The boundary cap (BC) is a transient neural crest-derived group of cells located at the dorsal root entry zone (DREZ) that have been shown to differentiate into sensory neurons and glia in vivo.
Cederberg, A +6 more
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