Results 31 to 40 of about 1,237,621 (358)

Neural stem cell secretome and its role in the treatment of neurodegenerative disorders [PDF]

open access: yesJournal of Integrative Neuroscience, 2020
Neurological diseases in the central nervous system are mostly characterized by the failure of endogenous repair to restore tissue damage and salvage lost function.
Qian Zhang, Jia Li , Wenqiang An, Yiou Fan, Qilong Cao
doaj   +1 more source

Using Deep Learning to Predict Neural Stem Cell Differentiation in Regenerative Medicine [PDF]

open access: yesarXiv, 2023
Over one in three people are affected by neurodegenerative disorders. Neural stem cells, which are multipotent regenerative cells with the potential to differentiate into any of the neural cell types, have immense therapeutic potential for treating neurological disorders.
arxiv  

Perspective: Of Mice and Men – How Widespread Is Adult Neurogenesis?

open access: yesFrontiers in Neuroscience, 2019
These are exciting times for research on adult hippocampal neurogenesis (AHN). Debate and controversy regarding the existence of generation of new neurons in the adult, and even diseased human brain flourishes as articles against and in favor accumulate.
David Petrik   +5 more
doaj   +1 more source

A Computational Model Incorporating Neural Stem Cell Dynamics Reproduces Glioma Incidence across the Lifespan in the Human Population [PDF]

open access: yesBauer, Roman, Marcus Kaiser, and Elizabeth Stoll. "A Computational Model Incorporating Neural Stem Cell Dynamics Reproduces Glioma Incidence across the Lifespan in the Human Population." PloS one 9.11 (2014): e111219, 2015
Glioma is the most common form of primary brain tumor. Demographically, the risk of occurrence increases until old age. Here we present a novel computational model to reproduce the probability of glioma incidence across the lifespan. Previous mathematical models explaining glioma incidence are framed in a rather abstract way, and do not directly relate
arxiv   +1 more source

Human neural stem cells

open access: yesCell Proliferation, 2023
Abstract‘Human neural stem cells’ jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human neural stem cells (hNSCs) in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packaging requirements ...
Yu‐Kai Wang   +30 more
openaire   +2 more sources

New insights into the biological roles of immune cells in neural stem cells in post-traumatic injury of the central nervous system

open access: yesNeural Regeneration Research, 2023
Traumatic injuries in the central nervous system, such as traumatic brain injury and spinal cord injury, are associated with tissue inflammation and the infiltration of immune cells, which simultaneously affect the self-renewal and differentiation of ...
Ning He   +5 more
doaj   +1 more source

Current progress in the derivation and therapeutic application of neural stem cells

open access: yesCell Death and Disease, 2017
Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on NSC transplantation is a promising tool for the treatment of nervous system diseases.
Yuewen Tang, Pei Yu, Lin Cheng
semanticscholar   +1 more source

Neural stemness contributes to cell tumorigenicity [PDF]

open access: yesCell & Bioscience, 2020
Abstract Background Previous studies demonstrated the dependence of cancer on nerve. Recently, a growing number of studies reveal that cancer cells share the property and regulatory network with neural stem/progenitor cells. However, relationship between the property of neural stemness and cell tumorigenicity is unknown.
Liyang Xu   +7 more
openaire   +4 more sources

Oscillating field stimulation promotes neurogenesis of neural stem cells through miR-124/Tal1 axis to repair spinal cord injury in rats

open access: yesNeural Regeneration Research, 2023
Spinal cord injury often leads to severe motor and sensory deficits, and prognosis using the currently available therapies remains poor. Therefore, we aimed to explore a novel therapeutic approach for improving the prognosis of spinal cord injury.
Chao Fang   +3 more
doaj   +1 more source

Transplantation of erythropoietin gene-modified neural stem cells improves the repair of injured spinal cord

open access: yesNeural Regeneration Research, 2015
The protective effects of erythropoietin on spinal cord injury have not been well described. Here, the eukaryotic expression plasmid pcDNA3.1 human erythropoietin was transfected into rat neural stem cells cultured in vitro.
Min-fei Wu   +5 more
doaj   +1 more source

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