The silent tragic reality of Hidden Hunger, anaemia, and neural-tube defects (NTDs) in India. [PDF]
Hidden Hunger arising from nutritional iron-, folate-, and vitamin-B12-deficiencies is exceedingly common in India and has profound negative impacts on anaemia, on pregnancy, and on embryonic-foetal neurodevelopment in utero, which predisposes to NTDs and psychological-psychiatric manifestations in childhood. Whereas younger-to-middle-aged Indians fail
Antony AC, Vora RM, Karmarkar SJ.
europepmc +4 more sources
The recurrence risk of neural tube defects (NTDs) in a population with high prevalence of NTDs in northern China. [PDF]
Although a number of studies have reported the recurrence risk of NTDs in developed countries, there is little data on the rate of recurrence of NTDs in northern China, a region of high prevalence of NTDs.Based on the population-based birth defects surveillance system of five counties, we identified women who had an NTD affected pregnancy from 2004 ...
Liu J, Li Z, Greene NDE, Li H, Ren A.
europepmc +4 more sources
Evaluation of Neural Tube Defects (NTDs) After Exposure to Raltegravir During Pregnancy. [PDF]
Objective: To evaluate the risk of neural tube defects (NTDs) after exposure to raltegravir during pregnancy. Methods: Exposures to raltegravir during pregnancy reported cumulatively through May 31, 2018, to the company safety database were reviewed to identify cases of NTDs.
Shamsuddin H +8 more
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Morphological Variants and Factors Associated With Neural Tube Defects at a Regional Referral Hospital. [PDF]
ABSTRACT Background Neural Tube Defects (NTDs) remain a significant public health concern, especially in low‐resource settings. This study investigated the morphological variants of NTDs and identified factors associated with their development among neonates at Mbarara Regional Referral Hospital (MRRH).
Owere B +3 more
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Background: The most common congenital malformations are Neural tubedefects (NTDs) occurring in 0.6 per 1,000 live births in the United States, and almost 4000pregnancies are recorded of babies with neural tube defects, among them anencephalyand Spina bifida are the most common and their annual incidence is 2,500 to 3,000 births inthe United States ...
Nadeem Shahzad +3 more
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Prenatal exome sequencing of fetuses with central nervous system anomalies based on prenatal ultrasound and magnetic resonance imaging diagnosis: A retrospective cohort study with a systematic review and meta-analysis. [PDF]
Prenatal exome sequencing significantly improves diagnostic yield over chromosomal microarray analysis for fetal CNS abnormalities, with a diagnostic yield of 16% in our cohort and 27% in the meta‐analysis. Diagnostic yields vary across different phenotypes. Abstract Introduction Fetal central nervous system (CNS) abnormalities have diverse etiologies,
Yao J +5 more
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Folic Acid and the Prevention of Neural Tube Defects (NTDs) [PDF]
To outline specific challenges facing public health in Canada that need to be addressed to ensure that all women of childbearing years can attain optimal folate status for prevention of NTDs.The new Dietary Reference Intake (DRI) for folate was examined in terms of the literature on the effective form of the vitamin, the level of folic acid provided by
Heidi S, Reisch, Mary A T, Flynn
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TOENAIL ZINC (Zn) IN MOTHERS OF PROGENY WITH NEURAL TUBE DEFECTS (NTDS) [PDF]
Diet-induced Zn deficiency in pregnant rats is known to cause cong. malfs. in 90-100% of their progeny, some 3% having spina bifida(SB).Mothers of children with SB have been reported to have high concentrations of hair Zn. Recent UK claims suggest vitamin A/folic acid periconceptional supplementation dramatically reduces the rate of recurrence of NTDs ...
Aubrey Milunsky +2 more
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NEURAL TUBE DEFECTS (NTD): FAMILY STUDIES [PDF]
A population of 360 families, with at least one child with anencephaly and/or myelomeningocele or encephalomeningocele was ascertained by multiple selection in the Southern Poland where the birth prevalence of NTD is 0.89/1000. The probability of ascertairment π equalled 0:64; The population birth prevalence of NTD and the prevalence of NTD among the ...
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THE CONTRIBUTION OF COBALAMINE METABOLISM TO GENETIC LIABILITY OF NEURAL TUBE DEFECTS (NTD) [PDF]
To check the hypothesis that alteration of cobalamine metabolism may contribute to the etiology of NTD, serum and amniotic fluid levels of total transcobalamlnes (STTC, FTTC) and transcobalamine II (STCII, FTCII) were studied in the pregnancies of high and low risk for NTD development.
Jacek J Pietrzyk +3 more
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