Results 61 to 70 of about 1,045,843 (356)
Introduction to Neural Stem Cells [PDF]
Stroke, 2007 Neural stem cells self-renew and give rise to neurons, astrocytes and oligodendrocytes. These cells hold great promise for neural repair after injury or disease. However, a great deal of information needs to be gathered before optimally using neural stem cells for neural repair.
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Nature Communications, 2023 The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and neural crest-derived craniofacial structures are unclear.
Anthony J. Asmar +13 more
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Molecular Biomarkers for Embryonic and Adult Neural Stem Cell and Neurogenesis
BioMed Research International, 2015 The procedure of neurogenesis has made numerous achievements in the past decades, during which various molecular biomarkers have been emerging and have been broadly utilized for the investigation of embryonic and adult neural stem cell (NSC ...
Juan Zhang, Jianwei Jiao
semanticscholar +1 more source
Neural Stem Cells and Neurogenesis in the Adult [PDF]
Cell Stem Cell, 2012 Research in the field of adult neurogenesis has seen substantial progress over recent years. Here we discuss some of the major focus areas for future investigation: neural stem cell heterogeneity, the role of latent stem cells, and the extent of neurogenesis in the adult human brain.
Göritz C, Frisén J.
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
Nature Communications, 2019 The hepatopancreatic ductal (HPD) system connects both liver and pancreas to the intestine but the molecular details of HPD development are unclear. Here, the authors describe how regionalised Eph/Ephrin signaling regulates HPD morphogenesis by promoting
M. Ilcim Thestrup +9 more
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Emerging understanding of apoptosis in mediating mesenchymal stem cell therapy
Cell Death and Disease, 2021 Mesenchymal stem cell transplantation (MSCT) has been recognized as a potent and promising approach to achieve immunomodulation and tissue regeneration, but the mechanisms of how MSCs exert therapeutic effects remain to be elucidated. Increasing evidence
Yu Fu +6 more
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Stem Cell Therapy for Spinal Cord Injury
Cell Transplantation, 2021 Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues, which results in motor and sensory dysfunction, dystonia, and pathological reflex that ultimately lead to paraplegia or tetraplegia.
Liyi Huang +4 more
semanticscholar +1 more source
MicroRNAs in Neural Stem Cells and Neurogenesis [PDF]
Frontiers in Neuroscience, 2012 MicroRNA (miRNA) is a type of short-length (~22 nt) non-coding RNA. Most miRNAs are transcribed by RNA polymerase II and processed by Drosha-DGCR8 and Dicer complexes in the cropping and dicing steps, respectively. miRNAs are exported by exportin-5 from the nucleus to the cytoplasm after cropping.
Hironori Kawahara +3 more
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