Results 51 to 60 of about 1,438,323 (398)

Human RPE Stem Cells Grown into Polarized RPE Monolayers on a Polyester Matrix Are Maintained after Grafting into Rabbit Subretinal Space

Stem Cell Reports, 2014
Transplantation of the retinal pigment epithelium (RPE) is being developed as a cell-replacement therapy for age-related macular degeneration. Human embryonic stem cell (hESC) and induced pluripotent stem cell (iPSC)-derived RPE are currently translating
Boris V. Stanzel, Zengping Liu, Sudawadee Somboonthanakij, Warapat Wongsawad, Ralf Brinken, Nicole Eter, Barbara Corneo, Frank G. Holz, Sally Temple, Jeffrey H. Stern, Timothy A. Blenkinsop   +10 more
doaj   +1 more source

A Computational Model Incorporating Neural Stem Cell Dynamics Reproduces Glioma Incidence across the Lifespan in the Human Population [PDF]

Bauer, Roman, Marcus Kaiser, and Elizabeth Stoll. "A Computational Model Incorporating Neural Stem Cell Dynamics Reproduces Glioma Incidence across the Lifespan in the Human Population." PloS one 9.11 (2014): e111219, 2015
Glioma is the most common form of primary brain tumor. Demographically, the risk of occurrence increases until old age. Here we present a novel computational model to reproduce the probability of glioma incidence across the lifespan. Previous mathematical models explaining glioma incidence are framed in a rather abstract way, and do not directly relate
arxiv   +1 more source

Evaluation of Dynamic Cell Processes and Behavior Using Video Bioinformatics Tools [PDF]

, 2015
Just as body language can reveal a person’s state of well-being, dynamic changes in cell behavior and morphology can be used to monitor processes in cultured cells.
A Valavanidis, BE Lehnert, C Ballestrem, C Carlson, C Gieseke, CC Wong, DA Drechsel, DR Albrecht, E Hinchcliffe, F Li, G DiCarlantonio, G Schatten, GG Martin, K Riveles, K Riveles, K Riveles, K Riveles, KL Tsai, M Knoll, M Knoll, M Williams, P Talbot, P Talbot, P Talbot, RZ Behar, RZ Behar, S Inoué, S Lin, S Lin, S Lin, T Haraguchi, T Ichikawa, V Adler, V Bahl, VJ Thannickal, Y Wang   +35 more
core   +1 more source

Human neural stem cells

Cell Proliferation, 2023
Abstract‘Human neural stem cells’ jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human neural stem cells (hNSCs) in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packaging requirements ...
Yu‐Kai Wang, Juan Yu, Ting‐Ting Zhang, Ai‐Jin Ma, Jie Hao, Yue‐Jun Chen, Chang‐Mei Liu, Yan Liu, Chang‐Lin Wang, Pei‐Jun Zhai, Andy Peng Xiang, Tian‐Qing Li, Tie‐Shan Tang, Hong Chen, Xin‐Jie Bao, Yan‐Lin Wang, Wen‐Yan He, Jing Fan, Zhao‐Qian Teng, Liu Wang, Jia‐Xi Zhou, Bo‐Qiang Fu, Yu Vincent Fu, Lin Feng, Jia‐Ni Cao, Ling‐Min Liang, Lei Wang, Qi Zhou, Yu Zhang, Bao‐Yang Hu, Tong‐Biao Zhao   +30 more
openaire   +2 more sources

Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in the Murine Thromboembolic Stroke Model

Translational Stroke Research, 2017
Over 700 drugs have failed in stroke clinical trials, an unprecedented rate thought to be attributed in part to limited and isolated testing often solely in “young” rodent models and focusing on a single secondary injury mechanism.
Robin L. Webb, Erin E Kaiser, S. Scoville, Tyler A. Thompson, Sumbul Fatima, C. Pandya, Karishma Sriram, R. Swetenburg, K. Vaibhav, A. Arbab, B. Baban, K. Dhandapani, D. Hess, M. Hoda, S. Stice   +14 more
semanticscholar   +1 more source

First steps to define murine amniotic fluid stem cell microenvironment [PDF]

, 2016
Stem cell niche refers to the microenvironment where stem cells reside in living organisms. Several elements define the niche and regulate stem cell characteristics, such as stromal support cells, gap junctions, soluble factors, extracellular matrix ...
Bertin, Enrica, Bonaldo, Paolo, Braghetta, Paola, DE COPPI, Paolo, Dedja, Arben, Dona', Silvia, Franzin, Chiara, Piccoli, Martina, Pozzobon, Michela, Schiavi, Francesca, Spiro, Giovanna, Taschin, E.   +11 more
core   +2 more sources

Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program

Nature Neuroscience, 2018
Ectopic expression of defined transcription factors can force direct cell-fate conversion from one lineage to another in the absence of cell division. Several transcription factor cocktails have enabled successful reprogramming of various somatic cell ...
Marisa Karow, Marisa Karow, J. G. Camp, S. Falk, Tobias Gerber, Abhijeet Pataskar, Malgorzata Gac-Santel, J. Kageyama, Agnieska Brazovskaja, A. Garding, Wenqiang Fan, T. Riedemann, Antonella Casamassa, Antonella Casamassa, Andrej Smiyakin, C. Schichor, M. Götz, V. Tiwari, Barbara Treutlein, Barbara Treutlein, B. Berninger   +20 more
semanticscholar   +1 more source

Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease

Stem Cell Research & Therapy, 2020
Background Significant developments in stem cell therapy for Parkinson’s disease (PD) have already been achieved; however, methods for reliable assessment of dopamine neuron maturation in vivo are lacking.
Julian L. Goggi, Lifeng Qiu, Mei Chih Liao, Shivashankar Khanapur, Lingfan Jiang, Ramasamy Boominathan, Siddesh V. Hartimath, Peter Cheng, Fui Fong Yong, Vanessa Soh, Xiaozhou Deng, Youshan Melissa Lin, Anna Haslop, Peng Wen Tan, Xiaoxia Zeng, Jolene W. L. Lee, Zhiwei Zhang, Pragalath Sadasivam, Eng King Tan, Sajinder K. Luthra, William D. Shingleton, Steve K. W. Oh, Li Zeng, Edward G. Robins   +23 more
doaj   +1 more source

Neural stemness contributes to cell tumorigenicity [PDF]

Cell & Bioscience, 2020
Abstract Background Previous studies demonstrated the dependence of cancer on nerve. Recently, a growing number of studies reveal that cancer cells share the property and regulatory network with neural stem/progenitor cells. However, relationship between the property of neural stemness and cell tumorigenicity is unknown.
Liyang Xu, Min Zhang, Lihua Shi, Xiaoli Yang, Lu Chen, Ning Cao, Anhua Lei, Ying Cao   +7 more
openaire   +4 more sources

Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division

Frontiers in Neuroscience, 2020
A population of neural stem cells (NSCs) dwelling in the dentate gyrus (DG) is able to generate neurons throughout adult life in the hippocampus of most mammals. These NSCs generate also astrocytes naturally and are capable of generating oligodendrocytes
Roberto Valcárcel-Martín, Roberto Valcárcel-Martín, Soraya Martín-Suárez, Teresa Muro-García, Teresa Muro-García, Oier Pastor-Alonso, Oier Pastor-Alonso, Fernando Rodríguez de Fonseca, Guillermo Estivil-Torrús, Juan Manuel Encinas, Juan Manuel Encinas, Juan Manuel Encinas   +11 more
doaj   +1 more source